Max Kelz, MD PhDAssistant Professor of Anesthesiology and Critical Care
Member
Member
Member
Member
Department: Anesthesiology and Critical Care
Contact information
3620 Hamilton Walk,
John Morgan Buidling room 334 Philadelphia, PA 19104
Office: 215 662-3713
Fax: 215 349-5078 Email: kelzma@uphs.upenn.edu
Graduate Group Affiliations
Links
Kelz homepage, Mahoney Institute of Neurological Sciences Max Kelz homepage, Department of Anesthesiology and Critical Care University of Pennsylvania School of Medicine
Education:
BS (Molecular Biophysics and Biochemistry) Yale University, 1993. MS (Molecular Biophysics and Biochemistry) Yale University, 1993. PhD (Neuroscience) Yale University, 1999. MD (Medicine) Yale University, 2000.
Post-Graduate Training
Intern, University of Pennsylvania, Presbyterian Medical Campus, 2000-2001. Resident , University of Pennsylvania, Department of Anesthesia, 2001-2004.
Certifications
Permanent linkDiplomat, National Board of Medical Examiners, 2001. Diplomat, American Board of Anesthesiology, 2005. Description of Research ExpertiseMolecular Mechanisms of Anesthetic ActionNeurobiology of Sleep Wake Regulation Mouse Genetics Molecular Biology Anesthetic pharmacology Description of Clinical ExpertiseAnesthesiologySelected PublicationsBianchi SL, Caltagarone MS, Oddo S, LeFerla FM, Eckenhoff RG, Kelz MB: Inhaled Anesthetic Potency in Aged Alzheimer's Mice. Anesthesia and Analgesia in press, December 2009.Gompf H, Chen J, Sun Y, Yanagisawa M, Aston-Jones G, Kelz MB : Halothane-induced Hypnosis Is Not Accompanied by Inactivation of Orexinergic Output in Rodents Anesthesiology 111(5): 1001-1009, November 2009. Kelz MB; Sun Y; Chen J; Meng QC; Moore JT; Veasey SC; Dixon S; Thornton M; Funato H; Yanagisawa M.: An Essential Role for Orexins in Emergence from General Anesthesia. Proceedings of the National Academy of Sciences 105(4): 1309-1314, January 2008 Notes: commentary in PNAS 2008 v.105 p.1100 Zhu, Y., Fenik, P., Zhan, G., Mazza, E., Kelz, M., Aston-Jones, G., Veasey, S. C.: Selective loss of catecholaminergic wake active neurons in a murine sleep apnea model. Journal of Neuroscience 27(37): 10060-71, Sep 12 2007. Leach NT, Sun Y, Michaud S, Zheng Y, Ligon KL, Ligon AH, Sander T, Korf BR, Lu W, Harris DJ, Gusella JF, Maas RL, Quade BJ, Cole AJ, Kelz MB, Morton CC.: Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice. American Journal of Human Genetics 80(4): 792-799, April 2007. Sun Y, Chen J, Pruckmayr G, Baumgardner JE, Eckmann DM, Eckenhoff RG, Kelz MB: High throughput modular chambers for rapid evaluation of anesthetic sensitivity. BMC Anesthesiology. Biomed Central, 6(1): 13, November 2006. Zachariou V., Bolanos CA., Selley DE., Theobald D., Cassidy MP., Kelz MB., Shaw-Lutchman T., Berton O., Sim-Selley LJ., Dileone RJ., Kumar A., Nestler EJ.: An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nature Neuroscience 9(2): 205-11, Feb 2006. Chen J., Kelz MB., Zeng G., Steffen C., Shockett PE., Terwilliger G., Schatz DG., Nestler EJ.: Inducible, reversible hair loss in transgenic mice. Transgenic Research 11(3): 241-7, Jun 2002. Sakai N., Thome J., Newton SS., Chen J., Kelz MB., Steffen C., Nestler EJ., Duman RS.: Inducible and brain region-specific CREB transgenic mice. Molecular Pharmacology 61(6): 1453-64, Jun 2002. Sims NA., Sabatakos G., Chen JS., Kelz MB., Nestler EJ., Baron R.: Regulating DeltaFosB expression in adult Tet-Off-DeltaFosB transgenic mice alters bone formation and bone mass. Bone 30(1): 32-9, Jan 2002.
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