Penn Cardiovascular Institute

Heart and Vascular Faculty

faculty photo

Lawrence H. Frame, MD

Associate Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Veterans Affairs Medical Center
Cardiology Section (111C)
Room 8A166
University and Woodland Avenues
Philadelphia, PA 19104
Office: (215) 662-6810
B.A. (Applied Math)
Harvard College, 1971.
M.D. ( )
Harvard Medical School, 1975.
Post-Graduate Training
Intern in Medicine, New York University Medical Center, New York, NY, 1975-1976.
Resident, Medicine, Bellevue Hospital. New York, NY, 1976-1978.
Research and Clinical Fellow, Cardiology, Massachusetts General Hospital. Boston, MA, 1978-1980.
Research Fellow, Pharmacology, Columbia College of Physicians and Surgeons. New York, NY, 1980-1982.
American Board of Internal Medicine, 1978.
Subspecialty in Cardiovascular Diseases, 1981.
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Selected Publications

Rich M, McGarvey ML, Teener JW, Frame LH: ECG Changes during Septic Shock. Cardiology 97: 187-196, 2002.

Ingelmo C and Frame LH: Mechanisms for Site Dependent Differences in the Resetting Response Curve in Fixed Barrier Reentry. J. Cardiovascular Electrophysiology 11: 981-989, 2000.

Ingelmo C, Frame LH: The Stimulus Site Affects the Resetting Response Curve in Reentry. PACE 22: 833, 1999.

Fei H, Yazmajian D, Hanna MS, Frame LH: Termination of reentry by lidocaine in the tricuspid ring in vitro: Role of cycle length oscillation, fast use-dependent kinetics, and fixed block. Circ Res 80: 242-252, 1997.

Fei H, Frame LH: D-Sotalol terminates reentry by two mechanisms with different dependence on the duration of the excitable gap. J Pharmacol & Expt Ther 277: 174-185, 1996.

Frame LH, Rhee EK, Bernstein RC, Fei H: Reversal of reentry and acceleration due to double wave reentry: Two mechanisms for failure to terminate tachycardias by rapid pacing. J Am Coll Cardiol 28: 137-145, 1996.

Fei H, Hanna MS, Frame LH: Assessing the excitable gap: Implications for tachycardia termination by premature stimuli and antiarrhythmic drugs. Circulation 94: 2268-2277, 1996.

Hanna MS, Frame LH: Reflection as a mechanism of termination of reentry by premature stimulation in an atrial anatomic barrier model. Circulation 94 (SuppI): I-352, 1996.

Frame LH: The tricuspid ring model of atrial flutter. Recent Advances in Atrial Flutter. Waldo A, Touboul P (eds.). Futura Publishing Co. Inc., Mt. Kisco, NY, Page: 159-171, 1996.

Frame LH: Lessons from animal models of atrial arrhythmias. Cardiology Clinics on Atrial Fibrillation. Cardiology Clinics. DiMarco JP (eds.). W. B. Saunders Company, Philadelphia, 14: 471-481, November 1996.

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Last updated: 12/01/2006
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