Faculty & Staff

R. Nick Bryan, M.D., Ph.D

faculty photo
Emeritus Professor of Radiology
Department: Radiology

Contact information
104 Surgeon General Court
Philadelphia, PA 19146
Office: 215-662-3660
Fax: 215-615-3681
Education:
Pre-Med
Johns Hopkins University, 1965.
M.D. (Medicine)
University of Texas Medical Branch, Galveston, Texas, 1969.
Intership (Radiology)
University of Texas Medical Branch, Galveston Texas, 1970.
Post Doc (Neuroscience)
University of Texas Medical Branch, Galveston Texas, 1971.
Ph.D. (Anatomy)
University of Texas Medical Branch, Galveston, TX, 1973.
Fellow (NIH Neuroradiology)
Columbia Presbyterian Hospital, 1974.
Post-Graduate Training
Internship: Rotating/Radiology, University of Texas Medical Branch, Galveston, Texas, 1969-1970.
Fellowship in Neuroanatomy: NIH Postdoctoral with Dr. W.D. Willis, Marine Biomedical Institute, 1970-1971.
Radiology Residency, University of Texas Medical Branch, Galveston, Texas, 1971-1973.
NIH Special Fellow (Neuroradiology), Neurological Institute of New York, NYC , 1973-1974.
Certifications
Diagnostic Radiology (Neuroradiology, 1995), 1974.
American Board of Radiology Certification of Added Qualifications (CAQ) - Neuroradiology, 1995.
American Board of Radiology (MOC) - Neuroradiology, 2004.
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Description of Research Expertise

Cerebral MRI findings and cognitive functioning; applications of perfusion MRI for neurological studies; development of spatially-oriented databases for digital brain images; nuclear magnetic resonance evaluation of stroke; physiologic imaging of human brain tumors.

Description of Clinical Expertise

Neuroradiology

Selected Publications

Launer LJ, Lewis CE, Schreiner PJ, Sidney S, Battapady H, Jacobs DR, Lim KO, D'Esposito M, Zhang Q, Reis J, Davatzikos C, BryanRN. : Vascular factors and multiple measures of early brain health: CARDIA Brain MRI Study PLOS ONE 3(10), March 2015.

Benjamin F.J. Verhaaren*, MD, PhD; Stéphanie Debette*, MD, PhD; Joshua C. Bis*, PhD; Jennifer A. Smith*, PhD, MPH, MA; M. Kamran Ikram MD, PhD; Hieab H. Adams, MSc; Ashley H. Beecham, MSc; van Buchem, MD, PhD; Jeroen van der Grond, PhD; Albert V. Smith, PhD; Katrin Hegenscheid, MD; Neelum T. Aggarwal, MD; Mariza de Andrade, PhD; Elizabeth J. Atkinson, PhD; Marian Beekman, PhD; Alexa S. Beiser, PhD; Susan H. Blanton, PhD; Eric Boerwinkle, PhD; Adam M. Brickman PhD; R. Nick Bryan MD, PhD; Ganesh Chauhan, PhD; Christopher P.L.H. Chen, FRCP; Vincent Chouraki MD, PhD; Anton J.M. de Craen, PhD; Fabrice Crivello, PhD; Mary Cushman MD, MSc; Ian J. Deary, PhD; Joris Deelen, MSc; Philip L. deJager MD, PhD; Carole Dufouil, PhD; Mitchell S.V. Elkind, MD, MSc;33 Denis A. Evans MD;13 Paul Freudenberger, MSc;34 Rebecca F. Gottesman, MD, PhD;35 Vilmundur Guðnason, MD, PhD; Mohamad Habes, PhD; Susan R. Heckbert MD, PhD; Gerardo Heiss, MD; Saima Hilal, MBBS; Edith Hofer, PhD; Albert Hofman, MD, PhD; Carla A. Ibrahim-Verbaas, MD; Wouter J. Jukema, MD, PhD; David S. Knopman, MD; Cora E. Lewis MD, MSPH; Jiemin Liao, MSc; David C.M. Liewald, BSc; Michelle Luciano, PhD; Aad van der Lugt, MD, PhD; Oliver O. Martinez, PhD; Richard Mayeux MD, MSc; Bernard Mazoyer, MD, PhD; Mike Nalls, PhD; Matthias Nauck, MD; Wiro J. Niessen, PhD; Ben A. Oostra, PhD; Bruce M. Psaty, MD, PhD; Kenneth M. Rice, PhD; Jerome I. Rotter, MD; Bettina von Sarnowski, MD; Helena Schmidt, MD, PhD; Pamela J. Schreiner, PhD; Maaike Schuur, MD, PhD; Stephen S. Sidney, MD, MPH; Sigurdur Sigurdsson, MSc; P. Eline Slagboom, PhD; David J.M. Stott, MD; John C. van Swieten, MD, PhD; Alexander Teumer, PhD; Anna Maria Töglhofer, MSc; Matthew Traylor, MSc; S. Trompet, PhD; Stephen T. Turner, MD; Christophe Tzourio, MD, PhD; Hae-Won Uh, PhD; André G. Uitterlinden, PhD; Meike W. Vernooij, MD, PhD; Jing J. Wang, PhD; Tien Y. Wong, MD, PhD; Joanna M. Wardlaw, MD; B. Gwen Windham, MD; Katharina Wittfeld; Christiane Wolf, PhD; Clinton B. Wright, MD; Qiong Yang, PhD; Wei Zhao, MD, PhD; Alex Zijdenbos, PhD; Ralph L. Sacco, MD; Sharon L.R. Kardia, PhD; Philippe Amouyel, MD, PhD; Thomas H. Mosley, PhD; W. T. Longstreth, Jr, MD, MPH; Charles C. DeCarli, MD; Cornelia M. van Duijn, PhD; Reinhold Schmidt, MD; Lenore J. Launer, PhD; Hans J. Grabe*, MD; Sudha S. Seshadri, MD; M. Arfan Ikram*, MD, PhD; Myriam Fornage*, PhD;: Multiethnic genomewide association study of cerebral white matter lesions on MRI. Annals of Neurology February 2015.

