Faculty & Staff

R. Nick Bryan, M.D., Ph.D

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Emeritus Professor of Radiology
Department: Radiology

Contact information
Department of Radiology
Perelman School of Medicine
University of Pennsylvania Health System
3600 Market Street, Suite 370
Philadelphia, PA 19104-4283
Office: 215-662-3660
Fax: 215-615-3681
M.D. (Medicine)
University of Texas Medical Branch, Galveston, Texas, 1969.
Ph.D. (Anatomy)
University of Texas Medical Branch, Galveston, TX, 1973.
Post-Graduate Training
Internship: Rotating/Radiology, University of Texas Medical Branch, Galveston, Texas, 1969-1970.
Fellowship in Neuroanatomy: NIH Postdoctoral with Dr. W.D. Willis, Marine Biomedical Institute, 1970-1971.
Radiology Residency, University of Texas Medical Branch, Galveston, Texas, 1971-1973.
NIH Special Fellow (Neuroradiology), Neurological Institute of New York, NYC , 1973-1974.
Diagnostic Radiology (Neuroradiology, 1995), 1974.
American Board of Radiology Certification of Added Qualifications (CAQ) - Neuroradiology, 1995.
American Board of Radiology (MOC) - Neuroradiology, 2004.
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Description of Research Expertise

Cerebral MRI findings and cognitive functioning; applications of perfusion MRI for neurological studies; development of spatially-oriented databases for digital brain images; nuclear magnetic resonance evaluation of stroke; physiologic imaging of human brain tumors.

Description of Clinical Expertise


Selected Publications

Laura H Coker, Mark A Espeland, Patricia E Hogan, Susan M Resnick, R Nick Bryan, Jennifer G Robinson, Joseph S Goveas, Christos Davatzikos, Lewis H Kuller, Jeff D Williamson, Cheryl D Bushnell, and Sally A Shumaker : Change in Brain and Lesion Volumes Following CEE Therapies: The WHIMS MRI Studies NEUROLOGY 82(5): 427-34, February 2014.

Rapp SR, Espeland ME, Manson JE, Resnick SM, Bryan NR, Smoller S, Coker LH, Phillips LS, Stefanick ML, and Sarto GE for the Women’s Health Initiative Memory Study.: Educational attainment, MRI changes and cognitive function in older postmenopausal women from the Women’s Health Initiative Memory Study. International J Psychiatry in Medicine 46(2): 119-141, 2014.

Mark D. Sullivan, MD, PhD;Wayne J. Katon, MD; Laura C. Lovato, MA; Michael E. Miller, PhD; Anne M. Murray, MD; Karen R. Horowitz, MD; R. Nick Bryan, MD; Hertzel C. Gerstein, MD; Santica Marcovina, MD; Basil E. Akpunonu, MD; Janice Johnson, BA; Jean Francois Yale, MD; Jeff Williamson, MD; Lenore J. Launer, PhD: Association of Depression With Accelerated Cognitive Decline Among Patients With Type 2 Diabetes in the ACCORD-MIND Trial. JAMA Psychiatry 70(10): 1041-1047, October 2013.

Halstead, M and Bryan, R.N.: Young to Middle Age 25 Year Pulse Pressure Trajectories and the Brain: The Coronary Artery Risk Development in Young Adults (CARDIA) Brain Study. 6th International Society of Vascular Behavioural and Cognitive Disorders (VAS COG) June 2013.

Tanwar, M, Herskovits, E H, Nasrallah, I M, Kundel, H, Mohan, S, Li, C, Lynch, M C, Bryan, R N : Evaluation of a Bayesian Expert System for Aiding Neuroradiology Diagnoses: A Pilot Study. American Society of Neuroradiology Annual Meeting. May 2013.

A statement about authorship from individual members of the International Society for Strategic Studies in Radiology (IS3R). European radiology 23(1): 1-2, Jan 2013.

Espeland Mark A, Bryan R Nick, Goveas Joseph S, Robinson Jennifer G, Siddiqui Mustafa S, Liu Simin, Hogan Patricia E, Casanova Ramon, Coker Laura H, Yaffe Kristine, Masaki Kamal, Rossom Rebecca, Resnick Susan M: Influence of type 2 diabetes on brain volumes and changes in brain volumes: results from the Women's Health Initiative Magnetic Resonance Imaging studies. Diabetes care 36(1): 90-7, Jan 2013.

Na Zhu, David R Jacobs, Pamela J Schreiner, Kristine Yaffe, R Nick Bryan, Lenore J Launer, Rachel A Whitmer, Stephen Sidney, Ellen Demerath, William Thomas, Claude Bouchard, Ka He, Jared Reis, and Barbara Sternfeld: Cardiorespiratory Fitness and Cognitive function in Middle-Age: The CARDIA Study. NEUROLOGY 539072, 2013.

Hendee W, Bosma JL, Bresolin LB, Berlin L, Bryan RN, Gunderman RB : Web modules on professionalism and ethics. J Am Coll Radiol 9(3): 170-3, Mar 2012

Bryan RN: Science to Practice: Is T2* Enough to Assess Oxygenation? Radiology 262(2): 375-7, Feb 2012

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Last updated: 09/16/2014
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