University of Pennsylvania Health System

Department of Ophthalmology

Ophthalmology Faculty

Maureen G. Maguire, PhD

faculty photo
Carolyn F. Jones Professor of Ophthalmology
Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, School of Medicine
Senior Scholar, Leonard Davis Institute for Health Economics, University of Pennsylvania, School of Medicine
Vice Chair for Clinical Research, Department of Ophthalmology, University of Pennsylvania, School of Medicine
Associate, Center for Public Health Initiatives, University of Pennsylvania
Department: Ophthalmology

Contact information
3535 Market Street, Suite 700
Philadelphia, PA 19104-3309
Graduate Group Affiliations
Education:
B.A. (Mathematics)
Rider College Summa cum laude, Honors in Mathematics, 1975.
Sc.M. (Biostatistics)
The Johns Hopkins University School of Hygiene and Public Health , 1977.
Ph.D. (Biostatistics)
The Johns Hopkins University School of Hygiene and Public Health , 1983.
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Description of Research Expertise

Dr. Maguire is Director of the Center for Preventive Ophthalmology and Biostatistics with the Department of Ophthalmology. Current research projects include:

1) directing the Coordinating Center for the NIH-funded Comparison of Age-related Macular Degeneration Treatments Trials, a multicenter, randomized clinical trial involving 1200 patients with choroidal neovascularization
2) screening for and treatment of eye conditions affecting preschool children
3) methodology in clinical research for ocular conditions including efficient study design and analysis of correlated data.

Dr. Maguire consults on many projects in vision science, both within and outside of the University.

Selected Publications

Moja L, Lucenteforte E, Kwag K, Bertele V, Campomori A, Chakravarthy U, Dickersin K, Evans J, Kodjikian L, Lindsley K, Loke Y, Maguire M, Martin DF, Mugelli A, Reeves BC, Rogers CA, Schmucker C, Subramanian ML, D’Amico R, Virgili G: Systemic safety of bevacizumab versus ranibizumab for neovascular age-related macular degeneration. Cochrane Database Syst Rev 9, Sep 15 2014 Notes: CD011230.

Pascual M, Huang J, Maguire MG, Kulp MT, Quinn GE, Ciner E, Cyert LA, Orel-Bixler D, Moore B, Ying G-S, , and the Vision in Preschoolers (VIP) Study Group: Risk factors for amblyopia in the Vision in Preschoolers (VIP) Study. Ophthalmology 121: 622-629, 2014 Notes: Epub 2013 Oct 18. [PMC 3943664]

Daniel E, Toth CA, Grunwald JE, Jaffe GJ, Martin DF, Fine SL, Ying G-S, Huang J, Winter K, Hagstrom SA, Maguire MG, the CATT Research Group: Risk of scar in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 121: 656-66, 2014 Notes: Epub 2013 Dec 4. [PMC 3943618]

Grunwald JE, Daniel E, Huang J, Ying G-S, Maguire MG, Toth CA, Jaffe GJ, Fine SL, Blodi B, Klein ML, Martin AA, Hagstrom SA, Martin DF, the CATT Research Group: Risk of geographic atrophy in Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 121: 150-161, 2014 Notes: Epub 2013 Sep 30, [PMC 3892560]

Hagstrom SA, Ying GS, Pauer GJ, Huang J, Maguire MG, Martin DF; CATT Research Group: Endothelial PAS Domain-Containing Protein 1 (EPAS1) Gene Polymorphisms and Response to Anti-VEGF Therapy in the Comparison of AMD Treatments Trials (CATT). Ophthalmology 2014 Notes: Epub 2014 May 6. PubMed PMID: 24813631.

Kim BJ, Ying GS, Huang J, Levy N, Maguire MG, and the CATT Research Group: Sporadic visual acuity loss in the Comparison of AMD Treatments Trials (CATT). Am J Ophthalmol 2014 Notes: Epub 2014 Apr 10.

Grunwald JE, Pistilli M, Ying GS, Daniel E, Maguire M, Xie D, Whittock-Martin R, Parker Ostroff C, Lo JC, Townsend RR, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman HI, Kusek JW, and the CRIC Study investigators: Retinopathy and progression of CKD: the Chronic Renal Insufficiency Cohort Study. Clin J Am Soc Nephrol 2014 Notes: Epub 2014 May 8.

Hagstrom SA, Ying G-S, Pauer GJT, Sturgill-Short GM, Huang J, Maguire MG, Martin DF: VEGFA and VEGFR2 gene polymorphisms and response to anti-vascular endothelial growth factor therapy in the Comparison of AMD Treatments Trials (CATT). JAMA Ophthalmology 132: 521-7, 2014 Notes: Epub 2014 Mar 20.

Kulp MT, Ying GS, Huang J, Maguire MG, Quinn GE, Ciner EB, Cyert LA, Orel-Bixler DA, Moore BD, and Vision In Preschoolers (VIP) Study Group : Accuracy of noncycloplegic retinoscopy, Retinomax Autorefractor and SureSight Vision Screener for detecting significant refractive errors. Invest Ophthalmol Vis Sci 2014 Notes: Epub 2014 Jan 30.

Ying G-S, Maguire M, Ciner E, Cyert L, Kulp MT, Quinn GE, Orel-Bixler D, Moore B, and the Vision in Preschoolers (VIP) Study Group: Prevalence of vision disorders by racial and ethnic group among children participating in Head Start. Ophthalmology 121: 630-6, 2014 Notes: Epub 2013 Oct 31.

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Last updated: 11/17/2014
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