Department of Anesthesiology and Critical Care

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Alexis A. Topjian, MD

Assistant Professor of Anesthesiology and Critical Care at the Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care

Contact information
The Children's Hospital of Philadelphia
Department of Anesthesia and Critical Care Medicine
34th Street and Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-3915
Fax: 215-590-4327
B.A. (Biology)
Harvard College, 1996.
M.D. (Medicine)
Columbia College of Physicians & Surgeons, 2001.
M.S.C.E. (Masters in Clinical Epidemiology and Biostatistics)
University of Pennsylvania School of Medicine, 2011.
Post-Graduate Training
Resident in Pediatrics, The Children's Hospital of Philadelphia, 2001-2004.
Fellowship in Critical Care Medicine, The Children's Hospital of Philadelphia, 2004-2007.
Pediatric Advanced Life Support - Instructor, 2007.
Advanced Cardiac Life Support, 2015.
American Board of Pediatrics, 2015.
Pediatric Advanced Life Support, 2015.
Sub-Board of Pediatric Critical Care, 2015.
Advanced Trauma Life Support, 2016.
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Selected Publications

Wagenman KL, Blake TP, Sanchez SM, Schultheis MT, Radcliffe J, Berg RA, Dlugos DJ, Topjian AA, Abend NS: Electrographic status epilepticus and long-term outcome in critically ill children. Neurology 82(5): 396-404, February 2014.

Perman S, Goyal M, Neumar R, Topjian AA, Gaieski D: Clinical applications of targeted temperature management. Chest 145(2): 386-393, February 2014.

Wolfe HA, Zebuhr C, Topjian AA, Nishisaki A, Niles DE, Meaney PA, Boyle L, Giordano RT, Davis DH, Priestley MA, Apkon M, Berg RA, Nadkarni VM, Sutton RM: Interdisciplinary intensive care unit cardiac arrest debriefing improves survival outcomes. Critical Care Medicine In Press 2014.

Topjian AA, French B, Sutton RM, Conlon TW, Nadkarni VM, Moler FW, Dean JM, Berg RA: Early post-resuscitation hypotension is associated with increased mortality following pediatric cardiac arrest. Critical Care Medicine In Press 2014.

Topjian AA, Stuart A, Pabalan AA, Clair A, Kilbaugh TJ, Abend NS, Berg RA, Heuer GG, Storm PB, Huh JW, Friess SH: Risk factors associated with infections and need for permanent cerebrospinal fluid diversion in pediatric intensive care patients with externalized ventricular drains. Neurocritical Care In Press 2014.

Nitta M, Kitamura T, Iwami T, Nadkarni VM, Berg RA, Topjian AA, Okamoto Y, Nishiyama C, Nishiuchi T, Hayashi Y, Nishimoto Y, Takasu A: Out-of-hospital cardiac arrest due to drowning among children and adults from the Utstein Osaka Project. Resuscitation 84(11): 1568-1573, November 2013.

Topjian AA, Clark AE, Casper TC, Berger JT, Schleien CL, Dean JM, Moler FW for the Pediatric Emergency Care Applied Research Network: Early lactate elevations following resuscitation from pediatric cardiac arrest are associated with increased mortality. Pediatric Critical Care Medicine 14(8): e380-e387, October 2013.

Hasbani DM, Topjian AA, Friess SH, Kilbaugh TJ, Berg RA, Christian CW, Dlugos DJ, Huh JW, Abend NS: Non-convulsive electrographic seizures are common in children with abusive head trauma. Pediatric Critical Care Medicine 14(7): 709-715, September 2013.

Pensirkul A, Beslow LA, Kessler SK, Sanchez SM, Topjian AA, Dlugos DJ, Abend NS: Density spectral array for seizure identification in critically ill children. Journal of Clinical Neurophysiology 30(4): 371-5, August 2013.

Yehya N, Topjian AA, Lin RJ, Berg RA, Thomas NJ, Friess SH: High frequency oscillation and airway pressure release ventilation in pediatric respiratory failure. Pediatric Pulmonology July 2013.

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Last updated: 03/11/2014
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