Department of Neurology

Department of Neurology
faculty photo

Hongyu Sun, MD, PhD

Research Assistant Professor of Neurology
Department: Neurology

Contact information
Perelman School of Medicine, University of Pennsylvania
Department of Neurology
265 Clinical Research Building
413 Curie Boulevard
Philadelphia, PA 19104
Lab: 215-898-0552
Education:
MD (Medicine)
Tianjin Medical University, Tianjin, China, 1997.
MSc (Neuroscience and Neurosurgery)
Tianjin Medical University, Tianjin, China, 2002.
PhD (Neuroscience)
Carleton University, Ottawa, Canada, 2008.
Post-Graduate Training
Intern, Tianjin General Hospital, Tianjin, China, 1996-1997.
Resident, Jixian Hospital, Department of Neurosurgery, Tianjin, China, 1997-1999.
Research Assistant, Tianjin Neurological Institute, Tianjin Medical University, Tianjin, China , 1999-2002.
Resident/Fellow, Tianjin General Hospital, Department of Neurosurgery, Tianjin, China, 1999-2002.
Research Fellow, Tianjin Neurological Institute, Tianjin Medical University, Tianjin, China , 2002-2003.
Research Assistant, Institute of Neuroscience, Carleton University, Ottawa, ON , 2003-2008.
Postdoctoral Research Fellow, Institute of Neuroscience, Carleton University, Ottawa ON , 2008-2009.
Postdoctoral Research Fellow, Department of Neurology, Children's Hospital Boston and Harvard Medical Center, Boston, MA , 2009-2012.
Postdoctoral Research Fellow, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA , 2012-present.
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Selected Publications

Cleary R, Sun H, Huynh T, Manning SM, Li Y, Rotenberg A, Talos DM, Jackson M, Rakhade SN, Berry G, Jensen FE: Synergistic Anticonvulsant Efficacy of Combination Phenobarbital and NKCC1 Inhibitor Bumetanide Treatment in a Rat Model of Neonatal Seizures. PLoS one Page: 10.1371/journal.pone.0057148, 2013.

Sun H, Kosaras B, Klein PM, Jensen FE: mTORC1 Activation Negatively Regulates PLK2 Mediated Homeostatic Compensation Following Neonatal Seizures. PNAS 110(13): 5199-5204, 2013.

Sun H, Zhou C, Klein P, Jensen FE: Alteration of Extrasynaptic NMDA Receptors Following Early-Life Seizures. Society for Neuroscience Meeting, New Orleans, LA 2012 Notes: Oral Presentation.

Kosaras B, Klein P, Cleary R, Sun H, Jensen FE: NKCC1 Inhibitor Bumetanide Attenuates The Vigabatrin-Induced Retina Toxicity. American Epilepsy Society, San Diego 2012 Notes: Oral Presentation.

Talos DM, Sun H, Zhou X, Fitzgerald E, Jackson M, Lan V, Joseph A, Jensen FE: Inhibition of the Mammalian Target of Rapamycin (mTORC1) Prevents Later Life Epilepsy and Autism-like Behavior Following Early Life Seizures. PLoS One. (Sun is the co-first author) 7(5): e35885, 2012.

Sun H, Goto J, Talos DM, Kansas B, Klein PM, Kwiatkowski DJ, Jensen FE: Epileptogenesis in TSC: Contribution from GABAa Receptor Mediated Excitation? American Epilepsy Society Meeting, San Diego, Ca 2012 Notes: Oral Presentation.

Talos, DM, Sun H, Kosaras B, Joseph A, Folkerth RD, Poduri A, Madsen JR, Black PM, Jensen FE: Altered Inhibition in Tuberous Sclerosis and Type IIb Cortical Dysplasia. Ann Neurol 71 (4): 539-551, 2012.

Rakhade SN, Fitzgerald EF, Klein PM, Zhou C, Sun H, Huganir RL, Jensen FE: Glutamate Receptor 1 Phosphorylation at Serine 831 and 845 Modulates Seizure Susceptibility and Hippocampal Hyerexcitability Following Early Life Seizures. Journal of Neuroscience 32(49): 17800-17812, 2012.

Sun H, Kosaras B, Klein P, Jensen FE: PLK2-Mediated Homeostatic Regulation of Neural Excitability Following Early Life Seizures in Rats. American Epilepsy Society. Baltimore, MD 2011 Notes: Poster.

Sun H, Talos DM, Kosaras B, Fitzgerald E, Jackson MC, Kwiatkowski DJ: Enhanced Excitatory Synaptic Function in Cortical Cicuits in a TSC Mouse Model. Annual Meeting of the Society for Neuroscience. Washington, DC 2011 Notes: Poster.

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Last updated: 10/17/2013
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