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Timothy H Lucas Jr., M.D., Ph.D.

Assistant Professor of Neurosurgery
Attending Neurosurgeon, Pennsylvania Hospital
Director, Translational Neuromodulation Laboratory, Department of Neurosurgery, University of Pennsylvania
Associate Director, Center for Neuroengineering & Therapeutics, University of Pennsylvania
Attending Neurosurgeon , Penn Presbyterian Medical Center
Attending Neurosurgeon, Children's Hospital of Philadelphia
Surgical Director, Penn Epilepsy Center, The Hospital of the University of Pennsylvania
Director, Neurosurgery Gene Therapy Program, Perelman School of Medicine, School of Engineering & Applied Science (SEAS), University of Pennsylvania
Director, Laser Neurosurgery Center, Perelman School of Medicine, University of Pennsylvania
Mack Technology Fellow, Wharton Business School, University of Pennsylvania
Department: Neurosurgery

Contact information
3400 Spruce Street
3rd Floor Silverstein
Philadelphia, PA 19104
Office: 215-615-0578
Fax: 215-349-5534
Lab: 215-746-1336
Graduate Group Affiliations
Education:
B.S. (Neurobiological Sciences & Psychobiology)
University of Florida, 1996.
M.D. (Medicine)
University of Florida, 2001.
Ph.D. (Physiology & Biophysics)
University of Washington, 2009.
MHCI (Health Care Innovation, Public Health and Health Policy)
University of Pennsylvania, 2018.
Post-Graduate Training
Intern in General Surgery, University of Washington, 2001-2002.
Resident in Neurological Surgery, University of Washington, 2002-2009.
Specialist Registrar in Neurological Surgery, St. George's National Healthcare Trust, London, England, UK, 2006-2007.
Chief Resident in Neurological Surgery, University of Washington, 2009-2010.
Fellow in Neurosurgical Oncology & Cerebrovascular Neurosurgery, University of Washington, 2010-2010.
Clinical Experience in Stereotactic & Functional Neurosurgery, University of California San Francisco, 2011-2011.
Fellow in Neurosurgical Oncology Brain Mapping, University of California San Francisco, 2011-2011.
Certifications
American Board of Neurological Surgery, 2016.
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Description of Clinical Expertise

Epilepsy Surgery
Temporal Lobectomy
Minimally invasive neurosurgery
Laser Neurosurgery
Neuromodulation
Endoscopic Surgery
Sports Neurosurgery
Cortisectomy / Topectomy
Corpus Callostomy / Functional Disconnection Surgery
Trigeminal neuralgia
Microvascular decompression
Stereotactic and Functional Neurosurgery
Movement Disorder Surgery (Parkinson's Disease, Essential Tremor, Dystonia)
Glioma Surgery (Low Grade, High Grade, Adult, Pediatric)
Insular Lesions
Brain Mapping (Speech, Motor, Sensory; cortical and subcortical)
Extraoperative Brain Mapping
Neuroprosthetics
Brain-machine interface / Brain-computer interface
Spine Disorders
Spinal Fusion
Skull base surgery
Brain Plasticity
Eloquent Cortex Lesions (motor, sensory, speech, visual cortex)
Traumatic brain and spine injury

Description of Research Expertise

Brain-machine interface / Brain-computer interface
Motor Cortex Functional Organization
Voluntary Movement
Speech and Language Organization
Cortical Plasticity
Basal Ganglia - Cortical Interactions
Cortical/Basal Ganglia Stimulation
Cortical Spike and Local Field Recording
Basal Ganglia Spike and Local Field Recording
Neuroprosthetics
Spinal Cord Stimulation and Mapping
Electromyography

Selected Publications

Chen H and TH Lucas: Advances in DBS surgery. Advances in Functional Neurosurgery, Thieme. Anderson, W (eds.). Thieme, 1(1), 6 2018.

Buch V, C Brandon, A Khambhati, A Richardson, BS Bassett, TH Lucas: "Increased dynamic modularity of the fronto-temporo-limbic network precedes enhanced task performance". American Association of Neurological Surgeons Annual Meeting, New Orleans 2018 Notes: Poster Presentation.

Ghenbot Y, A Richardson, X Liu, H Hao, S DeLuccia, G Boyek, J Van der Spiegel, TH Lucas: "Augmenting perception through electrical stimulation of adult somatosensory cortex" Association for Clinical and Translational Science, Annual Meeting, Washington D.C. 2018 Notes: Poster Presentation.

Mallela A, K Abdullah, AG Richardson, TH Lucas: Topical Vancomycin Reduces Surgical-Site Infections After Craniotomy: A Prospective, Controlled Study. Neurosurgery Dec 2017 Notes: [Epub Ahead of Print]

Richardson AG, X Liu, PK Weigand, ED Hudgins, JM Stein, S Das, A Proekt, MB Kelz, M Zhang, J Van der Spiegel: Hippocampal gamma slow oscillation coupling in macaques during sedation and sleep. Hippocampus 27(11): 1125-39, Nov 2017.

Lucas TH, X Liu, M Zhang, S Sritharan, I Planell, Y Ghenbot, S Torres, C Brandon, J Van der Spiegel, AG Richardson: Strategies for autonomous sensor-brain interfaces for closed loop sensory reanimation of paralyzed limbs. Neurosurgery 64(CN_Suppl_1)): 11-20, Sep 2017.

Ung H, B Litt, A Nanivadekar, C Cazares, L Kini, J Wagenaar, D Becker, M Kahana, TH Lucas, G Baltuch, M Sperling, A Sharan, K Davis: Interictal epileptiform activity outside the seizure onset zone impacts cognition. Brain 140(8): 2157-2168, Aug 2017.

Ezzyat Y, JF Burke, DF Levy, A Lyalenko, MR Sperling, AD Sharan, GA Worrell, MT Kucewicz, BC Jobst, KA Davis, TH Lucas, RE Gross, BC Lega, JM Stein, S Das, R Gorniak, DS Rizzuto, MJ Kahana: Direct Brain Stimulation Modulates Encoding States and Memory Performance in Humans. Current Biology 27(9): 1251-8, May 2017.

Attiah M, J De Vries, AG Richardson, TH Lucas: A rodent model of dynamic facial reanimation using functional electrical stimulation. Frontiers in Neuroscience 11: 193, Apr 2017 Notes: eCollection 2017.

Abdullah KG, Y Li, N Nayak, J Thawani, R Balu, TH Lucas: Long term utility and complication profile of open craniotomy for biopsy in patients with idiopathic encephalitis. J Clinical Neuroscience 37: 69-72, Mar 2017.

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Last updated: 01/19/2018
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