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He Nucleus Xu, PhD

faculty photo
Research Assistant Professor of Radiology
Senior Research Investigator, Department of Radiology, University of Pennsylvania
Technical Director, Britton Chance Laboratory of Redox Imaging, Johnson Research Foundation, Department of Biochemistry and Biophysics, University of Pennsylvania
Department: Radiology

Contact information
B6 Blockley Hall, 423 Guardian Drive
& Rm 171 John Morgan Bldg, 3700 Hamilton Walk
Philadelphia, PA 19104
Office: 215-573-7608
BS (Physics)
Ningxia University, Yinchuan, China, 1983.
MS (Optics)
Anhui Optics and Fine Mechanics Institute, Chinese Academy of Sciences, Hefei, China, 1988.
MS (Chemistry)
Drexel University, 1993.
PhD (Chemistry)
Drexel University, 1999.
Post-Graduate Training
Postdoctoral Fellow, University of Pennsylvania, Department of Radiology, 2010-2014.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Xu, He N.*, Tchou, Julia., Feng, Min, Zhao, Huaqing, Li, Lin Z*. : Optical redox imaging indices discriminate human breast cancer from normal tissues. J Biomed Opt 21: 114003, 2016 Notes: *corresponding author.

Xu, H. N.*, Li, L. Z.: Quantitative redox imaging biomarkers for studying tissue metabolic state and its heterogeneity. J Innov Opt Health Sci 7(2): 1430002-1-20, 2014 Notes: *corresponding author.

Sun, Nannan, Xu, He N., Luo, Qingming, Li, Lin Z.: Potential indexing of the invasiveness of breast cancer cells by mitochondrial redox ratios. Adv Exp Med Biol 923: 121-127, 2016.

Li, L. Z., Zhou, R., Xu, H. N., Moon, L., Zhong, T., Kim, E. J., Qiao, H., Reddy, R., Leeper, D., Chance, B., Glickson, J. D.: Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potential. Proc Natl Acad Sci USA 106(16): 6608-13, 2009.

Xu, He N., Nioka, Shoko, Glickson, Jerry D., Chance, Britton, Li, Lin Z.: Quantitative mitochondrial redox imaging of breast cancer metastatic potential. J Biomed Opt. SPIE, 15(3): 036010, 2010.

Xu, H. N., Zheng, G., Tchou, J., Nioka, S., Li, L. Z.: Characterizing the metabolic heterogeneity in human breast cancer xenografts by 3D high resolution fluorescence imaging. SpringerPlus 2(1): 73, 2013.

Cai, Kejia, Xu, He N., Singh, Anup, Moon, Lily, Haris, Mohammad, Reddy, Ravinder, Li, Lin Z.: Breast cancer redox heterogeneity detectable with chemical exchange saturation transfer (CEST) MRI. Mol Imaging Biol 16(5): 670-9, 2014.

Xu, H. N., Nioka, S., Li, L. Z.: Imaging heterogeneity in the mitochondrial redox state of premalignant pancreas in the pancreas-specific PTEN-null transgenic mouse model. Biomarker Research 1: 6, 2013.

Xu, He N., Feng, Min, Moon, Lily, Dolloff, Nathan, El-Deiry, Wafik, Li, Lin Z.: Redox imaging of the p53-dependent mitochondrial redox state in colon cancer ex vivo. J Innov Opt Health Sci 06: 1350016, 2013.

Xu, H. N., Zhao, H., Mir, T. A., Lee, S. C., Feng, M., Choe, R., Glickson, J. D., Li, L. Z.: CHOP therapy induced mitochondrial redox state alteration in non-hodgkin's lymphoma xenografts. J Innov Opt Health Sci 6: 1350011, 2013.

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Last updated: 12/19/2017
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