Department of Hematology

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Selina M. Luger, M.D.

Associate Professor of Medicine at the Hospital of the University of Pennsylvania
Member
Chair, Chemotherapy Taskforce
Chair
Outpatient Clinic
Department: Medicine

Contact information
Hematology-Oncology
Perelman Center 2 West
34th and Civic Center Blvd
Philadelphia, PA 19104
Office: 2156141487
Fax: 2156624064
Education:
A.B. (Biochemistry)
Harvard University, 1982.
M.D. (Medicine)
McGill University, 1987.
Post-Graduate Training
Intern, Internal Medicine , Presbyterian University Hospital, Pittsburgh, 1987-1988.
Resident, Internal Medicine , Presbyterian University Hospital, Pittsburgh, 1988-1990.
Fellowship, Hematology-Oncology , University of Pennsylvania, Philadelphia, 1990-1993.
Certifications
ABIM/Internal Medicine, 1990.
Royal College of Physicians & Surgeons of Canada, 1990.
ABIM/Medical Oncology, 1993.
ABIM/Hematology, 2005.
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Description of Research Expertise

Leukemia, myelodysplastic syndrome, myeloproliferative disorders
MDS, AML, CML, ALL

Description of Clinical Expertise

hematologic malignancies, leukemia, AML, ALL, CML, myelodysplastic syndrome, MDS, myeloproliferative disorders, stem cell transplantation, bone marrow transplant

Selected Publications

Marks, David I., Paietta, Elisabeth M., Moorman, Anthony V., Richards, Susan M., Buck, Georgina, DeWald, Gordon, Ferrando, Adolfo, Fielding, Adele K., Goldstone, Anthony H., Ketterling, Rhett P, Litzow, Mark R, Luger, Selina M., McMillan, Andrew K, Mansour Marc, Rowe, Jacob M, Tallman, Martin S, Lazarus, Hillard: T-cell acute lymphoblastic leukemia in adults:clinical features, immunophenotype, cytogenetics and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993). Blood Oct 2009.

Fernandez HF, Sun Z, Yao X, Litzow MR, Luger SM, Paiette EM, Racevskis J, Dewald GW, Ketterling RP, Bennett JM, Rowe JM, Lazarus HM, Tallman MS: Anthracycline dose intensification in acute myeloid leukemia. New England Journal of Medicine 361(13): 1301-1303, September 2009.

Mato, AR, Fuchs, BD, Heitjan, DF, Mick, R, Halpern, SD, Shah, PD, Jacobs, S, Olson, E, Schuster, SJ, Ujjani, C, Chong, EA, Loren, AW, Miltiades, AN, Luger, SM: Utility of the systemic inflammatory response syndrome (SIRS) criteria in predicting the onset of septic shock in hospitalized patients with hematologic malignancies. Cancer Biology & Therapy 8(12): 1095-1100, JUN 15 2009.

Fielding, AK, Rowe, JM, Richards, SM, Buck, G, Moorman, AV, Durrant, IJ, Marks, DI, McMillan, AK, Litzow, MR, Lazarus, HM, Foroni, L, Dewald, G, Franklin, IM, Luger, SM, Paietta, E, Wiernik, PH, Tallman, MS, Goldstone, AH: Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG2993. Blood 113(19): 4489-4496, MAY 7 2009.

Tsai, D.E., Vogl, D, Wang, W, Reshef, R, Stadtmauer, E, Andreadis, C, Carlson, A, Luger, S: Effect of bexarotene on platelet counts in patients undergoing cancer treatment: An analysis of clinical trials in lung cancer and leukemia. ASCO Meeting Abstracts Page: e20533, May 20 2009.

Fernandez, H.F., Sun, Z., Litzow, M.R., Luger, S.M., Paietta, E.M., Dewald, G., Ketterling, R.P., Rowe, J.M., Lazarus, H.M., Tallman, M.S.: A randomized trial of anthracycline dose intensification during induction of younger patients with acute myeloid leukemia: results of Eastern Cooperative Oncology Group study E1900. ASCO Meeting Abstracts Page: 7003, May 20 2009.

Garcia-Manero, G, Luger, S, Venugopal, P, Maness, L, Wetzler, M, Coutre, S Stock, W, Borthakur, G, Chiao, J, Kantarjian, H: A randomized phast II study of sapacitabine, an oral nucleoside analogue in elderly patients with AML previously untreated or in first relapse or previously treated MDS. ASCO meeting Abstracts Page: 7021, May 20 2009.

Olin, R L., Vogl, D T., Porter, D L., Luger, S M., Schuster, S J., Tsai, D E., Siegel, D L., Cook, R J., Mangan, P A., Cunningham, K., Stadtmauer, E A.: Second auto-SCT is safe and effective salvage therapy for relapsed multiple myeloma. Bone Marrow Transplantation 43(5): 417-22, Mar 2009.

Kasner, Margaret T. Luger, Selina M.: Update on the therapy for myelodysplastic syndrome. [Review] [114 refs] American Journal of Hematology 84(3): 177-86, Mar 2009.

Goldstein, SC, Levine, B, Swith, J, Hinkle, J, Luger, S, Perl, A, Loren, A, Frey, N, Stadtmauer, E, Porter, DL, June, CH: Prophylactic Administration of Ex vivo Co-Stimulated Donor Lymphocyte Infusion (DLI) From Related and Unrelated Donors After Reduced Intensity conditioning for High Risk Hematologic Malignancies Biology of Blood And Marrow Transplantation 15(2 Suppl. 2): 363 February 2009.

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Last updated: 10/29/2009
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