Steven Brem, M.D.
Professor of Neurosurgery at the Hospital of the University of Pennsylvania
Department: Neurosurgery
Contact information
3400 Spruce Street, 3rd Floor Silverstein
Department of Neurosurgery
Philadelphia, PA 19104
Department of Neurosurgery
Philadelphia, PA 19104
Office: (215) 662-7854
Email:
stevenbrem@gmail.com
stevenbrem@gmail.com
Education:
BA (Magna Cum Laude)
Rutgers University, 1968.
MD (Medicine - Cum Laude)
Harvard Medical School, 1972.
BA (Magna Cum Laude)
Rutgers University, 1968.
MD (Medicine - Cum Laude)
Harvard Medical School, 1972.
Post-Graduate Training
Surgery , Massachusetts General Hospital - Intership , 1972-1973.
Neurosurgery, Massachusetts General Hospital - Residency , 1973-1981.
Clinical Associate, Oncology, Laboratory of Pathophysiology, National Cancer Institute - Postdoctoral Research, 1974-1976.
Neurosurgery, New York Hospital, Cornell Medical Center - Fellowship , 1979-1980.
Surgery , Massachusetts General Hospital - Intership , 1972-1973.
Neurosurgery, Massachusetts General Hospital - Residency , 1973-1981.
Clinical Associate, Oncology, Laboratory of Pathophysiology, National Cancer Institute - Postdoctoral Research, 1974-1976.
Neurosurgery, New York Hospital, Cornell Medical Center - Fellowship , 1979-1980.
Certifications
National Board of Medical Examiners, 1973.
Royal College of Physicians and Surgeons of Canada, Neurosurgery Fellowship , 1982.
Province of Quebec, Neurosurgery , 1982.
American Board of Neurological Surgery, 1983.
Permanent linkNational Board of Medical Examiners, 1973.
Royal College of Physicians and Surgeons of Canada, Neurosurgery Fellowship , 1982.
Province of Quebec, Neurosurgery , 1982.
American Board of Neurological Surgery, 1983.
Description of Clinical Expertise
Complex Brain Tumor Surgery; Surgery of Intrinsic and Metastatic Brain Tumors; Pituitary Tumors; Acoustic Neuromas; Meningiomas; Skull Base Surgery; Brain Mapping; Health Outcomes; Evidence-Based Medicine;Description of Research Expertise
Angiogenesis, Neuro-Oncology, Translational Drug Discovery, Personalized Medicine, Genomics, Biomarkers, Experimental Therapeutics, Brain Mapping, Health Outcomes, Brain Metastases, Clinical Guidelines, Clinical Pathways, Glioma Invasion, Targeted Brain Tumor TherapiesSelected Publications
Egan KM, Thompson RC, Nabors LB, Olson JJ, Brat DJ, LaRocca RV, Brem S, Moots PL, Madden MH, Browning JE, Chen AY: Cancer susceptibility variants and the risk of adult glioma in a US case-control study. J Neurooncol Jan 2011 Notes: Epub ahead of print.Brem S, Jain S, commentary to: Yang X, Cao W, Zhou J, Zhang W, Zhang X, Lin W, Fei Z, Lin H, Wang B: 14-3-zeta positive expression is associated with a poor prognosis in patients with glioblastoma. Neurosurgery 68: 938, 2011.
Wong ET, Brem S: Taming glioblastoma by targeting angiogenesis: Three years later. J Clin Oncol 29: 124-126, 2011.
Brem S, commentary to: Velez AM, Friedman WA: Disseminated intravascular coagulation during resection of a meningioma. Neurosurgery 68: E1169, 2011.
Brem S, Wong E: Angiogenesis and brain tumors: Molecular targets and molecular scalpels. Youmans Neurological Surgery, 6th edition. Winn HR (eds.). Elsevier, Philadelphia, Page: 1151-1171, e271-277, 2011 Notes: Chap. 104.
Brem S, Jain S, commentary to: Elliott RE, Rush SC, Morsi A, Mehta N, Spriet J, Narayana A, Donahue B, Parker EC, Golfinos JG: Local control of newly diagnosed and distally recurrent, low-volume brain metastases with fixed-dose (20 Gy) gamma knife radiosurgery. Neurosurgery 68: 931, 2011.
Brem SS, Bierman PJ, Brem H, Butowski N, Chamberlain MC, Chiocca EA, Deangelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hess D, Junck L, Linette GP, Loeffler JJ, Maor MH, Michael M, Moots P, Morrison T, Mrugala M, Nabors LB, Newton HB, Portnow J, Raiser JJ, Shrieve DC, Sills AK Jr., Vrionis FD, Wen PY.: Central nervous system cancers. J Natl Compr Canc Netw 9 (4): 352-400, 2011.
Brem S, Jain S, commentary to: Forster MT, Hattingen E, Senft C, Gasser T, Seifert V, Szelényi A: Navigated transcranial magnetic stimulation and functional magnetic resonance imaging: Advanced adjuncts in preoperative planning for central region tumors. Neurosurgery 68: 1324-1325, 2011.
Wong ET, Gautam S, Malchow C, Lun M, Pan E, Brem S: Bevacizumab for recurrent glioblastoma: a meta-analysis. J Natl Compr Cancer Netw 9 (4): 403-407, 2011.
Murphy SF, Banasiak M, Yee G-T, Wotoczek-Obadia M, Malafa M, Rojiani MV, Rojiani AM, Tofilon P, Henderson F, Djakiew D, Jung M, Forsyth PA, Senger DL, Brem S: Ibuprofen, an inhibitor of angiogenesis, enhances radiosensitivity and suppresses glioma invasion: Role of p75NTR and VEGF. Proc Amer Assoc Cancer Res 2010 Notes: (abstr. #5271).
