Faculty & Staff

Seung Cheol Lee, Ph.D.

faculty photo
Research Assistant Professor of Radiology
Department: Radiology

Contact information
B6 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-746-7387
Fax: 215- 573-2113
B.S. (Physics)
Korea Advanced Institute of Science and Technology, 1993.
M.S. (Solid State Physics)
Korea Advanced Institute of Science and Technology, 1995.
Ph.D. (Solid State Physics)
Korea Advanced Institute of Science and Technology, 2001.
Post-Graduate Training
Postdoc in Biophysics, Korea Basic Science Institute, 2001-2004.
Postdoc in Radiology, University of Pennsylvania, 2004-2007.
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Description of Research Expertise

MRI and MRS of cancer cells, animal models and human patients
Prediction and early detection of therapeutic response in non-Hodgkin's lymphoma

Selected Publications

Arias-Mendoza, F., Payne, G.S., Zakian, K., Stubbs, M., O'Conner, O.A., Mojahed, H., Smith, M.R., Schwarz, A.J., Shukla-Dave, A., Howe, F., Poptani, H., Lee, S.C., Pettengel ,R., Schuster, S.J., Cunningham, D., Heerschap, A., Glickson, J.D., Griffiths, J.R., Koutcher, J.A., Leach, M.O., Brown, T.R. : Noninvasive Phosphorus Magnetic Resonance Spectroscopic Imaging Predicts Outcome to First-line Chemotherapy in Newly Diagnosed Patients with Diffuse Large B-Cell Lymphoma. Academic Radiology 20(9): 1122-1129, September 2013.

Xu, H.N., Zhao, H., MIR, T.A., Lee, S.C., Feng, M., Choe, R., Glickson, J.D., Li, L.Z.: CHOP therapy induced mitochondrial redox state alteration in non-Hodgkin's lymphoma xenografts. Journal of Innovative Optical Health Sciences 6(2): 1350011, April 2013.

Nath, K., Nelson, D.S., Ho, A., Lee, S.C., Darpolar, M., Pickup, S., Zhou, R., Heitjan, D.F., Leeper, D.B., Glickson, J.D.: 31P and 1H MRS of DB-1 Melanoma Xenografts: Lonidamine Selectively Decreases Tumor Intracellular pH and Energy Status and Sensitizes Tumors to Melphalan. NMR in Biomedicine 26(1): 98-105, January 2013.

Lee, S.C., Marzec, M., Liu, X., Wehrli, S., Kantekure, K., Ragunath, P.N., Nelson, D.S., Delikatny, E.J., Glickson, J.D., Wasik, M.A.: Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma. NMR in Biomedicine 26(1): 106-114, January 2013.

Xu, H.N., Mir, T.A., Lee, S.C., Feng, M., Farhad, N., Choe, R., Glickson, J.D., Li, L.Z. : Mapping the Redox State of CHOP-Treated Non-Hodgkin's Lymphoma Xenografts in Mice. Advances in Experimental Medicine and Biology 789: 243-249, January 2013.

Lee, S.C., Arias-Mendoza, F., Poptani, H., Delikatny, E.J., Wasik, M., Marzec, M., Schuster, S.J., Nasta, S.D., Svoboda, J., Goldstein, S.C., Glickson, J.D. : Prediction and early detection of response by NMR spectroscopy and imaging. PET Clinics 7: 119-126, January 2012.

Lee, S.C., Potani, H., Delikatny, E.J., Pickup, S., Nelson, D.S., Schuster, S.J., Nasta, S.D., Svoboda, J., Goldstein, S.C., Wallace, S.G., Loevner, L.A., Mellon, E.A., Reddy, R., Glickson, J.D.: NMR Metabolic and Physiological Markers of Therapeutic Response. Advances in Experimental Medicine and Biology 915: 129-135, January 2011.

Lee, S.C., Poptani, H., Pickup, S., Jenkins, W.T., Kim, S., Koch, C.J., Delikatny, E.J., Glickson, J.D.: Early detection of radiation response in non-Hodgkin’s lymphoma xenografts by 1H MR spectroscopy and imaging. NMR in Biomedicine 23(6): 624-632, July 2010.

Mellon, M.A., Lee, S.C., Pickup, S., Kim, S., Goldstein, S.C., Floyd, T.F., Poptani, H., Delikatny, E.J., Reddy, R., Glickson, J.D. : Detection of lactate with a Hadamard slice selected, selective multiple quantum coherence, chemical shift imaging sequence (HDMD-SelMQC-CSI) on a clinical MRI scanner: Application to tumors and muscle ischemia. Magnetic Resonance in Medicine 62: 1404-1413, December 2009.

Lee, S.C., Kim, K., Kim, J., Yi, J.H., Lee, S., Cheong, C.: MR microscopy of micron scale structures. Magnetic Resonance Imaging 27: 828-833, July 2009.

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Last updated: 01/25/2015
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