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Daniel H. Wolf

Associate Professor of Psychiatry
Attending Psychiatrist, Hospital of the University of Pennsylvania, Philadelphia
Faculty Member, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia
Staff Psychiatrist, Pennsylvania Hospital, Philadelphia
Faculty Member, Center for Functional Neuroimaging (CfN), Perelman School of Medicine at the University of Pennsylvania, Philadelphia
Staff Psychiatrist, Penn Presbyterian Medical Center, Philadelphia
Faculty Member, Center for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine at the University of Pennsylvania, Philadelphia
Faculty Member, T32 Integrative Training in the Neurocircuitry of Affective Disorders, University of Pennsylvania, Perelman School of Medicine
Faculty Member, T32 Training Program in Neuropsychopharmacology, University of Pennsylvania
Associate Director, Psychosis T32 Fellowship Program, Perelman School of Medicine at the University of Pennsylvania, Philadelphia
Director, Clinical Neuroscience Training Program, Perelman School of Medicine at the University of Pennsylvania, Philadelphia
Faculty Member, T32 Neuroscience Training Grant (Jointly Sponsored Institutional Predoctoral Training Program in the Neurosciences, JSPTPN), University of Pennsylvania
Department: Psychiatry
Graduate Group Affiliations

Contact information
Richards Building, Room A506
University of Pennsylvania
3700 Hamilton Walk
Philadelphia, PA 19104
Office: 215-662-3692
Fax: 215-662-7903
Education:
A.B. (Biology)
Harvard College, 1992.
Ph.D. (Neuroscience)
Yale University School of Medicine, 2000.
M.D. (Medicine)
Yale University School of Medicine, 2001.
Post-Graduate Training
Intern in Transitional Medicine, Albert Einstein Medical Center, Philadelphia, 2001-2002.
Resident in Psychiatry, McLean Hospital and Massachusetts General Hospital, Boston, MA, 2002-2005.
Chief Resident, Schizophrenia and Bipolar Disorders Program, McLean & Massachusetts General Hospitals, Boston, MA, 2004-2005.
Postdoctoral Fellow in Neuropsychiatry, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, 2005-2008.
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Description of Research Expertise

Key Words
psychosis, reward, motivation, negative symptoms, fMRI, pharmacological imaging

Research interests, techniques, and summary:
My overarching goal is to develop a translational research program to study the neural mechanisms of reward and motivation deficits in psychosis, depression, addiction, and other psychiatric disorders, and in those at risk for these disorders. By utilizing pharmacological challenges during functional neuroimaging, together with detailed clinical and behavioral assessments, I seek to relate these deficits to dysfunction in specific neural circuits, and develop better methods for assessing novel therapeutic interventions. I am also developing active collaborations with geneticists, animal researchers, and pharmaceutical industry scientists in order facilitate clinical translation of basic neuroscientific discoveries.

Description of Clinical Expertise

Dr. Wolf is a board-certified psychiatrist, with particular expertise in the treatment of adults with psychotic disorders.
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Last updated: 09/01/2023
The Trustees of the University of Pennsylvania
 
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