Penn Cardiovascular Institute

Heart and Vascular Faculty

faculty photo

Francis Edward Marchlinski, MD

Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
HUP
3400 Spruce Street
9 Founders Pavilion
Philadelphia, PA 19104-4283
Office: (215) 662-6005
Fax: (215) 662-2879
Education:
B.S. (Premedicine, Magna Cum Laude )
Pennsylvania State University, State College, 1973.
M.D.
University of Pennsylvania School of Medicine, 1976.
Post-Graduate Training
Intern in Medicine, Hospital of the University of Pennsylvania, 1976-1977.
Resident in Medicine, Hospital of the University of Pennsylvania, 1977-1979.
Research Fellow in Cardiology/Electrophysiology, Hospital of the University of PA. , 1979-1980.
Fellow in Cardiology, Hospital of the University of Pennsylvania, 1980-1982.
Certifications
Board of Medical Examiners (Diplomat), 1977.
American Board of Internal Medicine, 1979.
Cardiovascular Diseases - American Board of Internal Medicine, 1981.
Electrophysiology - American Board of Internal Medicine, 1992.
Electrophysiology - American Board of Internal Medicine, 2002.
Electrophysiology - American Baord of Internal Medicine, 2012.
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Description of Research Expertise

Electrophysiology of the human atria and ventricles
Mechanism of supraventricular and ventricular arrhythmias
Anatomic and electrophysiologic substrate of atrial and ventricular arrhythmias.
Catheter ablative therapy in atrial and ventricular arrhythmias
Device therapy in management of ventricular arrhythmias
Arrhythmogenic cardiomyopathy and cardiac arrhythmias

Description of Clinical Expertise

Diagnosis and management of supraventricular and ventricular arrhythmias
Substrate mapping and catheter ablation of atrial and ventricular arrhythmias.
Pacemaker therapy in management of bradycardias
Implantable defibrillator therapy in treating ventricular arrhythmias
Management of atrial and ventricular arrhythmias in arrhythmogenic cardiomyopathy (ARVC)
Evaluation and treatment of genetically determined arrhythmia syndromes
Evaluation of patients with unexplained syncope

Selected Publications

Aldhoon Bashar, Frankel David S, Hutchinson Mathew D, Callans David J, Epstein Andrew E, Dixit Sanjay, Riley Michael P, Lin David, Garcia Fermin C, Supple Gregory E, Cooper Joshua M, Bala Rupa, Deo Rajat, Zado Erica S, Marchlinski Francis E: Unipolar Voltage Abnormality is Associated with Greater Left Ventricular Dysfunction in Ischemic Cardiomyopathy. Journal of cardiovascular electrophysiology Nov 2013.

Pancholy Samir B, Sharma Parikshit S, Pancholy Dipti S, Patel Tejas M, Callans David J, Marchlinski Francis E: Meta-Analysis of Gender Differences in Residual Stroke Risk and Major Bleeding in Patients With Nonvalvular Atrial Fibrillation Treated With Oral Anticoagulants. The American journal of cardiology Nov 2013.

Aldhoon Bashar, Tzou Wendy S, Riley Michael P, Lin David, Callans David J, Hutchinson Mathew D, Dixit Sanjay, Garcia Fermin C, Zado Erica S, Marchlinski Francis E: Nonischemic cardiomyopathy substrate and ventricular tachycardia in the setting of coronary artery disease. Heart rhythm : the official journal of the Heart Rhythm Society 10(11): 1622-7, Nov 2013.

Carballeira Pol Lidia, Deyell Marc W, Frankel David S, Benhayon Daniel, Squara Fabien, Chik William, Kohari Maria, Deo Rajat, Marchlinski Francis E: Ventricular premature depolarization QRS duration as a new marker of risk for the development of ventricular premature depolarization-induced cardiomyopathy. Heart rhythm : the official journal of the Heart Rhythm Society Nov 2013.

Betensky Brian P, Kapa Suraj, Desjardins Benoit, Garcia Fermin, Callans David, Dixit Sanjay, Frankel David S, Hutchinson Mathew, Supple Gregory, Zado Erica S, Marchlinski Francis E: Characterization of Transseptal Activation during Septal Pacing: Criteria for Identification of Intramural VT Substrate in Nonischemic Cardiomyopathy. Circulation. Arrhythmia and electrophysiology 6(6): 1123-30, Oct 2013.

