Faculty & Staff

Despina Kontos, Ph.D.

faculty photo
Assistant Professor of Radiology
Department: Radiology

Contact information
Computational Breast Imaging Group (CBIG)
University of Pennsylvania, Department of Radiology
3600 Market St. Suite 360
Philadelphia, PA 19104
Fax: 215-614-0266
Lab: 215-615-0827
Education:
B.Eng. (Computer Engineering and Informatics )
University of Patras, Greece, 2000.
M.Sc. (Computer and Information Sciences )
Temple University, Philadelphia PA , 2003.
Ph.D. (Computer and Information Sciences )
Temple University, Philadelphia PA , 2006.
Post-Graduate Training
Fellow in Basic Radiologic Sciences, Radiological Society of North America (RSNA), Department of Radiology, University of Pennsylvania, Philadelphia PA (Research Fellowship) , 2006-2007.
Fellow in Basic Radiologic Sciences, Radiological Society of North America (RSNA), Department of Radiology, University of Pennsylvania, Philadelphia PA (Research Fellowship) , 2007-2008.
Fellow in Radiology-Physics and Breast Imaging, Susan G. Komen for the Cure Foundation, Department of Radiology, University of Pennsylvania, Philadelphia PA (Research Fellowship), 2008-2010.
Certifications
Clinical Research Certificate, Center for Clinical Epidemiology and Biostatistics (CCEB) University of Pennsylvania, Philadelphia PA, 2009.
Total Leadership Program, an innovative program developed by Dr. Stewart Friedman at Wharton School of the University of Pennsylvania, offered as part of an NIH study to promote women’s success in Academic Medicine, Philadelphia PA., 2010.
Interpersonal Dynamics Training, offered by the office of Organization Effectiveness on personality styles and group dynamics using the the Myers-Briggs Type Indicator, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA., 2014.
Research Mentor Training, a Course Series of six two-hour Case-Based training sessions designed to enhance specific skills in being an effective Mentor, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. , 2014.
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Description of Research Expertise

Biomedical image analysis; Quantitative imaging biomarkers; Pattern recognition; Identification, characterization and validation of imaging biomarkers; Evaluation of genotype to phenotype associations via imaging; Integrated diagnostics; Risk prediction; Personalized screening, prognostication and treatment of breast cancer.

Selected Publications

Ou Y, Weinstein SP, Conant EF, Englander S, Da X, Gaonkar B, Hsieh MK, Rosen M, DeMichele A, Davatzikos C, Kontos D: Deformable registration for quantifying longitudinal tumor changes during neoadjuvant chemotherapy. Magnetic Resonance in Medicine (MRM) 2014 (in press).

A.B. Ashraf, D. Daye, S. Gavenonis, C. Mies, M. Feldman, M. Rosen, D. Kontos: Identification of intrinsic radio-phenotypes for breast cancer tumors: Preliminary associations with gene expression profiles. Radiology 272(2): 374-84, Aug 2014.

S.Wu, S.P. Weinstein, E.F. Conant, D. Kontos: Automated fibroglandular tissue segmentation and volumetric density estimation in breast MRI using an atlas-aided fuzzy C-means method Medical Physics 40(12): 122302, Dec 2013.

A. Ashraf, S. Gavenonis, D. Daye, C. Mies, M. Feldman, M.A. Rosen, and D. Kontos: A Multichannel Markov Random Field Framework for Tumor Segmentation with an Application to Classification of Gene Expression-based Breast Cancer Recurrence Risk. IEEE Transactions on Medical Imaging 32(4): 637-48, April 2013.

B.M. Keller, D.L. Nathan, Y. Wang, Y. Zheng, J.C. Gee, E.F. Conant, D. Kontos: Estimation of Breast Percent Density in Raw and Processed Full Field Digital Mammography Images via Adaptive Fuzzy C-means Clustering and Support Vector Machine Segmentation. Medical Physics 39(8): 4903-17, Aug 2012.

D. Kontos, L. Ikejimba, P.R. Bakic, A.B. Troxel,E.F. Conant, A.D.A. Maidment: Digital Breast Tomosynthesis Parenchymal Texture Analysis: Comparison with Digital Mammography and Implications for Cancer Risk Assessment. Radiology 261(1): 80-91, Oct 2011

D. Kontos, P.R. Bakic, A-K. Carton, A.B. Troxel, E.F. Conant, A.D.A Maidment: Parenchymal texture analysis in digital breast tomosynthesis for breast cancer risk estimation: A preliminary study Academic Radiology 16(3): 283-298, March 2009.

P.R. Bakic, A-K. Carton, D. Kontos, C. Zhang, A.B. Troxel, A.D.A. Maidment: Breast percent density estimation from mammograms and central tomosynthesis projections. Radiology 252(1): 40-9, July 2009.

V. Megalooikonomou, M. Barnathan, D. Kontos, P.R. Bakic, A.D.A Maidment: A representation and classification scheme for tree-like structures in medical images: Analyzing the branching pattern of ductal trees in x-ray galactograms IEEE Transactions on Medical Imaging 28(4): 487-93, April 2009.

D. Kontos and V. Megalooikonomou: Fast and Effective Characterization for Classification and Similarity Searches of 2D and 3D Spatial Region Data. Pattern Recognition 38(11): 1831-1846, November 2005.

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Last updated: 11/13/2014
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