Maureen G. Maguire, PhD
Carolyn F. Jones Professor of Ophthalmology
Associate Scholar, Center for Clinical Epidemiology and Biostatistics
Senior Scholar, Leonard Davis Institute for Health Economics
Vice Chair for Clinical Research, Department of Ophthalmology
Associate, Center for Public Health Initiatives
Department: Ophthalmology
Contact information
3535 Market Street, Suite 700
Philadelphia, PA 19104-3309
Philadelphia, PA 19104-3309
Office: 215-615-1501
Fax: 215-615-1531
Fax: 215-615-1531
Email:
maguirem@mail.med.upenn.edu
maguirem@mail.med.upenn.edu
Graduate Group Affiliations
Publications
Education:
B.A. (Mathematics)
Rider College Summa cum laude, Honors in Mathematics, 1975.
Sc.M. (Biostatistics)
The Johns Hopkins University School of Hygiene and Public Health , 1977.
Ph.D. (Biostatistics)
The Johns Hopkins University School of Hygiene and Public Health , 1983.
Permanent linkB.A. (Mathematics)
Rider College Summa cum laude, Honors in Mathematics, 1975.
Sc.M. (Biostatistics)
The Johns Hopkins University School of Hygiene and Public Health , 1977.
Ph.D. (Biostatistics)
The Johns Hopkins University School of Hygiene and Public Health , 1983.
Description of Research Expertise
Dr. Maguire is Director of the Center for Preventive Ophthalmology and Biostatistics with the Department of Ophthalmology. Current research projects include:1) directing the Coordinating Center for the NIH-funded Comparison of Age-related Macular Degeneration Treatments Trials, a multicenter, randomized clinical trial involving 1200 patients with choroidal neovascularization
2) screening for and treatment of eye conditions affecting preschool children
3) methodology in clinical research for ocular conditions including efficient study design and analysis of correlated data.
Dr. Maguire consults on many projects in vision science, both within and outside of the University.
Selected Publications
Ying G-S, Maguire MG, Alexander J, Martin RW, Antoszyk AN, Complications of Age-related Macular Degeneration Prevention Trial Research Group: Description of the AREDS 9-step severity scale applied to participants in CAPT. Arch Ophthalmol (in press) 2009.Mowry EM, Loguidice MJ, Daniels AB, Jacobs DA, Markowitz CE, Galetta SL, Nano-Schiav ML, Cutter GR, Maguire MG, Balcer LJ: Vision-related quality of life in multiple sclerosis: correlation with new measures of low and high-contrast letter acuity. Journal of Neurology, Neurosurgery & Psychiatry (in press) 2009.
Ying G-S, Maguire M, Liu C, Antoszyk A, Complications of Age-related Macular Degeneration Prevention Trial Research Group: Night Vision Symptoms and Progression of Age-related Macular Degeneration (AMD)in the Complications of AMD Prevention Trial. Ophthalmology 115: 1876-82, July 2008 Notes: PMID: 18672295.
Complications of Age-related Macular Degeneration Prevention Trial (CAPT) Research Group. (Writing team member; Director of the Coordinating Center): Risk Factors for Choroidal Neovascularization and Geographic Atrophy in the Complications of Age-related Macular Degeneration Prevention Trial. Ophthalmology 115: 1474-79, May 2008 Notes: PMID: 18502512.
Maguire MG, Alexander J, Fine SL, Complications of Age-related Macular Degeneration Prevention Trial (CAPT) Research Group: Characteristics of choroidal neovascularization in the Complications of Age-related Macular Degeneration Prevention Trial (CAPT). Ophthalmology 115: 1468-1473, May 2008 Notes: PMID: 18486222.
Maguire AM, Simonelli F, Pierce EA, Pugh EN, Mingozzi F, Bennicelli J, Banfi S, Marshall KA, Testa F, Serace EM, Rossi S, Lyubarsky A, Arruda VR, Konkle B, Stone E, Sun J, Jacobs J, Dell’Osso L, Hertle R, Ma J, Redmond TM, Zhu X, Hauck B, Zelenaia O, Shindler KS, Maguire MG, Wright JF, Volpe NJ, McDonnell JW, Auricchio A, High KA, Bennett J: Safety and efficacy of gene transfer for Leber’s congential amaurosis. N Engl J Med 358: 2240-8, 2008 Notes: PMID: 18441370.
Ying G-S, Maguire MG, Alexander J, Martin RW, Antoszyk AN, The CAPT Research Group: The AREDS 9-Step AMD Severity Scale Applied to Participants in the Complications of Age-related Macular Degeneration Prevention Trial (CAPT): Baseline Classification, Risk of Advanced AMD, and Longitudinal Path Analysis. Invest Ophthalmol Vis Sci 2008;49:ARVO E-Abstract 1762 2008.
Jefferys JL, Alexander J, Hiner CJ, Javornik NB, Smith RE, Bressler NM, Hawkins BS, Maguire MG: Reproducibility of gradings of retinal photographs in eyes with subfoveal choroidal neovascularization and age-related macular degeneration in the Macular Photocoagulation Study. Ophthalmic Epidemiology 15: 191-201, 2008.
Zaveri MS, Conger A, Salter A, Frohman TC, Galetta SL, Markowitz CE, Jacobs DA, Cutter GR, Ying G-S, Maguire MG, Calabresi PA, Balcer LJ, Frohman EM: Retinal imaging by laser polarimetry corroborates optical coherence tomography evidence of axonal degeneration in multiple sclerosis. Arch Neurol 65: 924-8, 2008 Notes: PMID: 18625859.
Umscheid CA, Maguire MG, Pines JM, Everett WW, Baren JM, Townsend RR, Mines D, Szyld D, Gross, R: Untreated hypertension and the emergency department: a chance to intervene? Acad Emerg Med 15: 529-36, 2008 Notes: PMID: 18616438.
