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Gary Warren Falk, M.D., M.S.

Professor of Medicine at the Hospital of the University of Pennsylvania
Adjunct Faculty, Center for Clinical Epidemiology and Biostatistics
Clinical Co-Director, Joint Center for Digestive, Liver and Pancreatic Medicine, University of Pennsylvania, School of Medicine and the Children's Hospital of Philadelphia
Co-Director, GI Motility/Physiology Program, Hospital of the University of Pennsylvania, and Perelman Center for Advanced Medicine
Co-director, Joint Penn CHOP Center for Digestive, Liver and Pancreatic Disorders.
Co-director, GI Physiology Laboratory. Hospital of the University of Pennsylvania.
Member, Abramson Comprehensive Cancer Center. Cancer Control Research Program. Hospital of the University of Pennsylvania.
Department: Medicine

Contact information
Division of Gastroenterology
Department of Internal Medicine
Hospital of the University of Pennsylvania
9th Floor Penn Tower
One Convention Center Avenue
Philadelphia, PA 19104
Office: 215-615-4452
Fax: 215-349-5915
Education:
HS
Stuyvesant High School, New York, New York , 1972.
B.S. (Biology-Geology. Cum laude with high distinction)
University of Rochester, Rochester, NY, 1976.
M.D.
University of Rochester School of Medicine and Dentistry, Rochester, NY, 1980.
M.S. (Clinical Research)
Case Western Reserve University School of Medicine Clinical Scholars Program, Cleveland, Ohio, 2006.
Post-Graduate Training
Intern in Internal Medicine, George Washington University Medical Center, Washington, DC, 1980-1981.
Resident in Internal Medicine, George Washington University Medical Center, Washington, DC, 1981-1983.
Clinical Fellow in Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, 1983-1984.
Research Fellow in Gastroenterology. Studied immunocytochemistry of CCK processing intermediates in the brain. Dr. Stanley Watson, preceptor. Studied interaction of secretin and gastrointestinal motility. Dr Chung Owyang, preceptor., University of Michigan Medical Center, Ann Arbor, MI, 1984-1986.
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Description of Clinical Expertise

Esophageal diseases including Barrett's esophagus, eosinophilic esophagitis, GERD diagnosis and treatment, achalasia, motility abnormalities, extraesophageal GERD, dysphagia, esophageal cancer

Description of Other Expertise

Consultative gastroenterology
Upper endosccopy
Endoscopic dilation
Endoscopic mucosal resection
Radiofrequency ablation
Pneumatic dilation
Colonoscopy
Polypectomy
High resolution manometry
BRAVO pH
Impedance pH
Hydrogen breath tests
Urea breath tests

Description of Research Expertise

Barrett's esophagus: chemoprevention, detection, diagnosis, cancer prevention, epidemiology, risk stratification

Eosinophilic esophagitis: epidemiology, pediatric-adult transition, fibrosis

Endoscopy: advanced imaging

Selected Publications

Rieder F, Nonevski I, Ma J, Ouyang Z, West G, Protheroe C, Depetris G, Schirbel A, Lapinski J, Goldblum J, Bonfield T, Lopez R, Harnett K, Lee J, Hirano I, Falk G, Biancani P, Fiocchi C. : T-helper 2 Cyotkines, Transforming Growth Factor B1, and Eosinophil Products Induce Fibrogenesis and Alter Muscle Motility in Patients with Eosinophilic Esophagitis Gastroenterology January 2014 Notes: Epub ahead of print

Nieponice A, Badaloni AE, Jobe BA, Hoppo T, Pellegrini C, Velanovich V, Falk GW, Reavis K, Swanstrom L, Sharma VK, Nachman F, Ciotola FF, Caro LE, Cerisoli C, Cavadas D, FIgueroa LD, Pirchi D, Gibson M, Elizalde S, Cohen H. : Management of Early-Stage Esophageal Neoplasia (MESEN) Consensus. World J Surg 38: 96-105, 2014.

