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David C. Metz, MBBCh (MD equivalent)

Professor of Medicine at the Hospital of the University of Pennsylvania
Co-Director, GI Physiology Laboratory, Hospital of the University of Pennsylvania
Director, Acid Peptic Disorders Specialty Program, Digestive and Liver Center, Hospital of the University of Pennsylvania
Co-Director , Penn Program for Swallowing Disorders
Associate Chief for Clinical Affairs, Division of Gastroenterology, Hospital of the University of Pennsylvania
Lead Physician, Hospital of the University of Pennsylvania, GI Division, Philadelphia, PA
Co-Director, Neuroendocrine Tumor Center, University of Pennsylvania
Full Clinical Member, Abramson Cancer Center, Cancer Therapeutics Program
Department: Medicine

Contact information
University of Pennsylvania Health System
Division of Gastroenterology
3400 Civic Center Boulevard
Perelman Center for Advanced Medicine
7 South Pavilion
Philadelphia, PA 19104
Office: 215-662-3541
Fax: 215-349-5915
King David High School , 1975.
University of Witwatersrand Medical School, Johannesburg, South Africa. , 1982.
Post-Graduate Training
Intern in General Medicine and General Surgery, Johannesburg General Hospital Witwatersrand University, Parktown, Johannesburg, South Africa, 1983-1983.
Private Practice , Athlone and Hanover Park, Capetown, South Africa, 1984-1984.
General Practice - locum tenens, State Alluvial Diamond Mine Hospital Alexander Bay, South Africa , 1984-1984.
Assistantship in General Practice, Johannesburg, South Africa , 1985-1985.
Internal Medicine - locum tenens, University College Hospital, London, England, General Medicine and Pulmonology , 1985-1985.
Private Practice - cardiac stress testing and radiology, Harley St. London, England, 1985-1985.
Casualty Officer, Johannesburg Hospital Emergency Room, Johannesburg, South Africa, 1985-1985.
Intern in Internal Medicine, Albert Einstein Medical Center, 1986-1988.
Fellowship in Gastroenterology, Georgetown VAMC-NIH Combined Program, 1989-1991.
Fellowship, NIH, NIDDK, Digestive Disease Branch, 1991-1992.
Senior Staff fellow, Digestive Diseases branch, NIDDK, NIK, 1991-1993.
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Selected Publications

Lau CT, Gefter WB, Metz DC: Radiographic appearance of a catheter-free wireless esophageal pH probe. Am J Roentgenol 184: S40-42, 2005.

Shih GL, Brensinger C, Katzka DA, Metz DC: Postprandial esophageal integrated acidity is a reliable predictor of GERD. Aliment Pharmacol Therap 21: 1475-1482, 2005.

Metz DC, Miner PB, Heuman DM, Chen Y, Sostek M: Comparison of the effects of intravenously and orally administered esomeprazole on acid output in patients with symptoms of gastro-esophageal reflux disease. Aliment Pharmacol Therap 22: 813-821, 2005.

Metz DC, Comer GM, Soffer E, Forsmark CE, Cryer B, Chey W, Pisegna JR: Three year oral pantoprazole administration is effective for patients with Zollinger-Ellison syndrome and other hypersecretory conditions. Aliment Pharmacol Therap 23: 437-444, 2006.

Pratha V, Hogan DL, Lynn RB, Field B, Metz DC: Intravenous Pantoprazole as Initial Treatment in Patients With Gastroesophageal Reflux Disease and a History of Erosive Esophagitis: A Randomized Clinical Trial. Dig Dis Sci 51: 1595-1601, 2006.

Blonski WC, Shih GL, Brensinger CM, Katzka DA, Metz DC: Analysis of the acidity index and integrated intragastric acidity in 645 patients presenting with gastroesophageal reflux disease symptoms. Sc J Gastroenterol 41: 382-389, 2006.

Yang YX, Lewis JD, Epstein S, Metz DC: Chronic proton pump inhibitor therapy and hip fracture risk. JAMA 296: 1595-1601, 2006.

Lewis JD, Strom BL, Kimmel SE, Farrar J, Metz DC, Brensinger C, Nessel L, Localio AR: Predictors of recall of over-the-counter and prescription non-steroidal anti-inflammatory drug exposure. Pharmacoepidemiol Drug Saf 15: 39-45, 2006.

Howden C, Metz DC, Hunt B, Majid V, Kukulka M, Amer F, Samra N. : Dose-Response Evaluation of the Antisecretory Effect of Continuous Infusion Intravenous Lansoprazole Regimens over 48 Hours. Aliment Pharmacol Therap 23: 975-984, 2006.

Metz DC, Amer F, Hunt B, Majid V, Kukulka M. : Lansoprazole Regimens That Sustain Intragastric pH >6: An Evaluation of Intermittent Oral and Continuous IV Infusion Dosages. Aliment Pharmacol Therap 23: 985-995, 2006.

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Last updated: 10/21/2015
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