University of Pennsylvania Health System

Department of Ophthalmology

Ophthalmology Faculty

Juan E. Grunwald, MD

faculty photo
Professor of Ophthalmology at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia
Assistant in Ophthalmology, Penn Presbyterian Medical Center
Attending Staff Physician, Hospital of the Uniersity of Pennsylvania
Director, Vivian S. Lasko Ocular Vascular Laboratory, Scheie Eye Institute
Department: Ophthalmology

Contact information
SCHEIE EYE INSTITUTE
51 NORTH 39TH STREET
2689
Philadelphia, PA 19104
Education:
M.D.
University of Tel-Aviv, Sackler Medical School, 1975.
Post-Graduate Training
Intern in Medicine, Hasharon Hospital, Petach-Tikva, Israel, 1974-1975.
Resident in Ophthalmology, Beilinson Medical Center, Petach-Tikva, Israel, 1975-1979.
Fellowship in Medical Retinal Diseases, University of Pennsylvania, Scheie Eye Institute, 1986-1987.
Certifications
American Board of Ophthalmology, 1983.
Permanent link
 
> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

Dr. Grunwald is world renowned for his research on blood flow in the retina. He has helped to develop techniques to measure the circulation in the eye. In his laboratory, the Vivian Simkins Lasko Retinal Vascular Research Laboratory, non-invasive state of the art technology is employed to study the role of circulatory changes in the development of vision-threatening eye diseases such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma, retinitis pigmentosa, and others and the pharmacologic effects of medications on the human ocular vasculature and its circulation.

Clinical Trials
Dr. Grunwald is an investigator on the following trials:
•Complications of Age-Related Macular Degeneration Prevention Trial (CAPT)
•The Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
•Retinopathy in Chronic Renal Insufficiency (RCRIC)

He is the Principal Investigator of two grants that will quantitate changes occurring in the retina due to diabetic retinopathy, systemic hypertension and age-related macular degeneration.

Keywords
Age-related macular degeneration (AMD), choroidal circulation, diabetic retinopathy, ocular vasculature, optic nerve blood flow, pharmacologic effects, retina, retinal circulation, retinal vasculature

Description of Clinical Expertise

Dr. Grunwald cares for and treats patients with age-related macular degeneration, diabetic retinopathy and retinal vascular diseases at the following locations: Scheie Eye Institute, Hospital of the University of Pennsylvania, Penn Medicine at Radnor, Mercy Fitzgerald Hospital and the Veterans’ Administration Medical Center.

Description of Other Expertise

Teaching. Fluency in Spanish, Hebrew and English

Selected Publications

Maguire Maureen G, Daniel Ebenezer, Shah Ankoor R, Grunwald Juan E, Hagstrom Stephanie A, Avery Robert L, Huang Jiayan, Martin Revell W, Roth Daniel B, Castellarin Alessandro A, Bakri Sophie J, Fine Stuart L, Martin Daniel F: Incidence of Choroidal Neovascularization in the Fellow Eye in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 120(10): 2035-2041, Oct 2013.

Jaffe Glenn J, Martin Daniel F, Toth Cynthia A, Daniel Ebenezer, Maguire Maureen G, Ying Gui-Shuang, Grunwald Juan E, Huang Jiayan: Macular Morphology and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 120(9): 1860-70, Sep 2013.

Grunwald Juan E, Daniel Ebenezer, Huang Jiayan, Ying Gui-Shuang, Maguire Maureen G, Toth Cynthia A, Jaffe Glenn J, Fine Stuart L, Blodi Barbara, Klein Michael L, Martin Alison A, Hagstrom Stephanie A, Martin Daniel F: Risk of Geographic Atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology Sep 2013 Notes: Epub ahead of print.

Hagstrom Stephanie A, Ying Gui-Shuang, Pauer Gayle J T, Sturgill-Short Gwen M, Huang Jiayan, Callanan David G, Kim Ivana K, Klein Michael L, Maguire Maureen G, Martin Daniel F: Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT). Ophthalmology 120(3): 593-9, Mar 2013.

Ying Gui-shuang, Huang Jiayan, Maguire Maureen G, Jaffe Glenn J, Grunwald Juan E, Toth Cynthia, Daniel Ebenezer, Klein Michael, Pieramici Dante, Wells John, Martin Daniel F: Baseline predictors for one-year visual outcomes with ranibizumab or bevacizumab for neovascular age-related macular degeneration. Ophthalmology 120(1): 122-9, Jan 2013.

Ying GS, Huang J, Maguire MG, Jaffe GJ, Grunwald JE, Toth C, Daniel E, Klein M, Pieramici D, Wells J, Martin DF; Comparison of Age-Related Macular Degeneration Treatments Trials Research Group*.: Baseline Predictors for One-Year Visual Outcomes with Ranibizumab or Bevacizumab for Neovascular Age-related Macular Degeneration. Ophthalmology. Oct 2012 Notes: pii: S0161-6420(12)00677-X. doi: 10.1016/j.ophtha.2012.07.042. [Epub ahead of print]

Grunwald JE, Alexander J, Ying GS, Maguire M, Daniel E, Whittock-Martin R, Parker C, McWilliams K, Lo JC, Go A, Townsend R, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman H, Kusek JW, Xie D, Jaar BG; for the CRIC Study Group.: Retinopathy and Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort (CRIC) Study. Arch Ophthalmol. 130(9): 1136-44, Sep 2012.

Grunwald JE, Daniel E, Ying GS, Pistilli M, Maguire MG, Alexander J, Whittock-Martin R, Parker CR, Sepielli K, Blodi BA, Martin DF; CATT Research Group.: Photographic assessment of baseline fundus morphologic features in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology. 119(8): 1634-41, Aug 2012 Notes: Epub 2012 Apr 17.

Grunwald JE, Ying GS, Maguire M, Pistilli M, Daniel E, Alexander J, Whittock-Martin R, Parker C, Mohler E, Lo JC, Townsend R, Gadegbeku CA, Lash JP, Fink JC, Rahman M, Feldman H, Kusek JW, Xie D, Coleman M, Keane MG; Chronic Renal Insufficiency Cohort (CRIC) Study Group.: Association between retinopathy and cardiovascular disease in patients with chronic kidney disease (from the Chronic Renal Insufficiency Cohort [CRIC] Study). Am J Cardiol. 110(2): 246-53, July 2012 Notes: Epub 2012 Apr 18.

Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group, Martin DF, Maguire MG, Fine SL, Ying GS, Jaffe GJ, Grunwald JE, Toth C, Redford M, Ferris FL 3rd.: Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results. Ophthalmology 119(7): 1388-98, Jul 2012 Notes: Epub 2012 May 1.

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Last updated: 01/24/2014
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