Benjamin Verhaaren, Stéphanie Debette, Joshua Bis, Jennifer Smith, Mohammad Kamran Ikram, Hieab Adams, Ashley Beecham, Kumar Rajan, Lorna Lopez, Sandra Barral, Mark van Buchem, Jeroen van der Grond, Albert Smith, Katrin Hegenscheid, Neelum Aggarwal, Mariza de Andrade, Elizabeth Atkinson, Marian Beekman, Alexa Beiser, Susan Blanton, Eric Boerwinkle, Adam Brickman, Nick Bryan, Ganesh Chauhan, Christopher Chen, Vincent Chouraki, Anton JM de Crean, Fabrice Crivello, Ian Deary, Joris Deelen, Philip De Jager, Carole Dufouil, Mitchell Elkind, Denis Evans, Paul Freudenberger, Rebecca Gottesman, Vilmundur Gudnason, Mohamad Habes, Susan Heckbert, Gerardo Heiss, Saima Hilal, Edith Hofer, Albert Hofman, Carla Ibrahim-Verbaas, David Knopman, Cora Lewis, Jiemin Liao, David Liewald, Michelle Luciano, Aad van der Lugt, Oliver Martinez, Richard Mayeux, Bernard Mazoyer, Michael Nalls, Matthias Nauck, Wiro Niessen, Ben Oostra, Bruce Psaty, Ken Rice, Jerome Rotter, Bettina von Sarnowski, Helena Schmidt, Pamela Schreiner, Maaike Schuur, Stephen Sidney, Sigurdur Sigurdsson, P. Slagboom, David Stott, John van Swieten, Alexander Teumer, Anna Töglhofer, Matthew Traylor, Stella Trompet, Stephen Turner, Christophe Tzourio, Hae-Won Uh, Andre Uitterlinden, Meike Vernooij, Jing Wang, Tien Y. Wong, Joanna Wardlaw, Beverly Gwen Windham, Katharina Wittfeld, Christiane Wolf, Clinton Wright, Qiong Yang, Wei Zhao, Alex Zijdenbos, J. Wouter Jukema, Ralph Sacco, Sharon Kardia, Philippe Amouyel, Thomas Mosley, W.T. Longstreth, Jr., Charles DeCarli, Cornelia van Duijn, Reinhold Schmidt, Lenore Launer, Hans Grabe, Sudha Seshadri, M. Arfan Ikram, and Myriam Fornage : Multi-ethnic genome-wide association study of cerebral white matter hyperintensities on MRI Cardiovascular Genetics February 2015.

Erus G, Battapady H. Zhang T, Lovato J, Miller ME, Williamson JD, Launer LJ, Bryan RN, Davatziko C.: Spatial patterns of structural brain changes in type 2 diabetic patients and their longitudinal progression with intensive control of blood vessels. Diabetes Care 38(1): 97-104, January 2015.

Martine Elbejjani, PhD, Pamela Schreiner, PhD, R. Nick Bryan, MD PhD, David Siscovick MD, Lenore J. Launer, PhD: Testosterone and Sex-Hormone Binding Globulin Levels and Brain Regions Associated with Cognitive Disorders in Middle-Age Men. Epidemiology 2015.

Hugenschmidt Christina E, Lovato James F, Ambrosius Walter T, Bryan R Nick, Gerstein Hertzel C, Horowitz Karen R, Launer Lenore J, Lazar Ronald M, Murray Anne M, Chew Emily Y, Danis Ronald P, Williamson Jeff D, Miller Michael E, Ding Jingzhong: The Cross-Sectional and Longitudinal Associations of Diabetic Retinopathy With Cognitive Function and Brain MRI Findings: The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial. Diabetes care 37(12): 3244-52, December 2014.

Zi Zhang, MD, MSCE; James Lovato, MS; Harsha Battapady, MS BME; Christos Davatzikos, PhD; Hertzel C. Gerstein, MD, MSc; Faramarz Ismail-Beigi, MD, PhD; Lenore J. Launer, PhD; Anne Murray, MD, MS; Zubin Punthakee, MD; Amilcar A. Tirado, MD; Jeff Williamson, MD; R. Nick Bryan, MD, PhD; Michael E. Miller, PhD. : Effect of Hypoglycemia on Brain Structure in People with Type 2 Diabetes: Epidemiological Analysis of the ACCORD-MIND MRI Trial. Diabetes Care 37(12), December 2014.

Bryan RN, Jacobs DR, Zhu N, Schreiner PJ, Launer L, Whitmer R, Sidney S, Demerath E, Thomas W, Bouchard C, He K, Guray E, Harsha B.: Cardiorespiratory fitness in relation to brain volume and white matter integrity and blood flow: The CARDIA Study. Neurology 2: 123, September 2014.

Barzilay J, Morgan T, Murray A, Bryan RN, William J, Schnall A, Launer L.: Brain MRI Findings in Diabetic Adults with Albuminuria The ACCORD MIND Study. Clinical Journal of the American Society of Nephrology September 2014.

Bryan RN, Bilello M, Davatzikos C, Lazar RM, Murray A, Horowitz K, Lovato J, Miller ME, Williamson J, Launer LJ.: Effect of diabetes on brain structure: the action to control cardiovascular risk in diabetes MR imaging baseline data. Radiology 272(1): 210-6, July 2014.

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Last updated: 05/04/2015
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