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Shampa Chatterjee, Ph.D.
Research Assistant Professor of Physiology
Department: Physiology
Contact information
Institute for Environmental Medicine,
1 John Morgan
Philadelphia, PA 19104
1 John Morgan
Philadelphia, PA 19104
Office: 215 898 9101 (Off)
Fax: 215 898 0868
Fax: 215 898 0868
Email:
shampac@mail.med.upenn.edu
shampac@mail.med.upenn.edu
Education:
PhD (Biochemistry)
Indian Institute of Technology, Bombay, India, 1997.
PhD (Biochemistry)
Indian Institute of Technology, Bombay, India, 1997.
Post-Graduate Training
Postdoctoral Fellow, Institute for Environmental Medicine, University of Pennsylvania School of Medicine, 1999-2002.
Research Associate, Institute for Environmental Medicine, University of Pennsylvania School of Medicine, 2002-2006.
Permanent linkPostdoctoral Fellow, Institute for Environmental Medicine, University of Pennsylvania School of Medicine, 1999-2002.
Research Associate, Institute for Environmental Medicine, University of Pennsylvania School of Medicine, 2002-2006.
Description of Research Expertise
endothelium, oxidative stress, lung biology, mechanotransduction, angiogenesisSelected Publications
Chatterjee S, Feinstein SI, Dodia C, Sorokina E, Lien YC, Nguyen S, Debolt K, Speicher D, Fisher AB. : Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages. J Biol Chem. 2011 Am Society for Biochemistry and Molecular Biology, 286: 11696-706, 2011.Chatterjee, S, Browning, E.A., Hong, N., DeBolt, K., Sorokina, E., Liu, W. and Aron B. Fisher: Membrane depolarization is the trigger for PI3Kinase/Akt activation and leads to the generation of reactive oxygen species. American Journal of Physiology: Heart and Circ Physiology IN PRESS 2011 Notes: in press.
Mangalmurti, N.S., Chatterjee, S., Chen, G., Anderson, E., Mohammed, A., Siegel, D.L., Schmidt, A.M., Albelda, S.M. and Lee, J.S., : Advanced Glycation Endproducts on Stored Erythrocytes increase Endothelial Reactive Oxygen Species Generation through Interaction with RAGE. Transfusion Paul N, Ness (eds.). Wiley-Blackwell, 50: 2353-61, November 2010.
Lee, J.C. Kinniry, P.A., Arguiri, E. Serota, M. Kanterakis, S., Chatterjee, S. Solomides, S.C, Prashanthi, J., Koumenis, C., Cengel, K.A., and Christofidou-Solomidou, M. : Dietary curcumin increases Antioxidant Defenses in Lung, ameliorates radiation induced pulmonary fibrosis and improves survival in mice. Radiation Research 2010 May;173(5):590-601. Sara Rockwell (eds.). Allen Press, Inc 173(5): 590-601, May 2010.
Milovanova, Tatyana. Chatterjee, Shampa. Hawkins, Brian J. Hong, Nankang. Sorokina, Elena M. Debolt, Kris. Moore, Jonni S. Madesh, Muniswamy. Fisher, Aron B.: Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress. Biochimica et Biophysica Acta 1783(10): 1866-75, Oct 2008.
Zhang, Qunwei. Chatterjee, Shampa. Wei, Zhihua. Liu, Wei Dong. Fisher, Aron B.: Rac and PI3 kinase mediate endothelial cell-reactive oxygen species generation during normoxic lung ischemia. Antioxidants & Redox Signaling 10(4): 679-89, Apr 2008.
Lee, J.C., Bhora, F., Sun,G., Cheng,G., Solomides,C., Arguiri,E., Chatterjee, S., Christofidou-Solomidou, M., : Dietary Flaxseed ameliorates lung ischemia/reperfusion injury via ROS detoxification and decreased ROS production. American Journal of Physiology, Lung Cellular Molecular Physiology 294(L255-65), Feb 2008.
Chatterjee, S. Levitan, I. Wei, Z. Fisher, A B.: KATP channels are an important component of the shear-sensing mechanism in the pulmonary microvasculature. Microcirculation 13(8): 633-44, Dec 2006.
Milovanova, Tatyana. Chatterjee, Shampa. Manevich, Yefim. Kotelnikova, Irina. Debolt, Kris. Madesh, Muniswamy. Moore, Jonni S. Fisher, Aron B.: Lung endothelial cell proliferation with decreased shear stress is mediated by reactive oxygen species. American Journal of Physiology - Cell Physiology 290(1): C66-76, Jan 2006.
Zhang, Qunwei. Matsuzaki, Ikuo. Chatterjee, Shampa. Fisher, Aron B.: Activation of endothelial NADPH oxidase during normoxic lung ischemia is KATP channel dependent. American Journal of Physiology - Lung Cellular & Molecular Physiology 289(6): L954-61, Dec 2005.
