Department of Neurology

Department of Neurology
faculty photo

Roy Hoshi Hamilton, MD, MS

Assistant Professor of Neurology
Associate Director, Clinical Neurosciences Training Program (CNST), Perelman School of Medicine, University of Pennsylvania
Faculty, Center for Cognitive Neuroscience, University of Pennsylvania, University of Pennsylvania
Director, Laboratory for Cognition and Neural Stimulation, University of Pennsylvania, University of Pennsylvania
Faculty, Center for Neuroscience and Society, University of Pennsylvania, University of Pennsylvania
Assistant Dean of Diversity and Inclusion, Perelman School of Medicine, University of Pennsylvania, University of Pennsylvania
Department: Neurology

Contact information
Goddard Laboratories, Room 518
University of Pennsylvania
3710 Hamilton Walk
Philadelphia, PA 19104
Office: 215-573-7065
Fax: 215-898-1982
Graduate Group Affiliations
BA (Psychology, magna cum laude)
Harvard University, 1995.
MD (Medicine, cum laude)
Harvard Medical School, 2001.
MS (Health Sciences and Technology)
Massachusetts Institute of Technology , 2001.
Post-Graduate Training
Intern in Internal Medicine, University of California School of Medicine, Los Angeles, 2001-2002.
Resident in Neurology, University of Pennsylvania, 2002-2005.
Fellow in Cognitive Neurology, University of Pennsylvania, 2005-2007.
American Board of Psychiatry and Neurology, 2006.
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Description of Research Expertise

My research focus is on the characteristics and limits of functional neuroplasticity in the adult human brain. I investigate how the brain reorganizes itself in response to injury, and whether or not it is possible to enhance the brain’s potential for reorganization in order to speed rehabilitation using noninvasive electrical or magnetic brain stimulation. A second area of interest for me is on the use of noninvasive brain stimulation to elucidate and enhance mechanisms of cognition in healthy individuals, and the biological, social, and ethical implications of neural enhancement.

Description of Clinical Expertise

I principally treat patients suffering from dementia. I also have expertise in evaluating and treating patients with cognitive deficits following stroke.

Description of Other Expertise

I am deeply interested in medical education. I am heavily involved in medical student education in Neurology at the University of Pennsylvania School of Medicine, and I am the faculty director of the University of Pennsylvania School of Medicine Pipeline Program, multi-tiered neuroscience education program for inner-city high schools in Philadelphia.

Selected Publications

Woods, A.J., Vaughn, B., Sacchetti, D., Gervits, F., Hamilton, R. : Effects of electrode drift in transcranial direct current stimulation. Brain Stimulation 8(3): 515-519, May 2015.

Shah-Basak, P.P. Norise, C. Garcia, G. Torres, J. Faseyitan, O. Hamilton, R.H.: Individualized treatment with transcranial direct current stimulation in patients with chronic non-fluent aphasia due to stroke. Frontiers in Human Neuroscience(9), 201, Apr 2015.

Gill, J., Shah-Basak, P P., Hamilton, R.: It's the thought that counts: Examining the task-dependent effects of transcranial direct current stimulation on executive function. Brain Stimulation Mar 2015.

Wood, A.J., Hamilton, R.H., Kranjec, A., Minhas, P., Bikson, M., Yu, J., Chatterjee, A. : Space, time, and causality in the human brain. NeuroImage 92: 285-97, May 2014.

Kraemer,D.J. Hamilton,R. Messing,S.B. DeSantis, J.H. Thompson-Schill, S.L.: Cognitive style, cortical stimulation, and the conversion hypothesis Frontiers in Human Neuroscience 8: 15, Jan 2014.

Hamilton, R.H., Wiener, M., Drebing, D.E., Coslett, H.B.: Gone in a flash: manipulation of audiovisual temporal integration using transcranial magnetic stimulation. Frontiers in Psychology: Perception Science Sept 2013.

Garcia, G., Catherine, N., Faseyitan, O., Naeser, M.A., Hamilton, R.H.: Utilizing repetitive transcranial magnetic stimulation to improve language function in stroke patients with chronic non-fluent aphasia. Journal of Visual Experimentation(77), July 2013.

Mesquita, R.C., Faseyitan, O.K., Turkeltaub, P.E., Buckley, E.M., Thomas, A., Kim, M.N., Greenberg, J.H., Detre, J.A., Yodh, A.G., Hamilton, R.H.: Blood flow and oxygenation changes due to low-frequency repetitive transcranial magnetic stimulation of the cerebral cortex. Journal of Biomedical Optics 18(6): 67006, June 2013.

Chrysikou E.G., Hamilton R.H., Coslett H.B., Datta A., Bikson M., Thompson-Schill S.L.: Noninvasive transcranial direct current stimulation over the left prefrontal cortex facilitates cognitive flexibility in tool use. Cognitive Neuroscience 4(2): 81-89, June 2013.

Medina, J. Beauvais, J. Datta, A. Bikson, M. Coslett, H B. Hamilton, R H.: Transcranial direct current stimulation accelerates allocentric target detection. Brain Stimulation 6(3): 433-9, May 2013.

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Last updated: 11/19/2015
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