Department of Anesthesiology and Critical Care

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Francis X. McGowan, Jr., MD

Professor of Anesthesiology and Critical Care
Department: Anesthesiology and Critical Care

Contact information
Department of Anesthesiology and Critical Care Medicine
The Children's Hospital of Philadelphia
34th Street & Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-4520
Fax: 215-590-1415
Education:
BA (Biochemistry)
Brown University, 1979.
MD (Medicine)
Duke University School of Medicine, 1983.
Post-Graduate Training
Post Graduate Research Fellow in Cardiology, Duke University, Durham, NC, 1983-1983.
Intern Pediatrics, Yale-New Haven Hospital, New Haven, CT, 1983-1984.
Resident, Pediatrics, Yale-New Haven Hospital, New Haven, CT, 1984-1986.
Acting Chief Resident, Pediatrics Outpatient Department, Yale-New Haven Hospital, New Haven, CT, 1984-1986.
Resident, Anesthesiology, Yale-New Haven Hospital, New Haven, CT, 1986-1988.
Specialized Year in Pediatric/Pediatric Cardiac Anesthesiology, Yale-New Haven Hospital, New Haven, CT, 1988-1989.
Research Fellow, Cardiovascular Pathology, Yale University School of Medicine, Departments of Anesthesiology and Pathology, New Haven, CT, 1988-1989.
Chief Resident in Anesthesiology, Yale-New Haven Hospital, New Haven, CT, 1988-1989.
Certifications
American Board of Anesthesiology, 1990.
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Selected Publications

Kheir JK, Thomson L, Polizzotti BD, Wilking JN, Graham DA, Bell DC, O'Connell D, McGowan FX. : Oxygen carrying capacity and release by lipidic microparticles in vitro and in vivo: structure-activity determinants. Biomaterials 2013; (in press).

He H, Campbell P, Kawata M, Poutias DN, Friehs I, Hickey J, Gussoni E, McGowan FX: Load-induced mitochondrial reactive oxygen species production promotes electron transport complex dysfunction, mitochondrial damage, and right ventricular failure. Am J Physiol 2013; (in press).

Graham EM, Atz AM, McHugh KE, Butts RJ, Baker NL, Stroud RE, Deardorff RL, Reeves ST, Bradley SM, McGowan FX, Spinale FG: Preoperative steroid treatment does not improve markers of inflammation following cardiac surgery in neonates J Am Coll Cardiol 2013.

Graham EM, Taylor SN, Zyblewski SC, Wolf B, Bradley SM, Hollis BW, McGowan FX, Atz AM: Vitamin D status in neonates undergoing cardiac operations: relationship to cardiopulmonary bypass and association with outcomes. J Pediatr 162(4): 823-826, 2013.

Kheir JK, Thomson L, Polizzotti BD, Wilking JN, Graham DA, Bell DC, O'Connell D, McGowan FX: Bulk manufacture of concentrated oxygen gas-filled microparticles for intravenous oxygen delivery. Adv Healthc Mater 2013;2:1131-41. Adv Healthc Mater (2), 1131-1141, 2013.

Bartholoma MD, He H, Pacak C, Dunning P, Fahey FH, McGowan FX, Cowan DB, Treves ST, Packard A: Biological characterization of F-18-labeled rhodamine B, a potential positron emission tomography perfusion tracer. Nucl Med Biol 2013.

Xiong D,He H, Strauss AW, James J, Tokunaga C, Powers C, Osinska S, Towbin JA, Purevjav J, Balschi JA McGowan FX: Cardiac-specific VLCAD deficiency induces dilated cardiomyopathy and cold intolerance Am J Physiol Heart Circ Physiol February, 2013.

He H, Poutias DN, Favre E, Balschi JA, McGowan FX: Upregulation of NOX4 triggers mitochondrial dysfunction during the progression of infant right ventricular hypertrophy. Circulation 126: A13534, 2012.

Graham EM. Atz AT, Gillis G, DeSantis S, Haney AL, Deardorff RL; Uber WE, Reeves RT, McGowan FX; Bradley SM, Spinale FG : Differential effects of aprotonin and tranexamic acid on outcomes and cytokine profiles in pediatric cardiac surgery. J Thorac Cardiovasc Surg 143: 1069-1076, 2012.

Mehta NM, Costello JM, Bechard LJ, Johnson VM, Zurakowski D, McGowan FX, Laussen PC, Duggan CP: Resting energy expenditure after Fontan surgery in children with single-ventricle heart defects. J Parenter Enteral Nutr 36: 685.692, 2012.

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Last updated: 04/10/2014
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