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John V. Bosso, M.D., FAAAAI, FACAAI

Professor of Clinical Otorhinolaryngology: Head and Neck Surgery
Attending Physician, Clinical Professor, Hospital of the University of Pennsylvania
Director, Otorhinolaryngology: HNS Allergy Clinic, Department of Otorhinolaryngolgy: Head and Neck Surgery at the Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania
Medical Director, Penn AERD Center, Department of Otorhinolaryngology: Head and Neck Surgery at the Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania
Department: Otorhinolaryngology: Head and Neck Surgery

Contact information
Hospital of the University of Pennsylvania
Perelman Center for Advanced Medicine
South Pavilion, 3rd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-360-0372
Fax: 215-662-4613
Education:
B.S. (Biochemistry, summa cum laude)
Saint Peter's University, Jersey City, New Jersey, 1981.
M.D. (Medicine)
Jacobs School of Medicine, University at Buffalo, Buffalo, New York, 1985.
Post-Graduate Training
Internal Medicine Residency, SUNY Downstate at Staten Island University Hospital, 1985-1988.
Clinical Fellowship, Allergy/Immunology, Scripps Clinic and Research Foundation, La Jolla, California, 1988-1990.
Certifications
Diplomate, National Board of Medical Examiners , 1986.
Diplomate, American Board of Internal Medicine , 1988.
Diplomate, American Board of Allergy & Immunology, Actively participating in MOC, 1991.
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Description of Clinical Expertise

AERD/Samter's Triad
Chronic Rhinosinusitis
Nasal polyps
Aspirin/NSAID Allergy
Aspirin Desensitization
Biologicals for Asthma, CRS, Nasal Polyps
Immunotherapy for Allergic Diseases

Description of Research Expertise

AERD/Samter's Triad
Chronic Rhinosinusitis
Nasal polyps
Aspirin/NSAID Allergy
Aspirin Desensitization
Biologicals for Asthma, CRS, Nasal Polyps
Immunotherapy

Selected Publications

Herzberg SD, Bosso AM, Sangal NR, Bosso JV: Eosinophilic granulomatosis with polyangiitis presenting as aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol. M.Grayson (eds.). Science Direct, 131(4): 528-530, October 2023.

Kohanski MA, Qatanani A, Lin C, Tan LH, Chang J, Corr A, Herzberg S, Adappa ND, Palmer JN, reed DR, Bosso JV, Cohen NA. : Long-term aspirin desensitization has mucosal cytokine features of immune tolerance. Allergy Sep 20 2023 Notes: online ahead of print.

Lee DJ, Cramer HB, Kshirsagar RS, Douglas JE, Kohanski, MA, Palmer JN, Adappa ND, Bosso JV.: Dupilumab-related adverse events among patients with chronic rhinosinusitis with nasal polyposis. Int Forum Allergy Rhinol. T Smith (eds.). Wiley, 13(8): 1542-1545, August 2023.

Panara K, Grose E, Lee DJ, Safadi J, Douglas JE, Kohanski MA, Palmer JN, Lee JM, Adappa ND, Bosso JV : Readability and quality analysis of patient education materials in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol. T Smith (eds.). Wiley, June 2023 Notes: online ahead of print.

Douglas JE, Lin C, Mansfield CJ, Bell K, Salmon MK, Kohanski MA, Adappa ND, Palmer JN, Bosso JV, Reed DR, Cohen NA.: Genetics of denatonium-responsive bitter receptors in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol. Timothy Smith, MD (eds.). Wiley, 13(3): 269-272, March 2023.

Tripathi SH, Corr A, Kumar A, Ungerer H, Salmon M, Adappa ND, Bosso JV: SNOT-22 scores after 6 months of aspirin therapy are predictive of long-term quality of life in AERD. Allergy Asthma Proc. J.Bellanti and R. Settipane (eds.). 44(1): 78-80, Jan 2023.

Douglas JE, Bosso JV: What's New in AERD? Am J Allergy Rhinol. R Sindwani, MD (eds.). Sage, 2023.

Sell EA, Tan LH, Lin C, Bosso JV, Palmer JN, Adappa ND, Lee RJ, Kohanski MA, Reed DR, Cohen NA. : Microbial metabolite succinate activates solitary chemosensory cells in the human sinonasal epithelium. Int Forum Allergy Rhinol. Timothy Smith, MD (eds.). Wiley, Page: Online ahead of print, Dec 2022.

Lee DJ, Cramer HB, Kshirsagar RS, Douglas JE, Kohanski MA, Palmer JN, Adappa ND, Bosso JV.: Dupilumab-related adverse events among patients with chronic rhinosinusitis with nasal polyposis. . Int Forum Allergy Rhinol. Timothy Smith, MD (eds.). Wiley, Nov 2022 Notes: 2022.

Tan LH, Lin C, Ungerer H, Kumar A, Qatanani A, Adappa ND, Palmer JN, Bosso JV, Reed D, Cohen NA, Kohanski MA: Steroid affected cytokines in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol. Timothy Smith, MD (eds.). Wiley, 12(10): 1232-1241, October 2022.

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Last updated: 10/30/2023
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