Faculty & Staff

Eric Wickstrom, Ph.D.

faculty photo
Adjunct Professor of Radiology
Department: Radiology

Contact information
Laboratory of Molecular Design, Department of Biochemistry & Molecular Biology, Thomas Jefferson University, Bluemle Life Sciences Bldg 219, 233 S. 10th St.
Philadelphia, PA 19107-5441
Office: 215-955-4578
Fax: 215-955-4580
Lab: 215-955-4579
BS Honors (Biology)
California Institute of Technology, 1968.
Ph.D. (Chemistry)
University of California, Berkeley, 1972.
Post-Graduate Training
Research Associate, Chemistry, and Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, 1973-1974.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

nucleic acid chemistry, biophysical properties, functional interactions
oncogene mRNAs
neurological mRNAs

Selected Publications

Wampole, M.E., Kairys, J. C., Mitchell, E. P., Ankeny, M. L., Thakur, M. L., and Wickstrom, E.: Consistent surgeon evaluations of three-dimensional rendering of PET/CT scans of the abdomen of a patient with a ductal pancreatic mass. PLoS One 9: Epub ahead of print, Sept 2013.

Paudyal, B., Zhang, K., Chen, C.-P., Mehta, N., Wampole, M. E., Mitchell, E. P., Gray, B. D., Mattis, J. A., Pak, K.-Y., Thakur, M. L., and Wickstrom, E. : Determining efficacy of breast cancer therapy by PET imaging of HER2 mRNA. Nuclear Medicine and Biology 40: Epub ahead of print, Sept 2013.

Sanders JM, Wampole ME, Chen C, Sethi DD, Singh A, Dupradeau FY, Wang F, Gray BD, Thakur ML, Wickstrom E.: Effects of Hypoxanthine Substitution in Peptide Nucleic Acids Targeting KRAS2 Oncogenic mRNA Molecules: Theory and Experiment. J Phys Chem B. American Chemical Society, 117: Epub ahead of print, August 2013.

Thakur Mathew L, Zhang Kaijun, Berger Adam, Cavanaugh Barbara, Kim Sung, Channappa Chaitra, Frangos Andrea J, Wickstrom Eric, Intenzo Charles M: VPAC1 Receptors for Imaging Breast Cancer: A Feasibility Study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 54(7): 1019-25, Jul 2013.

Opitz Armin W, Czymmek Kirk J, Wickstrom Eric, Wagner Norman J: Uptake, efflux, and mass transfer coefficient of fluorescent PAMAM dendrimers into pancreatic cancer cells. Biochimica et biophysica acta 1828(2): 294-301, Feb 2013.

Sanders Jeffrey M, Wampole Matthew E, Thakur Mathew L, Wickstrom Eric: Molecular determinants of epidermal growth factor binding: a molecular dynamics study. PloS one 8(1): e54136, Jan 2013.

Thakur Mathew L, Zhang Kaijun, Paudyal Bishnuhari, Devakumar Devadhas, Covarrubias Maria Y, Chen Chang-po, Cheng Changpo, Gray Brian D, Wickstrom Eric, Pak Koon Y: Targeting apoptosis for optical imaging of infection. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 14(2): 163-71, Apr 2012.

Sethi Dalip, Chen Chang-Po, Jing Rui-Yan, Thakur Mathew L, Wickstrom Eric: Fluorescent peptide-PNA chimeras for imaging monoamine oxidase A mRNA in neuronal cells. Bioconjugate chemistry 23(2): 158-63, Feb 2012.

Sethi, D., Thakur, M. L., and Wickstrom, E. : Receptor-specific peptides for targeting of liposomal, polymeric, and dendrimeric nanoparticles in cancer diagnosis and therapy. Current Molecular Imaging 1(1): 3-11, 2012.

Wickstrom Eric, Chen Chang-Po, Devadhas Devakumar, Wampole Matthew, Jin Yuan-Yuan, Sanders Jeffrey M, Kairys John C, Ankeny Martha L, Hu Rui, Barner Kenneth E, Steiner Karl V, Thakur Mathew L: Three dimensional projection environment for molecular design and surgical simulation. Studies in health technology and informatics 163: 691-5, 2011.

back to top
Last updated: 08/30/2013
The Trustees of the University of Pennsylvania