Strauss David G, Mewton Nathan, Verrier Richard L, Nearing Bruce D, Marchlinski Francis E, Killian Tony, Moxley John, Tereshchenko Larisa G, Wu Katherine C, Winslow Raimond L, Cox Christopher, Spooner Peter M, Lima Joao A C: Screening Entire Health System ECG Databases to Identify Patients at Increased Risk of Death. Circulation. Arrhythmia and electrophysiology 6(6): 1156-62, Oct 2013.

Riley M, Zado ES, Bala R, Callans D, Cooper J, Dixit S, Garcia F, Gerstenfeld E, Hutchinson M, Lin D, Patel V, Verdino R, Marchlinski FE.: Lack of uniform progression of endocardial scar in patients with right ventricular dysplasia/cardiomyopathy and ventricular tachycardia. Circ Arrhythm Electrophysiol 3(4): 332-338, June 2010.

Van Herendael Hugo, Garcia Fermin, Lin David, Riley Michael, Bala Rupa, Cooper Joshua, Tzou Wendy, Hutchinson Mathew D, Verdino Ralph, Gerstenfeld Edward P, Dixit Sanjay, Callans David J, Tschabrunn Cory M, Zado Erica S, Marchlinski Francis E: Idiopathic right ventricular arrhythmias not arising from the outflow tract: prevalence, electrocardiographic characteristics, and outcome of catheter ablation. Heart rhythm : the official journal of the Heart Rhythm Society 8(4): 511-8, Apr 2011.

Mountantonakis Stavros E, Frankel David S, Gerstenfeld Edward P, Dixit Sanjay, Lin David, Hutchinson Mathew D, Riley Michael, Bala Rupa, Cooper Joshua, Callans David, Garcia Fermin, Zado Erica S, Marchlinski Francis E: Reversal of outflow tract ventricular premature depolarization-induced cardiomyopathy with ablation: effect of residual arrhythmia burden and preexisting cardiomyopathy on outcome. Heart Rhythm 8(10): 1608-14, October 2011.

Park Robert E, Saghy Laszlo, Zado Erica S, Tschabrunn Cory M, Marchlinski Francis E: Influence of left ventricular hypertrophy on scar identification during bipolar voltage mapping. Journal of Interventional Cardiac Electrophysiology 34(1): 45-50, June 2012.

Gertz Zachary M, Raina Amresh, Saghy Laszlo, Zado Erica S, Callans David J, Marchlinski Francis E, Keane Martin G, Silvestry Frank E: Evidence of atrial functional mitral regurgitation due to atrial fibrillation: reversal with arrhythmia control. Journal of the American College of Cardiology 58(14): 1474-81, Sep 2011.

Supple Gregory E, Ren Jian-Fang, Zado Erica S, Marchlinski Francis E: Mobile thrombus on device leads in patients undergoing ablation: identification, incidence, location, and association with increased pulmonary artery systolic pressure. Circulation 124(7): 772-8, Aug 2011.

Haqqani Haris M, Tschabrunn Cory M, Tzou Wendy S, Dixit Sanjay, Cooper Joshua M, Riley Michael P, Lin David, Hutchinson Mathew D, Garcia Fermin C, Bala Rupa, Verdino Ralph J, Callans David J, Gerstenfeld Edward P, Zado Erica S, Marchlinski Francis E: Isolated septal substrate for ventricular tachycardia in nonischemic dilated cardiomyopathy: incidence, characterization, and implications. Heart Rhythm 8(8): 1169-76, Aug 2011.

Gaztanaga L, Frankel DS, Kohari M, Kondapalli L, Zado ES, Marchlinski FE.: Time to recurrence of atrial fibrillation influences outcome following catheter ablation. Heart Rhythm 10(1): 2-9, September 2012 Notes: [Epub ahead of print].

Leong-Sit Peter, Robinson Melissa, Zado Erica S, Callans David J, Garcia Fermin, Lin David, Dixit Sanjay, Bala Rupa, Riley Michael P, Hutchinson Mathew D, Cooper Joshua, Gerstenfeld Edward P, Marchlinski Francis E: Inducibility of atrial fibrillation and flutter following pulmonary vein ablation. Journal of cardiovascular electrophysiology 24(6): 617-23, Jun 2013.

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Last updated: 12/14/2014
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