Faculty & Staff

Gregory J. Nadolski, M.D.

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Assistant Professor of Radiology at the Hospital of the University of Pennsylvania
Co-Director, Penn Image Guided Interventions (PIGI) Laboratory
Active Radiologist, Pennsylvania Hospital
Active Radiologist, Penn Presbyterian Medical Center
Attending Radiologist, Philadelphia Veteran's Affairs Medical Center
Attending Radiologist, Hospital of the University of Pennsylvania
Center for Lymphatic Imaging and Interventions, University of Pennsylvania
Department: Radiology

Contact information
Hospital of the University of Pennsylvania
Department of Radiology
1 Silverstein
3400 Spruce Street
Philadelphia, PA 19104
Office: 215.662.6839
Fax: 215.615.3545
Education:
B.S. (Biochemistry)
University of Wisconsin, Madison, WI , 2001.
M.D. (Medicine)
Indiana University School of Medicine, Indianapolis, IN , 2007.
Post-Graduate Training
Intern, Surgery, DIRECT Pathway, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA , 2007-2009.
Resident, Diagnostic Radiology, DIRECT Pathway, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA , 2009-2011.
Fellow, Interventional Radiology, DIRECT Pathway, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA , 2011-2012.
Resident, Diagnostic Radiology, DIRECT Pathway, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA , 2012-2013.
Certifications
ACLS certified , 2007.
American Board of Radiology , 2013.
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Description of Clinical Expertise

My research and clinical interests include multimodality therapies for the treatment of hepatocellular carcinoma and liver dominant metastatic cancer.

I have initiated two clinical trials at the Hospital of the University of Pennsylvania for treating hepatocellular carcinoma. One involves combining transcatheter embolization with external beam radiation, and the other combines transcatheter embolization with an investigational oral chemotherapeutics.

Clinical Trials:
1. A Pilot Trial of Transarterial Chemoembolization With or Without Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma Patients Awaiting Liver Transplantation, Hospital of the University of Pennsylvania (UPCC16213)

2. Phase I-II Clinical Trial of the Safety of Hydroxychloroquine Combined with Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma, Hospital of the University of Pennsylvania (UPCC22213)

My other area of clinical and research interest is lymphatic injury, dysfunction, and malformations. Clinically, I perform thoracic duct embolization to treat chylothorax. I participate in research investigating novel lymphatic interventions to treat chylothorax, chylous ascites, refractory ascites and protein losing enteropathy.

Description of Research Expertise

In addition to my research investigating lymphatic interventions and multimodality cancer therapies, I also conduct research on vascular remodeling as it relates to hemodialysis access malfunction and peripheral arterial disease.

In this research, I am investigating a minimally invasive near infrared imaging system to evaluate hemodialysis access. The goal of this research is to detect changes in blood vessels that lead to stenosis before it becomes symptomatic. Detection of such changes at any early stage could improve development and monitor response of therapies to treat vascular disease.

Selected Publications

Nadolski, G and Stavropoulos, SW: Chapter 49: Renal Angiomyolipomas. Embolization Therapy: Principles and Clinical Applications. Marcelo Guimaraes, MD, Riccardo Lencioni, MD, and Gary Siskin, MD (eds.). Lippincott, Williams, & Wilkins, 2015.

Weber, Charles, Nadolski, Gregory, Soulen, Michael: Effect of distance from the hepatocaval junction (HCJ) to the hepatic venous (HV) end of transjugular intrahepatic portosystemic shunt (TIPS) on long-term patency of PTFE-covered TIPS. RSNA Abstract December 2014.

Weber, Charles, Nadolski, Gregory, Soulen, Michael: Effect of distance from the hepatocaval junction (HCJ) to the hepatic venous (HV) end of transjugular intrahepatic portosystemic shunt (TIPS) on long-term patency of PTFE-covered TIPS. American Association of Liver Disease Annual Meeting November 2014 Boston, MA November 2014.

Christina Jacovides, Gregory Nadolski, Steven R. Allen, Niels D. Martin, Daniel N. Holena, Patrick M. Reilly, Scott Trerotola, Lew Kaplan, Jose L Pascual: ARTERIOGRAPHY FOR LOWER GI BLEEDING: DOES A PRECEDING ABDOMINAL CT ANGIOGRAM IMPROVE BLEED IDENTIFICATION AND OUTCOME? American Association for the Surgery of Trauma (Presented at 73rd Annual Meeting of AAST and Clinical Congress of Acute Care Surgery to be held in Philadelphia, PA) September 2014.

N. Harrison, S. Hunt, G. Nadolski, C.N. Weber, M. Knaus, M.C. Soulen, C. Simon, T.P. Gade: Superselective trans-arterial embolization in a translational rat model of hepatocellular carcinoma. World Conference on Interventional Oncology Annual Meeting May 2014 NYC, NY May 2014 Notes: Oral Presentation.

S. Hunt, T. Bittermann, M. Hoteit, G. Nadolski: Definitive locoregional therapy versus neoadjuvant locoregional therapy and transplant for unresectable very small hepatocellular carcinoma World Conference on Interventional Oncology May 2015, NYC, NY May 2014 Notes: Poster Presentation.

Nadolski Gregory, Mondschein Jeffrey I, Shlansky-Goldberg Richard D, Stavropoulos S William, Soulen Michael C, Dagli Mandeep S, Clark Timothy W I, Trerotola Scott O: Diagnostic yield of transjugular liver biopsy samples to evaluate for infectious etiology of liver dysfunction in bone marrow transplant recipients. Cardiovascular and interventional radiology 37(2): 471-5, Apr 2014.

N. Harrison, S. Hunt, G. Nadolski, C.N. Weber, M. Knaus, M.C. Soulen, C. Simon, T.P. Gade: Superselective trans-arterial embolization in a translational rat model of hepatocellular carcinoma. Journal of Interventional of Radiology 25, March 2014 Notes: Presented at Society of Interventional Radiology Annual Meeting 2014 San Diego, CA.

S. Hunt, T. Bittermann, M. Hoteit, G. Nadolski: Definitive locoregional therapy versus neoadjuvant locoregional therapy and transplant for unresectable very small hepatocellular carcinoma. Journal of Interventional Radiology 25: S112–S113, March 2014 Notes: Presented at Society of Interventional Radiology Annual Meeting 2014 San Diego, CA.

C. Chao, M. Dagli, J. Mondschein, W. Stavropoulos, D. Sudheendra, G. Nadolski, M.C. Soulen: Effect of substituting 50% isovue for sterile water as the delivery medium for SIR-SPHERES: improved dose delivery and decreased incidence of stasis. Journal of Interventional Radiology 25: S89, March 2014 Notes: Presented at the Society of Interventional Radiology Annual Meeting 2014 San Diego, Ca.

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Last updated: 08/14/2014
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