Venkata Ramana Murthy Chavali, Ph.D
Research Associate of Ophthalmology
Department: Ophthalmology
Contact information
422 Curie Blvd., 315 Stellar Chance Labs, University of Pennsylvania
Philadelphia, PA 19104
Philadelphia, PA 19104
Office: 4057144198
Fax: 2155736728
Lab: 2158989838
Fax: 2155736728
Lab: 2158989838
Email:
vchavali@mail.med.upenn.edu
vchavali@mail.med.upenn.edu
Publications
Links
Search PubMed for articles
Dr. Stambolian is my PI and I am currently associated with his lab.
Search PubMed for articles
Dr. Stambolian is my PI and I am currently associated with his lab.
Education:
B.Sc. (Biotechnology)
Andhra University, Visakhapatnam, INDIA, 1999.
M.Sc. (Biotechnology)
Andhra University, Visakhapatnam, INDIA, 2001.
PhD (Molecular Virology)
Indian Institute of Technology Kharagpur, INDIA, 2007.
B.Sc. (Biotechnology)
Andhra University, Visakhapatnam, INDIA, 1999.
M.Sc. (Biotechnology)
Andhra University, Visakhapatnam, INDIA, 2001.
PhD (Molecular Virology)
Indian Institute of Technology Kharagpur, INDIA, 2007.
Post-Graduate Training
Postdoctoral Fellow, Ophthalmology, University of Michigan, Ann Arbor, 2006-2007.
Postdoctoral Fellow Employee, Ophthalmology, University of California San Diego, 2008-2011.
Post doctoral Fellow, Ophthalmology, University of Pennsylvania, 2011-2012.
Permanent linkPostdoctoral Fellow, Ophthalmology, University of Michigan, Ann Arbor, 2006-2007.
Postdoctoral Fellow Employee, Ophthalmology, University of California San Diego, 2008-2011.
Post doctoral Fellow, Ophthalmology, University of Pennsylvania, 2011-2012.
Description of Research Expertise
Research in Ophthalmology; Developing animal models like mouse, zebrafish and pig models to study age-related macular degeneration, refractive error and retinal degeneration; Investigating the molecular mechanisms of gene mutations found through Gene Association studies.Selected Publications
Sommer Jeffrey R, Chavali Venkata R M, Simpson Sean G, Ayyagari Radha, Petters Robert M: Cloning, characterization, and expression analysis of the pig (Sus scrofa) C1q tumor necrosis factor-related protein-5 gene. Molecular vision 18: 92-102, 2012.Chavali Venkata Ramana Murthy, Vasireddy Vidyullatha, Ayyagari Radha: Silencing the expression of CTRP5/C1QTNF5 and ELOVL4 genes by small interfering RNA. Advances in experimental medicine and biology 723: 225-33, 2012.
Naeem Muhammad Asif, Chavali Venkata R M, Ali Shahbaz, Iqbal Muhammad, Riazuddin Saima, Khan Shaheen N, Husnain Tayyab, Sieving Paul A, Ayyagari Radha, Riazuddin Sheikh, Hejtmancik J Fielding, Riazuddin S Amer: GNAT1 Associated with Autosomal Recessive Congenital Stationary Night Blindness. Investigative ophthalmology & visual science 53(3): 1353-61, 2012.
Chavali Venkata R M, Khan Naheed W, Cukras Catherine A, Bartsch Dirk-Uwe, Jablonski Monica M, Ayyagari Radha: A CTRP5 gene S163R mutation knock-in mouse model for late-onset retinal degeneration. Human molecular genetics 20(10): 2000-14, May 2011.
Vasireddy Vidyullatha, Chavali Venkata R M, Joseph Victory T, Kadam Rajendra, Lin Jonathan H, Jamison Jeffrey A, Kompella Uday B, Reddy Geereddy Bhanuprakash, Ayyagari Radha: Rescue of photoreceptor degeneration by curcumin in transgenic rats with P23H rhodopsin mutation. PloS one 6(6): e21193, 2011.
Chavali Venkata R M, Sommer Jeffrey R, Petters Robert M, Ayyagari Radha: Identification of a promoter for the human C1Q-tumor necrosis factor-related protein-5 gene associated with late-onset retinal degeneration. Investigative ophthalmology & visual science 51(11): 5499-507, Nov 2010.
Riazuddin S Amer, Shahzadi Amber, Zeitz Christina, Ahmed Zubair M, Ayyagari Radha, Chavali Venkata R M, Ponferrada Virgilio G, Audo Isabelle, Michiels Christelle, Lancelot Marie-Elise, Nasir Idrees A, Zafar Ahmad U, Khan Shaheen N, Husnain Tayyab, Jiao Xiaodong, MacDonald Ian M, Riazuddin Sheikh, Sieving Paul A, Katsanis Nicholas, Hejtmancik J Fielding: A mutation in SLC24A1 implicated in autosomal-recessive congenital stationary night blindness. American journal of human genetics 87(4): 523-31, Oct 2010.
Li Lin, Nakaya Naoki, Chavali Venkata R M, Ma Zhiwei, Jiao Xiaodong, Sieving Paul A, Riazuddin Sheikh, Tomarev Stanislav I, Ayyagari Radha, Riazuddin S Amer, Hejtmancik J Fielding: A mutation in ZNF513, a putative regulator of photoreceptor development, causes autosomal-recessive retinitis pigmentosa. American journal of human genetics 87(3): 400-9, Sep 2010.
Ghorai Suvankar, Chakrabarti Mrinmay, Roy Sobhan, Chavali Venkata Ramana Murthy, Bagchi Abhisek, Ghosh Ananta Kumar: Molecular characterization of genome segment 2 encoding RNA dependent RNA polymerase of Antheraea mylitta cytoplasmic polyhedrosis virus. Virology 404(1): 21-31, Aug 2010.
Chang Bo, Mandal Md Nawajes A, Chavali Venkata R M, Hawes Norman L, Khan Naheed W, Hurd Ronald E, Smith Richard S, Davisson Muriel L, Kopplin Laura, Klein Barbara E K, Klein Ronald, Iyengar Sudha K, Heckenlively John R, Ayyagari Radha: Age-related retinal degeneration (arrd2) in a novel mouse model due to a nonsense mutation in the Mdm1 gene. Human molecular genetics 17(24): 3929-41, Dec 2008.
