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Walter R. Witschey, PhD

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Assistant Professor of Radiology
Department: Radiology

Contact information
Smilow Center for Translational Research
University of Pennsylvania
3400 Civic Center Blvd.
Bldg.421, 7th floor, Room 103
Philadelphia, PA 19104
Office: 215-662-2310
Lab: 215-746-4048
Graduate Group Affiliations
B.S. (Physics)
University of Virginia, 2004.
Ph.D (Biochemistry and Molecular Biophysics)
University of Pennsylvania, 2009.
Post-Graduate Training
Postdoctoral/Medical Imaging, University of Pennsylvania, 2009-2010.
Postdoctoral Fellowship, Cardiovascular Imaging, University of Pennsylvania, 2011-2013.
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Description of Research Expertise

The main focus of my research is to develop effective ways to non-invasively characterize the relationships between brain, heart and arteries in cardiovascular disease and the progression to heart failure. To elucidate the pathogenesis of heart failure, my research group develops magnetic resonance imaging (MRI) approaches that establish relationships between the different organs implicated in heart disease. Our major areas of interest are the determinants of cardiac contractile function, arrhythmias, and autonomic nervous system control of the heart.

We use a multidisciplinary approach, integrating techniques from RF and electromagnetic engineering, computer vision, applied mathematics (inversion and optimization problems) and nuclear spin physics with a special emphasis on the real-time and nonlinear dynamics of the cardiovascular system.

Selected Publications

Witschey WR, Contjoch F, McGarvey JR, Ferrari VA, Hansen MS, Lee ME, Takebayashi S, Aoki C, Chirinos JA, Yushkevich PA, Gorman JH 3rd, Pilla JJ, Gorman RC.: Real-time magnetic resonance imaging technique for determining left ventricle pressure-volume loops. Ann Thorac Surg 97(5): 1597-603, May 2014.

Han Y, Liimatainen T, Gorman R, Witschey WRT: Assessing myocardial disease using T1rho MRI. Current Cardiovascular Imaging Reports 7(2): 65-81, Feb 2014.

Contijoch F, Han Y, Hansen MS, Pilla JJ, Gorman JH, Gorman RC, Witschey WRT. : Non-Cartesian retrospective reconstruction of cardiac motion in patients with severe arrhythmia. Proc Intl Soc Magn Reson Med May 10-16 2014 Notes: Oral presentation.

Haris M, Singh A, Cai K, Kogan F, McGarvey J, DeBrosse C, Zsido GA, Witschey WRT, Koomalsingh K, Pilla JJ, Chirinos JA, Ferrari VA, Gorman JH, Hariharan H, Gorman RC, Reddy R. : A novel technique for in vivo mapping of myocardial creatine kinase metabolism. Nat Med. 20(2): 209-214, Feb 2014.

Welz AM, Testud F, Cocosco CA, Dewdney A, Lehr H, Gallichan D, Jia F, Post H, Schmitt H, Schultz G, Weber H, Witschey WRT, Korvink J, Hennig J, Zaitsev M.: Development and characterization of an unshielded PatLoc gradient coil for human head imaging. Magn Reson Med. 43(4): 111-25, Oct 2013.

Witschey WRT, Littin S, Cocosco CA, Gallichan D, Schultz G, Weber H, Welz A, Hennig J, Zaitsev M.: Stages: Sub-Fourier Dynamic Shim Updating Using Nonlinear Magnetic Field Phase Preparation. Magn Reson Med 71(1): 57-66, Jan 2014.

Schultz G, Gallichan D, Weber H, Witschey WR, Honal M, Hennig J, Zaitsev M.: Image reconstruction in k-space from MR data encoded with ambiguous gradient fields. Magn Reson Med 73(2): 857-64, Feb 2015.

Witschey WR, Zsido GA, Koomalsingh K, Kondo N, Minakawa M, Shuto T, McGarvey JR, Levack MA, Contijoch F, Pilla JJ, Gorman JH, Gorman RC: In vivo chronic myocardial infarction characterization by spin locked cardiovascular magnetic resonance. J Cardiovascular Magnetic Resonance Page: 37, June 2012.

McGarvey JR, Kondo N, Takebe M. Koomalsingh KJ, Witschey WR, Barker AJ, Markl M, Takebayashi S, Shimaoka T, Gorman JH 3rd, Gorman RC, Pilla JJ.: Directed epicardial assistance in ischemic cardiomyopathy: Flow and function using cardiac magnetic resonance imaging. Ann Thorac Surg 96(2): 577-85, Aug 2013.

Witschey WR, Cocosco CA, Gallichan D, Schultz G, Weber H, Welz A, Hennig J, Zaitsev M. : Localization by nonlinear phase preparation and k-space trajectory design. Magnetic Resonance Med 67(6): 1620-32, June 2012 Notes: doi: 10.1002/mrm.23146. Epub 2011 Nov 29.

Ferrari VA, Witschey WR, Zhou R.: Cardiac magnetic resonance assessment of myocardial fibrosis: honing new clinical tools. Circ Cardiovasc Imaging. Page: 604-6, Nov. 2011.

Schultz, G, Weber H, Gallichan D, Witschey W, Welz A, Cocosco C, Hennig J, Zaitsev M. : Radial imaging with multipolar magnetic encoding fields. IEEE Trans Med Imag. Page: 2134-45, Dec. 2012.

Schultz G, Weber H, Gallichan D, Witschey W, Welz A, Cocosco C, Hennig J, Zaitsev M.: Radial imaging with multipolar magnetic encoding fields. IEEE Trans Med Imag. Page: 2134-45, Dec 2011.

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Last updated: 08/02/2016
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