Division of General Internal Medicine

Division of General Internal Medicine
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Amanda B. Christini, MD

Assistant Professor of Clinical Medicine
Director, Strategic Initiatives, Penn Medicine Center for Health Care Innovation
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
Division of General Internal Medicine
Section of Hospital Medicine
3400 Spruce Street
Suite 2009 Penn Tower
Philadelphia, PA 19104
Office: 215-898-1720
Education:
BS (Biology)
Tufts University, 1997.
Post-Bac (Pre-Medical)
Georgetown University, 2003.
MD (Summa Cum Laude )
University of Pittsburgh School of Medicine, 2008.
Post-Graduate Training
Intern in Internal Medicine, Hospital of the University of Pennsylvania, 2008-2009.
Resident in Internal Medicine, Hospital of the University of Pennsylvania, 2009-2011.
Certifications
American Board of Internal Medicine, 2011.
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Description of Clinical Expertise

CLINICAL RESEARCH
2011 – present, Co-Principle Investigator: Phase 2 randomized, double-blind, placebo-controlled study of GS-5885, GS-9451, Tegobuvir and Ribavirin in interferon ineligible or intolerant subjects with chronic genotype 1a or 1b HCV infection

2011 – present, Co-Principle Investigator: Phase 2 randomized, double-blind, placebo-controlled study of GS-5885, GS-9451, Tegobuvir and Ribavirin in treatment-experienced subjects with chronic genotype 1a or 1b HCV infection

2007 Principal Investigator: Influenza vaccination and motivators among healthcare worker groups.

Description of Other Expertise

PROFESSIONAL EXPERIENCE
Maxygen, Inc. Redwood City CA 1999-2004
Consultant 2003-2004
Director, Business Development 2000-2003
Head, Business Development, Vaccines Business Unit 1999-2000
• Responsible and accountable for the following roles, reporting to President and CEO:
o Management of scientific and clinical teams responsible for product development,
o Corporate partnerships, license agreements, acquisitions and merger evaluations,
o Budget development and management, and
o Strategic planning, product portfolio management and resource allocation.
• Developed and implemented R&D plans for lead products with SVP, Clinical Development
• Led negotiations and closed deals with Aventis Pasteur, International AIDS Vaccine Initiative; contract manufacturers; university, government and corporate technology licenses and research agreements
• Managed collaborations with Aventis Pasteur, ALK-Abello, IAVI and $20M grant program with DARPA

Valentis, Inc. Burlingame, CA 1997-1999
Director, Business Development 1998-1999
Manager, Business Development 1998
Associate, Business Development 1997
• Responsible for business development for cardiovascular and oncology business units
• Led and closed multiple corporate partnerships, asset acquisitions and technology licenses
• Led integration of Business Development for Megabios in merger with GeneMedicine to form Valentis
• Developed and implemented technology acquisition strategy throughout the company

Massachusetts Institute of Technology
Office of Technology Licensing, Cambridge, MA 1995-1996
Licensing Associate
• Licensed biotechnology inventions to corporate partners and managed university patent portfolios

Selected Publications

Christini, AB: Why Universities Should Step Up in Venture Investing. Nature Biotechnology 30(10): 933-936, October 2012.

Christini, AB; King E: Evaluation of a neck mass in a returning traveler. Journal of the American Medical Association 2012.

Christini AB, Shutt KA, Byers KE: Influenza vaccination and motivators among healthcare worker groups. Infect Control Hosp Epidemiol 28(2): 171-7, Feb 2007.

Christini AB, Shutt KA, Byers KE: Influenza vaccination and motivators among healthcare worker groups Presented at the Infectious Diseases Society of America meeting, Toronto, Canada, October 2006.

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Last updated: 02/24/2014
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