My primary expertise is in MRI physics and engineering.
I have developed various new acquisition methods in MRI particularly in fMRI, Steady-State Free Precssion (SSFP), Arterial Spin Labeling (ASL), 7 T MRI areas.
I also have interests in investigating novel MRI contrast mechanism and have worked on susceptibility imaging and phase contrast imaging.
The primary applications for my research is various neurological disorders including Multiple Sclerosis and Traumatic Brain Injury.
Selected Publications
P van Gelderen, JA de Zwart, J Lee, P Sati, DS Reich, JH Duyn: Nonexponential T2* decay in white matter. Magn Reson Med 67: 110-117, 2012.
J Lee, K Shmueli, B-T Kang, B Yao, M Fukunaga, P van Gelderen, S Palumbo, F Bosetti, AC Silva, JH Duyn: The contribution of myelin to magnetic susceptibilty-weighted contrasts in high-field MRI of the brain. Neuroimage 59: 3967-3975, 2012.
J Lee: Guest editorial: Special issue on neuroimaging. International Journal of Imaging Systems and Technology 22(1): 1, 2012.
GT Buracas, Y Jung, J Lee, RB Buxton, EC Wong, TT Liu: On multiple alternating steady states induced by periodic spin phase perturbation waveforms. Magn Reson Med 2012.
TS Kim, J Lee, JH Lee, GH Glover, JH Pauly: Analysis of the BOLD Characteristics in Pass-Band bSSFP fMRI. International Journal of Imaging Systems and Technology 22(1): 23-32, 2012.
J Lee, M Fukunaga, JH Duyn: Improving contrast to noise ratio of resonance frequency contrast images (phase images) using balanced steady-state free precession. Neuroimage 54: 2779-88, 2011.
J Lee, P van Gelderen, LW Kuo, H Merkle, AC Silva, JH Duyn: T2*-based fiber orientation mapping. Neuroimage 57: 225-234, 2011.
Lee, J., Shmueli, K., Fukunaga, M., van Gelderen, P., Merkle, H., Silva, A. C., Duyn, J. H.: Sensitivity of MRI resonance frequency to the orientation of brain tissue microstructure. Proc Natl Acad Sci U S A 107(11): 5130-5, 2010.
Fukunaga, M., Li, T. Q., van Gelderen, P., de Zwart, J. A., Shmueli, K., Yao, B., Lee, J., Maric, D., Aronova, M. A., Zhang, G., Leapman, R. D., Schenck, J. F., Merkle, H., Duyn, J. H.: Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast. Proc Natl Acad Sci U S A 107(8): 3834-9, 2010.
Lee, J., Hirano, Y., Fukunaga, M., Silva, A. C., Duyn, J. H.: On the contribution of deoxy-hemoglobin to MRI gray-white matter phase contrast at high field. Neuroimage 49(1): 193-8, 2010.
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Last updated: 05/17/2012
The Trustees of the University of Pennsylvania