University of Pennsylvania Health System

Department of Ophthalmology

Ophthalmology Faculty

Faculty Overview

Katayoon Baradaran Ebrahimi, MD

faculty photo
Instructor A of Ophthalmology
Department: Ophthalmology

Contact information
Scheie Eye Institute, UPenn
51 N. 39th Street, Suite 502
Philadelphia, PA 19104
Office: 215-662-8657
Fax: 215-662-9676
Lab: 215-746-0207
Education:
MD (Medicine)
Iran University of Medical Sciences and Health, 1995.
Post-Graduate Training
Ophthalmology, Iran University of Medical Sciences and Health, 1996-2000.
Ophthalmic Pathology, Moorfields Eye Hospital/UCL, 2003-2004.
Ophthalmic Pathology, Wilmer Eye Institute/Johns Hopkins University, 2005-2007.
Ocular oncology, University of California San Francisco, 2007-2008.
Molecular Pathology, University of California San Francisco, 2008-2009.
Medical Retina, Duke Eye Center/Duke University, 2016-2017.
Certifications
Ophthalmology residency/Iran University of Medical Sciences and Health, 2000.
International Council of Ophthalmology Basic Science Certificate, 2001.
International Council of Ophthalmology/ Clinical Science Certificate, 2001.
Ophthalmology Board certification/Iranian board of Ophthalmology , 2001.
Vitreoretina Observership Certificate/Moorfields Eye Hospital/University College London, 2003.
Ophthalmic pathology (ICO) Certificate/Moorfields Eye Hospital/University College London, 2004.
ECFMG Certificate, 2006.
Ocular Pathology Fellowship Certificate/Wilmer Eye Institute/Johns Hopkins University, 2007.
Ocular Oncology Fellowship Certificate/University of California San Francisco, 2008.
Molecular Pathology and Genetic Analysis/University of California San Francisco, 2009.
Vitreoretina research fellowship/Wilmer Eye Institute/Johns Hopkins University, 2013.
Medical Retina/Duke eye center/Duke University, 2017.
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Description of Clinical Expertise

My clinical research is focused on finding new biomarkers for Age Related macular Degeneration and hereditary retinal degeneration (Stargardt and Best Dystrophy), using multimodal imaging and functional analysis.

Description of Other Expertise

My translational research is focused on finding early systemic biomarkers in patients with Age-Related macular degeneration.

Description of Research Expertise

My basic research is focused on evaluating the basic mechanisms involved in the pathogenesis of Age Related Macular Degeneration. I am evaluating signaling pathways that have a role in RPE apoptosis and photoreceptor degeneration.

Selected Publications

Ebrahimi Katayoon B, Cano Marisol, Rhee John, Datta Sayantan, Wang Lei, Handa James T: Oxidative Stress Induces an Interactive Decline in Wnt and Nrf2 Signaling in Degenerating Retinal Pigment Epithelium. Antioxidants & redox signaling Jan 2018.

Light Jacob G, Fard Masoud A, Yaseri Mehdi, Aiyetan Paul, Handa James T, Ebrahimi Katayoon B: STARGARDT DISEASE: Beyond Flecks and Atrophy. Retina (Philadelphia, Pa.) 37(12): 2352-2361, Dec 2017.

Datta Sayantan, Cano Marisol, Ebrahimi Katayoon, Wang Lei, Handa James T: The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD. Progress in retinal and eye research 60: 201-218, Sep 2017.

Moghimi S, Afzali M, Akbari M, Ebrahimi K B, Khodabande A, Yazdani-Abyaneh A R, Ghafouri S N H, Coh P, Okhravi S, Fard M A: Crowded optic nerve head evaluation with optical coherence tomography in anterior ischemic optic neuropathy. Eye (London, England) 31(8): 1191-1198, Aug 2017.

Fard Masoud Aghsaei, Afzali Marjan, Abdi Parisa, Yasseri Mehdi, Ebrahimi Katayoon B, Moghimi Sasan: Comparison of the Pattern of Macular Ganglion Cell-Inner Plexiform Layer Defect Between Ischemic Optic Neuropathy and Open-Angle Glaucoma. Investigative ophthalmology & visual science 57(3): 1011-6, Mar 2016.

Wang Lei, Cano Marisol, Datta Sayantan, Wei Hong, Ebrahimi Katayoon B, Gorashi Yara, Garlanda Cecilia, Handa James T: Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation. The Journal of pathology 240(4): 495-506, 12 2016.

Wang Lei, Ebrahimi Katayoon B, Chyn Michelle, Cano Marisol, Handa James T: Biology of p62/sequestosome-1 in Age-Related Macular Degeneration (AMD). Advances in experimental medicine and biology 854: 17-22, 2016.

Handa James T, Tagami Mizuki, Ebrahimi Katayoon, Leibundgut Gregor, Janiak Anna, Witztum Joseph L, Tsimikas Sotirios: Lipoprotein(A) with An Intact Lysine Binding Site Protects the Retina From an Age-Related Macular Degeneration Phenotype in Mice (An American Ophthalmological Society Thesis). Transactions of the American Ophthalmological Society 113: T5, 2015.

Wang Lei, Kondo Naoshi, Cano Marisol, Ebrahimi Katayoon, Yoshida Takeshi, Barnett Bradley P, Biswal Shyam, Handa James T: Nrf2 signaling modulates cigarette smoke-induced complement activation in retinal pigmented epithelial cells. Free radical biology & medicine 70: 155-66, May 2014.

Cano Marisol, Wang Lei, Wan Jun, Barnett Bradley P, Ebrahimi Katayoon, Qian Jiang, Handa James T: Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells. Free radical biology & medicine 69: 1-14, Apr 2014.

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Last updated: 03/11/2018
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