Faculty & Staff
Ari Borthakur, PhD
Assistant Professor of Radiology
Department: Radiology
Contact information
MMRRCC,
B1 Stellar-Chance Labs
422 Curie Blvd.
Philadelphia, PA 19104
B1 Stellar-Chance Labs
422 Curie Blvd.
Philadelphia, PA 19104
Office: (215) 573-8482
Fax: (215) 573-2113
Fax: (215) 573-2113
Email:
ari@mail.mmrrcc.upenn.edu
ari@mail.mmrrcc.upenn.edu
Graduate Group Affiliations
Publications
Education:
BS (Physics)
Angelo State University, San Angelo, TX, 1994.
PhD (Biophysics)
University of Pennsylvania, Philadelphia, PA, 2000.
Permanent linkBS (Physics)
Angelo State University, San Angelo, TX, 1994.
PhD (Biophysics)
University of Pennsylvania, Philadelphia, PA, 2000.
Description of Research Expertise
The goal of our research is to develop non-invasive and non-destructive techniques for the study of Alzheimer’s Disease and arthritis. We facilitate timely clinical diagnoses by inventing and improving MRI pulse sequences and hardware. Our multi-nuclear and relaxometric techniques are routinely applied in model systems as well as in clinical research. We maintain active partnerships with faculty from Pathology, Neurology, Orthopedic Surgery and Rheumatology departments and recruit doctoral candidates from Biophysics and Bioengineering graduate programs.Selected Publications
Wheaton AJ., Dodge GR., Borthakur A., Kneeland JB., Schumacher HR., Reddy R.: Detection of changes in articular cartilage proteoglycan by T(1rho) magnetic resonance imaging. Journal of Orthopaedic Research 23(1): 102-8, Jan 2005.Gougoutas AJ., Wheaton AJ., Borthakur A., Shapiro EM., Kneeland JB., Udupa JK., Reddy R.: Cartilage volume quantification via Live Wire segmentation. Academic Radiology 11(12): 1389-95, Dec 2004.
Wheaton AJ., Borthakur A., Corbo MT., Moonis G., Melhem E., Reddy R.: T2rho-weighted contrast in MR images of the human brain. Magnetic Resonance in Medicine 52(6): 1223-7, Dec 2004.
Wheaton AJ., Borthakur A., Kneeland JB., Regatte RR., Akella SV., Reddy R.: In vivo quantification of T1rho using a multislice spin-lock pulse sequence. Magnetic Resonance in Medicine 52(6): 1453-8, Dec 2004.
Akella SV., Regatte RR., Wheaton AJ., Borthakur A., Reddy R.: Reduction of residual dipolar interaction in cartilage by spin-lock technique. Magnetic Resonance in Medicine 52(5): 1103-9, Nov 2004.
Wheaton AJ., Casey FL., Gougoutas AJ., Dodge GR., Borthakur A., Lonner JH., Schumacher HR., Reddy R.: Correlation of T1rho with fixed charge density in cartilage. Journal of Magnetic Resonance Imaging 20(3): 519-25, Sep 2004.
Wheaton AJ., Borthakur A., Dodge GR., Kneeland JB., Schumacher HR., Reddy R.: Sodium magnetic resonance imaging of proteoglycan depletion in an in vivo model of osteoarthritis. Academic Radiology 11(1): 21-8, Jan 2004.
Regatte RR., Akella SV., Wheaton AJ., Lech G., Borthakur A., Kneeland JB., Reddy R.: 3D-T1rho-relaxation mapping of articular cartilage: in vivo assessment of early degenerative changes in symptomatic osteoarthritic subjects. Academic Radiology 11(7): 741-9, Jul 2004.
Wheaton AJ., Borthakur A., Corbo M., Charagundla SR., Reddy R.: Method for reduced SAR T1rho-weighted MRI. Magnetic Resonance in Medicine 51(6): 1096-102, Jun 2004.
Wheaton AJ., Borthakur A., Shapiro EM., Regatte RR., Akella SV., Kneeland JB., Reddy R.: Proteoglycan loss in human knee cartilage: quantitation with sodium MR imaging--feasibility study. Radiology 231(3): 900-5, Jun 2004.
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