Department of Anesthesiology and Critical Care

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Max B. Kelz, MD PhD

David E. Longnecker Associate Professor of Anesthesiology and Critical Care
Member, Mahoney Institute of Neurological Sciences, University of Pennsylvania
Member, Penn Genomics Institute, University of Pennsylvania
Member, Institute for Translational Medicine and Therapeutics
Member, Center for Sleep and Circadian Neurobiology, University of Pennsylvania
Chair of Admissions, Department of Neuroscience MD PhD program, University of Pennsylvania, Perelman School of Medicine
MSTP Program Advisor, University of Pennsylvania
Director for Research Education, Department of Anesthesiology, University of Pennsylvania, Perelman School of Medicine
Member, Committee on Appointments and Promotions, Department of Anesthesiology, University of Pennsylvania
Education Council Member, Children's Hospital of Philadelphia, Department of Anesthesiology
Ombudsman, Department of Anesthesiology and Critical Care, University of Pennsylvania
Department: Anesthesiology and Critical Care

Contact information
3620 Hamilton Walk,
John Morgan Building - Room 334
Philadelphia, PA 19104
Office: 215 573-8208
Fax: 215 349-5078
Lab: 215 898-8929
Graduate Group Affiliations
BS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
MS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
PhD (Neuroscience)
Yale University, 1999.
MD (Medicine)
Yale University, 2000.
Post-Graduate Training
Transitional Internship, University of Pennsylvania Perelman School of Medicine, 2000-2001.
Resident in Anesthesiology, University of Pennsylvania Perelman School of Medicine, 2001-2004.
Diplomat, National Board of Medical Examiners, 2001.
Diplomat, American Board of Anesthesiology, 2005.
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Description of Research Expertise

Molecular Mechanisms of Anesthetic Action
Neurobiology of Sleep Wake Regulation
Mouse Genetics
Molecular Biology
Anesthetic pharmacology

Description of Clinical Expertise


Selected Publications

Richardson Andrew G, Liu Xilin, Weigand Pauline K, Hudgins Eric D, Stein Joel M, Das Sandhitsu R, Proekt Alexander, Kelz Max B, Zhang Milin, Van der Spiegel Jan, Lucas Timothy H: Hippocampal gamma-slow oscillation coupling in macaques during sedation and sleep. Hippocampus Jul 2017.

Blain-Moraes Stefanie, Tarnal Vijay, Vanini Giancarlo, Bel-Behar Tarik, Janke Ellen, Picton Paul, Golmirzaie Goodarz, Palanca Ben J A, Avidan Michael S, Kelz Max B, Mashour George A: Network Efficiency and Posterior Alpha Patterns Are Markers of Recovery from General Anesthesia: A High-Density Electroencephalography Study in Healthy Volunteers. Frontiers in human neuroscience 11: 328, 2017.

Maier Kaitlyn L, McKinstry-Wu Andrew R, Palanca Ben Julian A, Tarnal Vijay, Blain-Moraes Stefanie, Basner Mathias, Avidan Michael S, Mashour George A, Kelz Max B: Protocol for the Reconstructing Consciousness and Cognition (ReCCognition) Study. Frontiers in human neuroscience 11: 284, 2017.

Wasilczuk AZ, Proekt A, Kelz MB, McKinstry-Wu AR.: High-density Electroencephalographic Acquisition in a Rodent Model Using Low-cost and Open-source Resources. J Vis Exp. 117: e54908, Nov 2016.

Erickson RL, Terzi MC, Jaber SM, Hankenson FC, McKinstry-Wu A, Kelz MB, Marx JO.: Intraperitoneal Continuous-Rate Infusion for the Maintenance of Anesthesia in Laboratory Mice (Mus musculus). J Am Assoc Lab Anim Sci. 55(5): 548-57, September 2016.

Gardner B, Strus E, Meng QC, Coradetti T, Naidoo NN, Kelz MB, Williams JA.: Sleep Homeostasis and General Anesthesia: Are Fruit Flies Well Rested after Emergence from Propofol? Anesthesiology 124(2): 404-16, Feb 2016.

Drobish JK, Kelz MB, DiPuppo P, Cook-Sather SD: Case report: Emergence delirium with transient associative agnosia and expressive aphasia reversed by flumazenil in a pediatric patient. Anesthesia & Analgesia Case Reports 11(4): 148-150, June 2015.

McCarren HS, Chalifoux MR, Han B, Moore JT, Meng QC, Baron-Hionis N, Sedigh-Sarvestani M, Contreras D, Beck SG, Kelz MB: α2-Adrenergic Stimulation of the VLPO Destabilizes the Anesthetic State. Journal of Neuroscience 34(49): 16385-96, Dec 2014.

Han B, McCarren HS, O'Neill D, Kelz MB: Distinctive Recruitment of Endogenous Sleep-promoting Neurons by Volatile Anesthetics and a Nonimmobilizer. Anesthesiology 121(5): 999-1009, Nov 2014.

Jaber SM, Hankenson FC, Heng K, McKinstry-Wu A, Kelz MB, Marx JO: Dose regimens, variability, and complications associated with using repeat-bolus dosing to extend a surgical plane of anesthesia in laboratory mice. J Am Assoc Lab Anim Sci. 53(6): 684-91, Nov 2014.

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Last updated: 10/10/2017
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