Canto MI, Anandasabapathy S, Brugge W, Falk GW, Dunbar KB, Zhang Z, Woods K, Almario JA, Schell U, Goldblum J, Maitra A, Montgomery E, Kiesslich R. : In vivo endomicroscopy improves detection of Barrett's esophagus-related neoplasia: a multicenter international randomized controlled trial (with video) Gastrointest Endosc 79: 211-21, 2014.

Anaparthy Rajeswari, Gaddam Srinivas, Kanakadandi Vijay, Alsop Benjamin R, Gupta Neil, Higbee April D, Wani Sachin B, Singh Mandeep, Rastogi Amit, Bansal Ajay, Cash Brooks D, Young Patrick E, Lieberman David A, Falk Gary W, Vargo John J, Thota Prashanti, Sampliner Richard E, Sharma Prateek: Association Between Length of Barrett's Esophagus and Risk of High-grade Dysplasia or Adenocarcinoma in Patients Without Dysplasia. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 11(11): 1430-6, Nov 2013.

Gaddam Srinivas, Singh Mandeep, Balasubramanian Gokulakrishnan, Thota Prashanthi, Gupta Neil, Wani Sachin, Higbee April D, Mathur Sharad C, Horwhat John D, Rastogi Amit, Young Patrick E, Cash Brooks D, Bansal Ajay, Vargo John J, Falk Gary W, Lieberman David A, Sampliner Richard E, Sharma Prateek: Persistence of nondysplastic Barrett's esophagus identifies patients at lower risk for esophageal adenocarcinoma: results from a large multicenter cohort. Gastroenterology 145(3): 548-53.e1, Sep 2013.

Enestvedt Brintha K, Lugo Ricardo, Guarner-Argente Carlos, Shah Pari, Falk Gary W, Furth Emma, Ginsberg Gregory G: Location, location, location: does early cancer in Barrett's esophagus have a preference? Gastrointestinal endoscopy 78(3): 462-7, Sep 2013.

Noti Mario, Wojno Elia D Tait, Kim Brian S, Siracusa Mark C, Giacomin Paul R, Nair Meera G, Benitez Alain J, Ruymann Kathryn R, Muir Amanda B, Hill David A, Chikwava Kudakwashe R, Moghaddam Amin E, Sattentau Quentin J, Alex Aneesh, Zhou Chao, Yearley Jennifer H, Menard-Katcher Paul, Kubo Masato, Obata-Ninomiya Kazushige, Karasuyama Hajime, Comeau Michael R, Brown-Whitehorn Terri, de Waal Malefyt Rene, Sleiman Patrick M, Hakonarson Hakon, Cianferoni Antonella, Falk Gary W, Wang Mei-Lun, Spergel Jonathan M, Artis David: Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis. Nature medicine 19(8): 1005-13, Aug 2013.

Gupta Milli, Iyer Prasad G, Lutzke Lori, Gorospe Emmanuel C, Abrams Julian A, Falk Gary W, Ginsberg Gregory G, Rustgi Anil K, Lightdale Charles J, Wang Timothy C, Fudman David I, Poneros John M, Wang Kenneth K: Recurrence of esophageal intestinal metaplasia after endoscopic mucosal resection and radiofrequency ablation of Barrett's esophagus: results from a US Multicenter Consortium. Gastroenterology 145(1): 79-86.e1, Jul 2013.

Guarner-Argente Carlos, Buoncristiano Thomas, Furth Emma E, Falk Gary W, Ginsberg Gregory G: Long-term outcomes of patients with Barrett's esophagus and high-grade dysplasia or early cancer treated with endoluminal therapies with intention to complete eradication. Gastrointestinal endoscopy 77(2): 190-9, Feb 2013.

Menard-Katcher P, Marks KL, Liacouras CA, Spergel JM, Yang YX, Falk GW. : The natural history of eosinophilic esophagitis in the transition from childhood to adulthood. Alimentary Pharmacology and Therapeutics 37: 114-121, 2013.

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Last updated: 05/01/2014
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