Faculty & Staff

Despina Kontos, Ph.D.

faculty photo
Assistant Professor of Radiology
Department: Radiology

Contact information
Computational Breast Imaging Group (CBIG)
University of Pennsylvania, Department of Radiology
3600 Market St. Suite 360
Philadelphia, PA 19104
Fax: 215-614-0266
Lab: 215-615-0827
Education:
B.Eng. (Computer Engineering and Informatics )
University of Patras, Greece, 2000.
M.Sc. (Computer and Information Sciences )
Temple University, Philadelphia PA , 2003.
Ph.D. (Computer and Information Sciences )
Temple University, Philadelphia PA , 2006.
Post-Graduate Training
Fellow in Basic Radiologic Sciences, Radiological Society of North America (RSNA), Department of Radiology, University of Pennsylvania, Philadelphia PA (Research Fellowship) , 2006-2007.
Fellow in Basic Radiologic Sciences, Radiological Society of North America (RSNA), Department of Radiology, University of Pennsylvania, Philadelphia PA (Research Fellowship) , 2007-2008.
Fellow in Radiology-Physics and Breast Imaging, Susan G. Komen for the Cure Foundation, Department of Radiology, University of Pennsylvania, Philadelphia PA (Research Fellowship), 2008-2010.
Certifications
Clinical Research Certificate, Center for Clinical Epidemiology and Biostatistics (CCEB) University of Pennsylvania, Philadelphia PA, 2009.
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Description of Research Expertise

Biomedical image analysis; Quantitative imaging biomarkers; Pattern recognition; Identification, characterization and validation of imaging biomarkers; Evaluation of genotype to phenotype associations via imaging; Integrated diagnostics; Risk prediction; Personalized screening, prognostication and treatment of breast cancer.

Selected Publications

A.B. Ashraf, D. Daye, S. Gavenonis, C. Mies, M. Feldman, M. Rosen, D. Kontos: Identification of intrinsic radio-phenotypes for breast cancer tumors: Preliminary associations with gene expression profiles. Radiology 2014 (accepted).

S.Wu, S.P. Weinstein, E.F. Conant, D. Kontos: Automated fibroglandular tissue segmentation and volumetric density estimation in breast MRI using an atlas-aided fuzzy C-means method Medical Physics 40(12), 2013 (in press).

A. Ashraf, S. Gavenonis, D. Daye, C. Mies, M. Feldman, M.A. Rosen, and D. Kontos: A Multichannel Markov Random Field Framework for Tumor Segmentation with an Application to Classification of Gene Expression-based Breast Cancer Recurrence Risk. IEEE Transactions on Medical Imaging 32(4): 637-48, April 2013.

B.M. Keller, D.L. Nathan, Y. Wang, Y. Zheng, J.C. Gee, E.F. Conant, D. Kontos: Estimation of Breast Percent Density in Raw and Processed Full Field Digital Mammography Images via Adaptive Fuzzy C-means Clustering and Support Vector Machine Segmentation. Medical Physics 39(8): 4903-17, Aug 2012.

G. Karemore, B. Keller, H. Oh, J. Tchou, M. Nielsen, E. Conant, D. Kontos: Mammographic Parenchymal Texture Analysis for Estrogen-Receptor Subtype Specific Breast Cancer Risk Estimation. Proceedings of International Workshop on Breast Imaging (IWDM), Lecture Notes in Computer Science (LNCS). A.D.A. Maidment, P.R. Bakic, S.Gavenonis (eds.). Springer-Verlag Berlin Heidelberg 7361: 596–603, June 2012.

D. Kontos, L. Ikejimba, P.R. Bakic, A.B. Troxel,E.F. Conant, A.D.A. Maidment: Digital Breast Tomosynthesis Parenchymal Texture Analysis: Comparison with Digital Mammography and Implications for Cancer Risk Assessment. Radiology 261(1): 80-91, Oct 2011

D. Kontos, P.R. Bakic, A-K. Carton, A.B. Troxel, E.F. Conant, A.D.A Maidment: Parenchymal texture analysis in digital breast tomosynthesis for breast cancer risk estimation: A preliminary study Academic Radiology 16(3): 283-298, March 2009.

P.R. Bakic, A-K. Carton, D. Kontos, C. Zhang, A.B. Troxel, A.D.A. Maidment: Breast percent density estimation from mammograms and central tomosynthesis projections. Radiology 252(1): 40-9, July 2009.

V. Megalooikonomou, M. Barnathan, D. Kontos, P.R. Bakic, A.D.A Maidment: A representation and classification scheme for tree-like structures in medical images: Analyzing the branching pattern of ductal trees in x-ray galactograms IEEE Transactions on Medical Imaging 28(4): 487-93, April 2009.

D. Kontos and V. Megalooikonomou: Fast and Effective Characterization for Classification and Similarity Searches of 2D and 3D Spatial Region Data. Pattern Recognition 38(11): 1831-1846, November 2005.

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Last updated: 01/31/2014
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