J. Eduardo Rame, M.D., M.Phil
Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine
Contact information
Penn Medicine
Heart Failure, Mechanical Assist and Cardiac Transplant Center
Hospital of the University of Pennsylvania
2 East, Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104
Heart Failure, Mechanical Assist and Cardiac Transplant Center
Hospital of the University of Pennsylvania
2 East, Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-615-7949
Fax: 215-349-5603
Fax: 215-349-5603
Education:
B.S., M.S. (Molecular Biophysics and Biochemistry)
Yale College, 1990.
M.Phil (Statistics/Health Services Research)
Oxford University , 1996.
M.D. (Medicine)
Harvard Medical School , 1997.
B.S., M.S. (Molecular Biophysics and Biochemistry)
Yale College, 1990.
M.Phil (Statistics/Health Services Research)
Oxford University , 1996.
M.D. (Medicine)
Harvard Medical School , 1997.
Post-Graduate Training
Intern in Internal Medicine, University of Texas Southwestern, 1997-1998.
Resident in Internal Medicine, University of Texas Southwestern, 1998-2000.
Fellow in Cardiovascular Genomics, University of Texas Southwestern, 2000-2002.
Fellow in Cardiology, Johns Hopkins University School of Medicine and Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health , 2002-2004.
Fellow in Heart Failure/Heart Transplant, Johns Hopkins Hospital, 2004-2005.
Intern in Internal Medicine, University of Texas Southwestern, 1997-1998.
Resident in Internal Medicine, University of Texas Southwestern, 1998-2000.
Fellow in Cardiovascular Genomics, University of Texas Southwestern, 2000-2002.
Fellow in Cardiology, Johns Hopkins University School of Medicine and Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health , 2002-2004.
Fellow in Heart Failure/Heart Transplant, Johns Hopkins Hospital, 2004-2005.
Certifications
American Board of Internal Medicine (Internal Medicine), 2000.
American Board of Internal Medicine (Cardiovascular Disease), 2005.
American Board of Internal Medicine (Certification in Advanced Heart Failure and Cardiac Transplantation patients), 2010.
Permanent linkAmerican Board of Internal Medicine (Internal Medicine), 2000.
American Board of Internal Medicine (Cardiovascular Disease), 2005.
American Board of Internal Medicine (Certification in Advanced Heart Failure and Cardiac Transplantation patients), 2010.
Selected Publications
Raina, A, Seetha R, Gertz ZM, Woo YJ, Rame JE*, Kirkpatrick JN*: Postoperative Right Ventricular Failure After Left Ventricular Assist Device Placement is Predicted by Preoperative Echocardiographic Structural, Hemodynamic and Functional Parameters. Journal of Cardiac Failure 19(1): 16-24, January 2013.Satya Shreenvias, MD; Hansie Mathelier, MD; Kelly Epps, MD; Pavan Atluri, MD; J. Eduardo Rame, MD: VA ECMO for Cardiac Arrest and Severe Refractory Cardiogenic Shock. American Heart Association-Scientific Sessions, Los Angeles November 2012.
Patel AM, Adeseun GA, Ahmed I, Mitter N, Rame JE, Rudnick MR: Renal Failure in Patients with Left Ventricular Assist Devices. Clin J Am Soc Nephrol October 2012.
James C. Fang, Teresa DeMarco, MD, Michael M,. Givertiz, MD, Barry A. Borlaug, MD, Gregory D. Lewis, MD, J. Eduardo Rame, MD, Mphil, Mardi Gomberg-Maitland, MD, MSc, Srinivas Murali, MD, Robert P. Frantz, MD, Dana McGlothlin, MD, Evelyn M. Horn, MD, and Raymond L, Benza, MD: World Health Organization Pulmonary Hypertension Group 2: Pulmonary hypertension due to left heart disease in the adult-a summery statement from the Pulmonary Hypertension Council of the International Society for Heart and Lung Transplantation. The Journal of Heart and Lung Transplantation September 2012.
Rame, J. Eduardo: Chronic Heart Failure: A Reversible Metabolic Sydnrome? Circulation 125(23), June 2012.
J. Eduardo Rame and David Spragg: “Device Therapy for Systolic Ventricular Failure” Muscle: Fundamental Biology and Mechanisms of Disease Joseph A. Hill and Eric N. Olson (eds.). Elsevier, 2012.
Margulies KB and Rame JE: Adaptations to Pulsatile vs. Nonpulsatile VAD Support. Circulation Heart Failure August 2011.
Felkin LE, Dries DL, Birks EJ, Barton PJR, Rame JE : Changes in endoplasmic reticulum stress are associated with myocardial recovery using mechanical unloading and pharmacological therapy European Heart Journal August 2011 Notes: Presented at the European Society of Cardiology (ESC) Annual Scientific Sessions: Paris, France.
Krishnamoorthy A, Rame J E, Brown T, Ayers C R, Gupta S, Patel P C, Markham D W, Drazner M H.: Progression from Normal to Reduced Left Ventricular Ejection Fraction in Patients With Concentric Left Ventricular Hypertrophy After Long-Term Follow-Up. American Journal of Cardiology July 2011.
Rame J E, Barouch L A, Sack M N, Lynn E G, Abu Asab M, Tsokos M, Kern S J, Barb J, Munson P J, Halushka M K, Miller K L, Fox Talbot K, Zhang J, Hare J M, Solomon M A, Danner R L.: Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPAR{alpha}/PGC1{alpha} and thermogenic glycerolipid/fatty acid cycling. Physiological Genomics 43(12): 726-738, June 2011.