Faculty & Staff

Ann-Marie Chacko

faculty photo
Research Associate of Radiology
Department: Radiology

Contact information
Clinical Molecular Imaging & Nuclear Medicine
Department of Radiology
Perelman School of Medicine
University of Pennsylvania
Room 288, Chemistry Building 1958 Wing
231 S. 34 Street
Philadelphia, PA 19104
Lab: 215-746-8754
Education:
B.Sc. (Biochemistry Honors)
Bishop's University, 2001.
M.Sc. (Chemistry)
University of Western Ontario, 2003.
Ph.D. (Pharmacology)
University of Pennsylvania, 2008.
M.T.R. (Translational Research)
University of Pennsylvania, 2015.
Post-Graduate Training
Postdoctoral Researcher, Pharmacology, and Institutes for Translational Medicine and Therapeutics, and Environmental Medicine, University of Pennsylvania, Philadelphia, PA , 2008-2011.
Postdoctoral Researcher, Nuclear Medicine & Clinical Molecular Imaging, University of Pennsylvania, Philadelphia, PA, 2011-2012.
CTSA KL2 Scholar, ITMAT, University of Pennsylvania, Philadelphia, PA, 2012-2014.
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Selected Publications

Simone Eric A, Zern Blaine J, Chacko Ann-Marie, Mikitsh John L, Blankemeyer Eric R, Muro Silvia, Stan Radu V, Muzykantov Vladimir R: Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124. Biomaterials 33(21): 5406-13, Jul 2012.

Ann-Marie Chacko, Catherine Hou, John Mikitsh, John Babich, and Daniel Pryma: Characterization of Ultratrace MIBG in mouse model of pheochromocytoma: Toward 211At-MABG therapy J. Nucl. Med. Meeting Abstracts 53(S1): 110, May 2012.

Batra, V., Chacko, A.-M., Hou, C., Belcastro, L., Winter, C., Gustafson, W. C., Weiss, W., Pryma, D. and Maris, J.: Uptake of the targeted radiotherapeutic iodinated benzylguanidine is directly related to norepinephrine receptor density on neuroblastoma cells. 2012 ASPHO Abstracts. Pediatric Blood & Cancer. 58(7): 1014-97, 2012.

Chacko Ann-Marie, Nayak Madhura, Greineder Colin F, Delisser Horace M, Muzykantov Vladimir R: Collaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targeting. PloS One 7(4): e34958, 2012.

Chacko Ann-Marie, Divgi Chaitanya R: Radiopharmaceutical chemistry with iodine-124: a non-standard radiohalogen for positron emission tomography. Medicinal Chemistry 7(5): 395-412, Sep 2011.

Chacko Ann-Marie, Hood Elizabeth D, Zern Blaine J, Muzykantov Vladimir R: Targeted Nanocarriers for Imaging and Therapy of Vascular Inflammation. Current Opinion in Colloid & Interface Science 16(3): 215-227, Jun 2011.

Chacko, A.-M., Li, C., Muzykantov, V.R., Coukos, G. and Divgi, C. R. : 124I-PET imaging of the ovarian cancer vascular marker TEM1. J. Nucl. Med. Meeting Abstracts 51(S2): 1110, May 2010.

Li, C., Hasegawa, K., Chacko, A.-M., Muzykantov, V. R., Divgi, C., Gimotty, P. A., Grasso, L. and Coukos, G.: In vivo modeling and detection of ovarian cancer vascular marker TEM1. J. Immunother. 33(8): 901, 2010.

Chacko Ann-Marie, Blankemeyer Eric, Lieberman Brian P, Qu Wenchao, Kung Hank F: 5-[18F]Fluoroalkyl pyrimidine nucleosides: probes for positron emission tomography imaging of herpes simplex virus type 1 thymidine kinase gene expression. Nuclear Medicine and Biology 36(1): 29-38, Jan 2009.

Chacko Ann-Marie, Qu Wenchao, Kung Hank F: Synthesis and in vitro evaluation of 5-[18F]fluoroalkyl pyrimidine nucleosides for molecular imaging of herpes simplex virus type 1 thymidine kinase reporter gene expression. Journal of Medicinal Chemistry 51(18): 5690-701, Sep 2008.

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Last updated: 06/18/2012
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