Department of Anesthesiology and Critical Care

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Jonas S. Johansson

Associate Professor of Anesthesiology and Critical Care
Department: Anesthesiology and Critical Care

Contact information
HUP- 801 DULLES
3400 Spruce Street
4283
Philadelphia, PA 19104
Office: 2156623715
Education:
BS
University of Miami, 1984.
Ph.D. (Pharmacology)
University of Miami, 1990.
M.D.
University of Miami, 1990.
Post-Graduate Training
Medicine Intern, Jackson Memorial Hospital, Miami, FL, 1990-1991.
Anesthesiology Resident, Hospital of the University of Pennsylvania, Philadelphia, PA, 1991-1994.
Anesthesiology Fellow, Johnson Research Foundation, Mentor: PL Dutton, FRS, University of Pennsylvania, Philadelphia, PA, 1994-1995.
Certifications
American Board of Anesthesiology, Certificate 27172, 1996.
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Selected Publications

Johansson JS, Solt K, Reddy KS: Binding of the general anesthetics chloroform and 2,2,2-trichloroethanol to the hydrophobic core of a four-a-helix bundle protein. Photochem Photobiol 77: 20-26, 2003.

Johansson JS, Manderson GA: Aromatic amino acid side-chain structure dictates halothane binding energetics. Alcohol Clin Exp Res 2003 Notes: in press.

Manderson GA, Michalsky SJ, Johansson JS: Effects of alanine-to-valine substitutions on the binding of halothane and chloroform to a four-a-helix bundle. Biophys J 2003 Notes: in press.

Johansson JS: Noninactivating tandem pore domain potassium channels as attractive targets for general anesthetics. Anesth Analg 2003 Notes: in press.

Chan K, Meng QC, Johansson JS, Eckenhoff RG: Low-affinity analytical chromatography for measuring inhaled anesthetic binding to isolated proteins. Anal Biochem 301: 3008-313, 2002.

Solt K, Johansson JS: Binding of the active metabolite of chloral hydrate, 2,2,2-trichloroethanol, to serum albumin demonstrated using tryptophan fluorescence quenching. Pharmacology 24: 152-159, 2002.

Chapeaurouge A, Johansson JS, Ferreira ST: Folding of a de novo designed four-helix bundle protein. J Biol Chem 277: 16478-16483, 2002.

Manderson GA, Johansson JS: The role of aromatic side chains in the binding of volatile general anesthetics to a four-a-helix bundle. Biochemistry 41: 4080-4087, 2002.

Meng QC, Johansson JS, Eckenhoff RG: A chromatographic approach to the determination of relative drug membrane permeability. J Chromatogr B Biomed Appl 744: 89-95, 2002.

Johansson JS, Manderson GA: The role of aromatic side chains in the binding of volatile general anesthetics to a four-alpha-helix bundle. Biophys J 82: A1617, 2002.

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Last updated: 03/02/2007
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