Department of Anesthesiology and Critical Care

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Renyu Liu, M.D., M.S., Ph.D.

Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania
Attending Anesthesiologist, Hospital of the University of Pennsylvania, Philadelphia, PA
Co-Director of Penn-China Anesthesia Partnership Program, University of Pennsylvania School of Medicine
Director of Preoperative Medicine, Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine
Department: Anesthesiology and Critical Care

Contact information
Department of Anesthesiology and Critical Care
336 John Morgan Building
3620 Hamilton Walk
Philadelphia, PA 19104
Office: 2156623750
Fax: 2153495078
Education:
M.D. (Medicine)
Xuzhou Medical College, China, 1990.
MS
Jiaotong University School of Medicine, China, 1993.
Ph.D.
Tottori University School of Medicine, Japan, 2000.
Post-Graduate Training
Resident in Anesthesiology, Renji Hospital, Shanghai Second Medical University, Shanghai, China, 1993-1995.
Postdoctoral Research Fellow, University of Pennsylvania, Philadelphia, PA, 2001-2004.
Intern in Medicine, Mercy Fitzgerald Hospital/Mercy Hospital of Philadelphia, PA, 2004-2005.
Resident in Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, PA, 2005-2008.
Certifications
American Board of Anesthesiology Certified, 2009.
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Description of Research Expertise

My major research interests are as follows:
1) To investigate the molecular recognition mechanism of opioids and their receptors using biophysical, biochemical, thermodynamic, protein engineering, and high-resolution structural approaches.
2) Pharmacological effects of opioid receptor agonists.
3) Anesthetic interaction with proteins
4) Preoperative evaluation and outcome

Description of Clinical Expertise

Anesthesia for general surgery patients
Perioperative Medicine
outside OR anesthesia services
optimal opioid usage in perioperative period

Description of Other Expertise

Partnership with Chinese anesthesiolgists

Selected Publications

Wang Z, Hong T, Liu R: Central nervous system complication after anesthesia. Current Anesthesiology. Hang Y (eds.). Shanghai Publishing House of Science and Technology, Page: in press, 2012.

Liu R, Perez-Aguilar JM, Liang D, Saven JG: Binding site and affinity prediction of general anesthetics to protein targets using docking. Anesthesia & Analgesia in press 2012.

Su D, Riley J, Kiessling WJ, Armstead WM, Liu R: Salvinorin A pretreatment preserves cerebrovascular autoregulation after brain hypoxic/ischemic injury via ERK/MAPK in piglets. Anesthesia & Analgesia Nov 10 [Epub ahead of print] 2011.

Pryzbylkowski P, Dunkman WJ, Liu R, Chen L: Anti-NMDA receptor encephalitis and its anesthetic implications. Anesthesia & Analgesia 113(5): 1188-91, Nov 2011.

Zhou R, Perez-Aguilar JM, Meng Q, Saven JG, Liu R: Opioid binding sites in human serum albumin. Anesthesia & Analgesia 114(1): 122-8, Oct 24 [Epub ahead of print] 2011.

Liu R: Chinese society of anesthesiology entering the world stage. Anesthesiology Page 2 Oct 2011 Notes: http://page2anesthesiology.org/2011/chinese-society-of-anesthesiology-entering-the-world-stage/

Su D, Riley J, Kiessling WJ, Armstead WM, Liu R : Salvinorin A produces cerebrovasodilation through activation of nitric oxide synthase, κ receptor, and adenosine triphosphate-sensitive potassium channel. Anesthesiology 114(2): 374-9, Feb 2011.

Chuy K, Yan Z, Smith DS, Fleisher LA, Liu R: Newly designed preoperative evaluation form for ICU patients to help reduce missing preoperative information. Anesthesiology Page: A1197, 2011.

Resnick KS, Speck RM, Keogh JH, Liu R, Fleisher LA: Effect of a pre-operative phone call on patient satisfaction with anesthesia. Association of University of Anesthesiologists Page: C4, 2011.

Liu R, Su D, Riley J, Armstead WM: Salvinorin A pretreatment preserves pial artery autoregulation via ERK after hypoxia/ischemia in the newborn piglet. Association of University of Anesthesiologists Page: NB6, 2011.

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Last updated: 02/09/2012
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