Hematology Home >
- Faculty
J. Eric Russell, M.D.Associate Professor of Medicine
Department: Medicine
Contact information
316F Abramson Building
The Children's Hospital of Philadelphia 34th Street and Civic Center Boulevard Philadelphia, PA 19104
Office: 215-590-3880
Fax: 215-590-4834 Email: JERUSS@MAIL.MED.UPENN.EDU
Graduate Group Affiliations
Publications
Education:
B.A. (Chemistry: magna cum laude) Harvard University Cambridge, MA, 1980. M.D. (Medicine) Stanford University School of Medicine Palo Alto, CA , 1984.
Post-Graduate Training
Intern, Internal Medicine, Hospital of the University of Pennsylvania, 1984-1985. Resident, Internal Medicine, Hospital of the University of Pennsylvania, 1985-1987. Fellow, Hematology-Oncology, Hospital of the University of Pennsylvania, 1987-1991. Associate, Howard Hughes Medical Institute, University of Pennsylvania School of Medicine, 1989-1991.
Certifications
Permanent linkBoard Certification in Internal Medicine, 1987. Board Eligible in Hematology, 1989. Board Certification in Medical Oncology, 1989. Description of Research ExpertiseRESEARCH INTERESTSControl and function of human embryonic globin genes. Key words: Globin, embryonic, sickle cell anemia, thalassemia, mRNA, prothrombin. Description of Clinical ExpertiseHemoglobinopathies, thalassemias, sickle cell diseaseSelected PublicationsJiang, Y., Xu, X.-S., and Russell, J.E.: The high stability of [beta]-globin mRNA requires site-specific binding of factors that remodel the structure of its 3'UTR. The 8th Cooley's Anemia Symposium, New York Academy of Sciences, March 17-19 2005.Jiang, Y., Xu, X.-S., and Russell, J.E.: The high stability of human [beta]-globin mRNA is determined by a specific cis-element within its 3'UTR. 28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati, April 9-13 2005. He, Z., and Russell, J.E.: Evidence that differential stabilization of [beta]-like globin mRNAs is mediated by specific determinants in their 3'UTRs. 28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati, April 9-13 2005. He, Z. and Russell, J.E.: Anti-sickling effects of an endogenous human [alpha]-like globin. Nature Medicine 10: 365-7, 2004. Russell, J.E.: Adaptive post-transcriptional processes mitigate globin chain imbalance in [beta]-thalassemic erythrocytes. 27th Annual Meeting of the National Sickle Cell Disease Program, Los Angeles, April 18-21 2004 Notes: Oral presentation. He, Z., and Russell, J.E.: Co-expression of human [zeta] globin corrects the sickle phenotype in mouse models of sickle cell disease. 27th Annual Meeting of the National Sickle Cell Disease Program, Los Angeles, April 18-21 2004 Notes: Oral presentation. Frehm, E.J., Russell, J.E., and Gow, A.J.: Genetic and pharmacologic modulation of nitric oxide-hemoglobin reactivity. Eastern Society for Pediatric Research, Old Greenwich CT, March 26-28 2004 Notes: Oral presentation. He, Z., and Russell, J.E.: Effect of [zeta]-globin substitution on the O2-transport properties of Hb S in vivo and in vitro Biochem. Biophys. Res. Comm. 325: 1376-82, 2004. Russell, J.E.: Hemoglobinopathies and thalassemias. Medical Knowledge Self-Assessment Program 13. P.E. Epstein (eds.). Page: 30-32, 2003. Ozelo, M.C., Annichino-Bizzacchi, J.M., Pollak, E.S., and Russell, J.E.: Rapid detection of the prothrombin C20209T variant by differential sensitivity to restriction endonuclease digestion. J. Thromb. Haemost. 1: 2683-5, 2003.
|
