Department of Anesthesiology and Critical Care

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Christopher G. Ward, MD

Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care

Contact information
The Children's Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
34th Street and Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-0581
BA (Medicine)
University of Pennsylvania, 2000.
MD (Biology)
Jefferson Medical College, 2004.
Post-Graduate Training
Transitional Year Internship: with elective focuses in Surgery, Cardiology, Pulmonology, Neonatal Intensive Care Unit, Pediatrics and Anesthesia, Western Pennsylvania Hospital, Pittsburgh, PA, 2004-2005.
Resident, Anesthesiology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2005-2008.
Fellowship, Pediatric Anesthesiology, The Children's Hospital of Philadelphia, Philadelphia, PA, 2008-2009.
Locum Tenens, Anesthetic MOSS, Northland DHB, Whangerei Hospital, Whangarei, New Zealand, 2009-2010.
American Board of Anesthesiology- Pediatric Anesthesiology, 2013.
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Description of Clinical Expertise

Dr. Ward's clinical areas of expertise are in pediatric neuroanesthesia, advanced airway modalities for difficult pediatric airways, and the anesthesia care of patients with epidermolysis bullosa.

Description of Research Expertise

Dr. Ward investigates anesthetic induced neurotoxicity in the developing brain using rodent models. His lab examines both histopathological changes in the brain as well as learning and behavior outcomes associated with anesthetic drug exposure in neonatal and juvenille rodents. He also is involved in 2 clinical trials examining the effects of anesthesia on NIRS output and the TREX study evaluating dexmedetomidine and remifentanyl combined with caudal analgesia for urologic procedures.

Selected Publications

Jacob Dubroff, Robert Doot, Chris Ward, Jenny Cai, Hsiaoju Lee, Erin Schubert, Shihong Li, Catherine Hou, Regan Sheffer, Alex Schmitz and Robert Mach : First-in-Human Dynamic PET Brain Imaging of [18F] Fluortriopride, a Dopamine D3 Receptor Selective Radiotracer. 11th International Symposium on Functional NeuroReceptor Mapping of the Living Brain July 2016.

Ward CG, Eckenhoff RG: Neurocognitive adverse effects of anesthesia in adults and children: Gaps in knowledge. Drug Safety 2016 Notes: In Press.

Ward, CG, Hogan, KJ, Eckenhoff RG: Potential Adverse Effects of Anesthesia in Children. JAMA 314(4): 408-409, 2015.

Ward CG, Hines SJ, Maxwell LG, McGowan FX, Sun LS: Neurotoxicity, general anesthesia in young children, and a survey of current pediatric anesthesia practice at US teaching institutions. Paediatr Anaesth 26(1): 60-65, 2015.

Hofacer RD*, Meng D*, Ward CG*, Bernadin J, Hughes EA, Jiang C, Danzer SC, Loepke AW: Cell-age specific vulnerability of neurons to anesthetic toxicity. Annals of Neurology 73(6): 695-704, 2013 Notes: *co-first authors.

Istaphanous GK, Ward CG, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW: Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex. Anesthesia and Analgesia 116(4): 845-854, 2013.

Ward CG, Loepke AW: Anesthetics and sedatives: Toxic or protective for the developing brain? Pharmacological Research 65(3): 271-274, 2011.

Ward CG, Wei H: Multiples of minimal alveolar concentrations of volatile agents are not necessarily equipotent. Anesthesiology 114(1): 221-222, 2011.

Liang G*, Ward CG*, Peng J, Zhao Y, Huang B, Wei H : Isoflurane causes greater neurodegeneration than an equivalent exposure of sevoflurane in the developing brain of neonatal mice. Anesthesiology 112: 1325-1334, 2010 Notes: *Co-first authors.

Istaphanous G, Ward CG, Loepke AW: The impact of the perioperative period on neurocognitive development, with a focus on pharmacological concerns. Best Practice and Research Clinical Anaesthesiology 24(3): 433-449, 2010.

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Last updated: 04/18/2016
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