Juan E. Grunwald, MD
Professor of Ophthalmology at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia
Assistant in Ophthalmology, Penn Presbyterian Medical Center
Attending Staff Physician, Hospital of the Uniersity of Pennsylvania
Director, Vivian S. Lasko Ocular Vascular Laboratory, Scheie Eye Institute
Department: Ophthalmology
Contact information
SCHEIE EYE INSTITUTE
51 NORTH 39TH STREET
2689
Philadelphia, PA 19104
51 NORTH 39TH STREET
2689
Philadelphia, PA 19104
Office: 215-662-8675
Fax: 215-662-8025
Fax: 215-662-8025
Email:
juangrun@mail.med.upenn.edu
juangrun@mail.med.upenn.edu
Publications
Education:
M.D.
University of Tel-Aviv, Sackler Medical School, 1975.
M.D.
University of Tel-Aviv, Sackler Medical School, 1975.
Post-Graduate Training
Intern in Medicine, Hasharon Hospital, Petach-Tikva, Israel, 1974-1975.
Resident in Ophthalmology, Beilinson Medical Center, Petach-Tikva, Israel, 1975-1979.
Fellowship in Medical Retinal Diseases, University of Pennsylvania, Scheie Eye Institute, 1986-1987.
Intern in Medicine, Hasharon Hospital, Petach-Tikva, Israel, 1974-1975.
Resident in Ophthalmology, Beilinson Medical Center, Petach-Tikva, Israel, 1975-1979.
Fellowship in Medical Retinal Diseases, University of Pennsylvania, Scheie Eye Institute, 1986-1987.
Certifications
American Board of Ophthalmology, 1983.
Permanent linkAmerican Board of Ophthalmology, 1983.
Description of Research Expertise
Dr. Grunwald is world renowned for his research on blood flow in the retina. He has helped to develop techniques to measure the circulation in the eye. In his laboratory, the Vivian Simkins Lasko Retinal Vascular Research Laboratory, non-invasive state of the art technology is employed to study the role of circulatory changes in the development of vision-threatening eye diseases such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma, retinitis pigmentosa, and others and the pharmacologic effects of medications on the human ocular vasculature and its circulation.Clinical Trials
Dr. Grunwald is an investigator on the following trials:
•Complications of Age-Related Macular Degeneration Prevention Trial (CAPT)
•The Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
•Retinopathy in Chronic Renal Insufficiency (RCRIC)
He is the Principal Investigator of two grants that will quantitate changes occurring in the retina due to diabetic retinopathy, systemic hypertension and age-related macular degeneration.
Keywords
Age-related macular degeneration (AMD), choroidal circulation, diabetic retinopathy, ocular vasculature, optic nerve blood flow, pharmacologic effects, retina, retinal circulation, retinal vasculature
Description of Clinical Expertise
Dr. Grunwald cares for and treats patients with age-related macular degeneration, diabetic retinopathy and retinal vascular diseases at the following locations: Scheie Eye Institute, Hospital of the University of Pennsylvania, Penn Medicine at Radnor, Mercy Fitzgerald Hospital and the Veterans’ Administration Medical Center.Description of Other Expertise
Teaching. Fluency in Spanish, Hebrew and EnglishSelected Publications
Ying GS, Huang J, Maguire MG, Jaffe GJ, Grunwald JE, Toth C, Daniel E, Klein M, Pieramici D, Wells J, Martin DF; Comparison of Age-Related Macular Degeneration Treatments Trials Research Group*.: Baseline Predictors for One-Year Visual Outcomes with Ranibizumab or Bevacizumab for Neovascular Age-related Macular Degeneration. Ophthalmology. Oct 2012 Notes: pii: S0161-6420(12)00677-X. doi: 10.1016/j.ophtha.2012.07.042. [Epub ahead of print]Grunwald JE, Alexander J, Ying GS, Maguire M, Daniel E, Whittock-Martin R, Parker C, McWilliams K, Lo JC, Go A, Townsend R, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman H, Kusek JW, Xie D, Jaar BG; for the CRIC Study Group.: Retinopathy and Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort (CRIC) Study. Arch Ophthalmol. 130(9): 1136-44, Sep 2012.
Grunwald JE, Daniel E, Ying GS, Pistilli M, Maguire MG, Alexander J, Whittock-Martin R, Parker CR, Sepielli K, Blodi BA, Martin DF; CATT Research Group.: Photographic assessment of baseline fundus morphologic features in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology. 119(8): 1634-41, Aug 2012 Notes: Epub 2012 Apr 17.
Grunwald JE, Ying GS, Maguire M, Pistilli M, Daniel E, Alexander J, Whittock-Martin R, Parker C, Mohler E, Lo JC, Townsend R, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman H, Kusek JW, Xie D, Coleman M, Keane MG; Chronic Renal Insufficiency Cohort (CRIC) Study Group.: Association between retinopathy and cardiovascular disease in patients with chronic kidney disease (from the Chronic Renal Insufficiency Cohort [CRIC] Study). Am J Cardiol. 110(2): 246-53, July 2012 Notes: Epub 2012 Apr 18.
Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group, Martin DF, Maguire MG, Fine SL, Ying GS, Jaffe GJ, Grunwald JE, Toth C, Redford M, Ferris FL 3rd.: Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results. Ophthalmology 119(7): 1388-98, Jul 2012 Notes: Epub 2012 May 1.
Berenberg TL, Metelitsina TI, Madow B, Dai Y, Ying GS, Dupont JC, Grunwald L, Brucker AJ, Grunwald JE.: The association between drusen extent and foveolar choroidal blood flow in age-related macular degeneration. Retina. 32(1): 25-31, Jan 2012.
Maguire MG, Huang J, Daniel E, Martin R, Shah AR, Grunwald JE, Fine SL, Martin DF, CATT Research Group.: Incidence of Choroidal Neovascularization in the Fellow Eye Among Patients Treated with Ranibizumab or Bevacizumab in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Invest. Ophthalmol. Vis. Sci. 2012 Notes: 53: ARVO E-Abstract 3680.
Ying, G.S., Jiayan Huang, J., Maguire, M.G., Grunwald, J.E., Jaffe, G.J., Daniel F. Martin, D.F., CATT Research Group.: Baseline Predictors of Visual Acuity Response to Ranibizumab and Bevacizumab in the Comparison of AMD Treatment Trial (CATT). Invest. Ophthalmol. Vis. Sci. 2012 Notes: 53: ARVO E-Abstract 3681.
Yaffe, K., Ackerson, L., Hoang, T.D., Go, A.S., Maguire, M.G., Ying, G.S., Daniel, E., Bazzano, L.A., Coleman, M., Cohen, D.L., Glenn, M., Kusek, J.W., Ojo, A., Seliger, S., Xie, D., Grunwald, J.E.: Retinopathy and cognitive impairment among older adults with chronic kidney disease. Am J Kidney Dis. 2012 Notes: In Press.
Grunwald, JE, Daniel E, Ying GS, Pistilli M, Maguire MG, Alexander J, Fine SL, Martin, D. : Photographic Assessment Of Baseline Fundus Morphology In The Comparison Of Age-Related Macular Degeneration Treatments Trials. Invest. Ophthalmol. Vis. Sci. 2012 Notes: 53: ARVO E-Abstract 2896.
