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David C. Metz, M.D.

Professor of Medicine at the Hospital of the University of Pennsylvania
Co-director, GI Physiology laboratory, Hospital of the University of Pennsylvania
Director, Acid Peptic Disorders Specialty Program, Digestive and Liver Center, Hospital of the University of Pennsylvania
Associate Chief for Clinical Affairs, Division of Gastroenterology, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
3 Ravdin
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-4279
Fax: 215-662-6530
Education:
M.D.
University of Witwatersrand, South Africa, 1982.
Post-Graduate Training
Intern in Medicine and Surgery, Johannesburg General Hospital Witwatersrand University, Johannesburg, South Africa, 1983-1983.
Intern in Internal Medicine, Albert Einstein Medical Center, 1986-1988.
Fellowship in Gastroenterology, Georgetown VAMC-NIH Combined Program, 1989-1991.
Fellowship, NIH, NIDDK, Digestive Disease Branch, 1991-1993.
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Selected Publications

CT Lau, WB Gefter, DC Metz: Radiographic appearance of a catheter-free wireless esophageal pH probe. Am J Roentgenol 184: S40-42, 2005.

GL Shih, C Brensinger, DA Katzka, DC Metz: Postprandial esophageal integrated acidity is a reliable predictor of GERD. Aliment Pharmacol Therap 21: 1475-1482, 2005.

DC Metz, PB Miner, DM Heuman, Y Chen, M Sostek: Comparison of the effects of intravenously and orally administered esomeprazole on acid output in patients with symptoms of gastro-esophageal reflux disease. Aliment Pharmacol Therap 22: 813-821, 2005.

Metz DC, Comer GM, Soffer E, Forsmark CE, Cryer B, Chey W, Pisegna JR: Three year oral pantoprazole administration is effective for patients with Zollinger-Ellison syndrome and other hypersecretory conditions. Aliment Pharmacol Therap 23: 437-444, 2006.

Pratha V, Hogan DL, Lynn RB, Field B and Metz, DC: Intravenous Pantoprazole as Initial Treatment in Patients With Gastroesophageal Reflux Disease and a History of Erosive Esophagitis: A Randomized Clinical Trial. Dig Dis Sci 51: 1595-1601, 2006.

WC Blonski, GL Shih, CM Brensinger, DA Katzka, DC Metz. : Analysis of the acidity index and integrated intragastric acidity in 645 patients presenting with gastroesophageal reflux disease symptoms. Sc J Gastroenterol 41: 382-389, 2006.

Yang Y-X, Lewis JD, Epstein S, Metz DC: Chronic proton pump inhibitor therapy and hip fracture risk. JAMA 296: 1595-1601, 2006.

JD Lewis, BL Strom, SE Kimmel, J Farrar, DC Metz, C Brensinger, L Nessel, AR Localio: Predictors of recall of over-the-counter and prescription non-steroidal anti-inflammatory drug exposure. Pharmacoepidemiol Drug Saf 15: 39-45, 2006.

Howden C, Metz DC, Hunt B, Majid V, Kukulka M, Amer F, Samra N. : Dose-Response Evaluation of the Antisecretory Effect of Continuous Infusion Intravenous Lansoprazole Regimens over 48 Hours. Aliment Pharmacol Therap 23: 975-984, 2006.

Metz DC, Amer F, Hunt B, Majid V, Kukulka M. : Lansoprazole Regimens That Sustain Intragastric pH >6: An Evaluation of Intermittent Oral and Continuous IV Infusion Dosages. Aliment Pharmacol Therap 23: 985-995, 2006.

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Last updated: 01/23/2009
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