faculty photo

Steven J. Siegel

Associate Professor of Psychiatry
Department: Psychiatry
Graduate Group Affiliations

Contact information
Rm 2202
125 S. 31st street
Translational Research Building
Philadelphia, PA 19104-4283
Office: 215 573 0278
Education:
B.A. (Neuroscience)
Colgate University, 1986.
Ph.D. (Neurobiology)
Mount Sinai School of Medicine, 1994.
M.D.
Medicine Mount Sinai School of Medicine, 1996.
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Selected Publications

Amann, L. C., Halene, T. B., Ehrlichman, R. S., Luminais, S. N., Ma, N., Abel, T., Siegel, S. J.: Chronic ketamine impairs fear conditioning and produces long-lasting reductions in auditory evoked potentials. 35(2): 311-7, 2009.

Bodarky, C. L., Halene, T. B., Ehrlichman, R. S., Banerjee, A., Ray, R., Hahn, C. G., Jonak, G., Siegel, S. J.: Novel Environment and GABA Agonists Alter ERPs in NMDA NR1 Hypomorphic and Wild-type Mice. J Pharmacol Exp Ther 2009.

Halene, T. B., Ehrlichman, R. S., Liang, Y., Christian, E. P., Jonak, G. J., Gur, T. L., Blendy, J. A., Dow, H. C., Brodkin, E. S., Schneider, F., Gur, R. C., Siegel, S. J.: Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia. Genes Brain Behav 2009.

Ehrlichman, R. S., Luminais, S. N., White, S. L., Rudnick, N. D., Ma, N., Dow, H. C., Kreibich, A. S., Abel, T., Brodkin, E. S., Hahn, C. G., Siegel, S. J.: Neuregulin 1 transgenic mice display reduced mismatch negativity, contextual fear conditioning and social interactions. Brain Res 2009.

Ehrlichman, R. S., Gandal, M. J., Maxwell, C. R., Lazarewicz, M. T., Finkel, L. H., Contreras, D., Turetsky, B. I., Siegel, S. J.: N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia. Neuroscience 158(2): 705-12, 2009.

Lazarewicz, M. T., Ehrlichman, R. S., Maxwell, C. R., Gandal, M. J., Finkel, L. H., Siegel, S. J.: Ketamine Modulates Theta and Gamma Oscillations. J Cogn Neurosci 2009.

Siegel, S. J., Irani, F., Brensinger, C. M., Kohler, C. G., Bilker, W. B., Ragland, J. D., Kanes, S. J., Gur, R. C., Gur, R. E.: Prognostic variables at intake and long-term level of function in schizophrenia. Am J Psychiatry 163(3): 433-41, 2006.

Halene, T. B., Siegel, S. J.: Antipsychotic-like properties of phosphodiesterase 4 inhibitors: evaluation of 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone (RO-20-1724) with auditory event-related potentials and prepulse inhibition of startle. J Pharmacol Exp Ther 326(1): 230-9, 2008.

Majewski-Tiedeken, C. R., Rabin, C. R., Siegel, S. J.: Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains. 92(1-3): 217-27, 2008.

Ehrlichman, R. S., Maxwell, C. R., Majumdar, S., Siegel, S. J.: Deviance-elicited Changes in Event-related Potentials are Attenuated by Ketamine in Mice. J Cogn Neurosci 20(8): 1403-14, 2008.

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Last updated: 11/12/2009
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