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J. Eric Russell, M.D.

Associate Professor of Medicine
Member, Credentials Committee, University of Pennsylvania Health Systems
Department: Medicine

Contact information
Biomedical Research Building, Room 808
421 Curie Boulevard
Philadelphia, PA 19104
Office: 215-898-4406
Fax: 215-573-7039
Graduate Group Affiliations
Education:
A.B. (Chemistry: magna cum laude)
Harvard University Cambridge, MA, 1980.
M.D. (Medicine)
Stanford University School of Medicine Palo Alto, CA , 1984.
Post-Graduate Training
Intern, Internal Medicine, Hospital of the University of Pennsylvania, 1984-1985.
Resident, Internal Medicine, Hospital of the University of Pennsylvania, 1985-1987.
Fellow, Hematology-Oncology, Hospital of the University of Pennsylvania, 1987-1991.
Associate, Howard Hughes Medical Institute, University of Pennsylvania School of Medicine, 1989-1991.
Research Associate, University of Pennsylvania School of Medicine, Medicine Hematology-Oncology, 1991-1996.
Research Associate, University of Pennsylvania School of Medicine, Department of Genetics, 1995-1996.
Certifications
Board Certification in Internal Medicine, 1987.
Board Certification in Medical Oncology, 1989.
Board Eligible in Hematology, 1989.
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Description of Research Expertise

RESEARCH INTERESTS

Control and function of human embryonic globin genes.

Key words: Globin, embryonic, sickle cell anemia, thalassemia, mRNA, prothrombin.

Description of Clinical Expertise

Hemoglobinopathies, thalassemias, sickle cell disease

Selected Publications

Jiang, Y., Xu, X.-S., and Russell, J.E.: The high stability of [beta]-globin mRNA requires site-specific binding of factors that remodel the structure of its 3'UTR. The 8th Cooley's Anemia Symposium, New York Academy of Sciences, March 17-19 2005.

Jiang, Y., Xu, X.-S., and Russell, J.E.: The high stability of human [beta]-globin mRNA is determined by a specific cis-element within its 3'UTR. 28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati, April 9-13 2005.

He, Z., and Russell, J.E.: Evidence that differential stabilization of [beta]-like globin mRNAs is mediated by specific determinants in their 3'UTRs. 28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati, April 9-13 2005.

Russell, J.E.: Adaptive post-transcriptional processes mitigate globin chain imbalance in [beta]-thalassemic erythrocytes. 27th Annual Meeting of the National Sickle Cell Disease Program, Los Angeles, April 18-21 2004 Notes: Oral presentation.

He, Z., and Russell, J.E.: Co-expression of human [zeta] globin corrects the sickle phenotype in mouse models of sickle cell disease. 27th Annual Meeting of the National Sickle Cell Disease Program, Los Angeles, April 18-21 2004 Notes: Oral presentation.

Frehm, E.J., Russell, J.E., and Gow, A.J.: Genetic and pharmacologic modulation of nitric oxide-hemoglobin reactivity. Eastern Society for Pediatric Research, Old Greenwich CT, March 26-28 2004 Notes: Oral presentation.

Russell, J.E.: Hemoglobinopathies and thalassemias. Medical Knowledge Self-Assessment Program 13. P.E. Epstein (eds.). Page: 30-32, 2003.

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Last updated: 07/18/2016
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