Karam C. Mounzer - Faculty Biosketch

Karam C. Mounzer, MD

Clinical Professor of Medicine (Infectious Diseases)

Attending Physician, Penn Presbyterian Medical Center

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Department: Medicine

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46 Contact information
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Philadelphia Fight
35 1233 Locust Street
Philadelphia, PA 19107

2e Office: 215-790-1788
32 Fax: 215-732-5490
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Email:
mounzerk@fight.org

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Links
59 AIDS service organization
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13 Education:
21 d Bachelor 38 (Experimental Sciences and French Literature) c
47 College Notre Dame de Jamhour, Beirut, Lebanon, 1985.
21 7 MD 23 (Pre-Med & Med combined) c
57 Saint Joseph University, Faculty of Medicine, Beirut, Lebanon , 1992.
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1f Post-Graduate Training
24 87 Internal Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 1992-1993.
24 66 Residency, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School 1b , 1993-1995.
24 7b Infectious Diseases Fellowship, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School 1b , 1995-1997.
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17 Certifications
28 34 Diplomate, American Board of Internal Medicine 16 , 1995.
28 35 Diplomate, American Board of Infectious Diseases 16 , 1997.
28 2f ABIM Internal Medicine, 2015.
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3 8b Permanent link
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b6 > Perelman School of Medicine > Faculty > Details a

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Description of Research Expertise

41 Clinical Development of new antiretroviral agents
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Description of Clinical Expertise

51 Treatment of Multi drug Resistant HIV virus, HIV-HCV co-infection
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Description of Other Expertise

49 Suboxone Clinic for HIV infected opioid-addicted patients
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Selected Publications

180 Maguire C, Rueve K, Farmer E, Huesgen E, Karaj A, Binkley A, Mounzer K, Brizzi M, Chary P, Sung P, Graziani A, Hiserodt E, Baron J, Koenig H, Short WR: Real World Virologic Outcomes in Patients With Elevated Body Mass Index Receiving Long Acting Cabotegravir/Rilpivirine. Clin Infect Dis 81(1): 67-74, Aug 2025.

1b9 McMyn NF, Varriale J, Wu HWS, Hariharan V, Moskovljevic M, Tan TS, Lai J, Singhal A, Lynn K, Mounzer K, Tebas P, Montaner LJ, Hoh R, Yu XG, Lichterfeld M, Simonetti FR, Kovacs C, Deeks SG, Siliciano JM, Siliciano RF: Factors associated with resistance of HIV-1 reservoir viruses to neutralization by autologous IgG antibodies. J Clin Invest 135(19): e194081, Jul 2025.

17c Mounzer K, Osterman MD, Brunet L, Hsu RK, Pierone G Jr, Fusco JS, Prata Menezes N, Gruber J, Lim T, Dunbar M, Fusco GP: Characterizing treatment interruptions in the OPERA cohort and virologic outcomes after resumption with bictegravir/emtricitabine/tenofovir alafenamide. AIDS Res Ther 22(1): 77, Jul 2025.

19c Pozniak A, Orkin C, Yazdanpanah Y, Baumgarten A, Mounzer K, D'Antoni ML, Huang H, Liu H, Andreatta K, VanderVeen LA, Callebaut C, Hindman JT, Arribas JR: Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) After A Viremic Event: A Pooled Analysis of Studies in People with HIV. Infect Dis Ther 14(6): 1201-1217, JUN 2025.

11b Mounzer K, Brunet L, Sension M, Hsu RK, Osterman MD, Fusco JS, Whiteside YO, Fusco GP: Weight loss with real-world doravirine use in the OPERA cohort: a US-based cohort study. AIDS Res Ther 22(1): 64, JUN 2025.

138 Mohammed Zogheib, John Koethe, Jordan E. Lake, Karam Mounzer, Christian Caldji, Brandon Cash, Colleen McGary: BMI Is a Poor Surrogate for Excess Visceral Adiposity and Cardiovascular Risk in Persons With HIV. CROI 2025 5(1): 239, May 2025.

1cc Richard K, Yuan Z, Tang H-Y, Goldman AR, Kuthu R, Raphane B, Register ET, Sharma P, Ross BN, Morris J, Williams DE, Cheney C, Wu G, Mounzer K, Laird GM, Zuck P, Andersen RJ, Simonambango S, Andrae-Marobela K, Tietjen I, Montaner LJ: Ex vivo and in vivo HIV-1 latency reversal by "Mukungulu," a protein kinase C-activating African medicinal plant extract. mBio. 16(5): e0381624, May 2025.

162 Karam Mounzer,Laurence Brunet, Ricky K. Hsu, Philip C. Lackey, Michael Sension, Michael B. Wohlfeiler, Joshua Gruber, Megan S. Dunbar, Seojin Park, Jennifer S. Fusco, Gregory P. Fusco: First Year of Lenacapavir Long-Acting Injectable Use in the OPERA Cohort. CROI 3(1): 123, 2025.

19d Natalie F. McMyn, Joseph Varriale, Hanna Wu, Vivek Hariharan, Jun Lai, Anushka Singhal, Kenneth Lynn, Karam Mounzer, Pablo Tebas, Luis J. Montaner, Colin M. Kovacs, Rebecca Hoh, Steven G. Deeks, Janet M. Siliciano, Robert F. Siliciano: Resistance of Inducible, Infectious HIV-1 to Autologous Neutralizing IgG After Long-Term ART. CROI 2025.

1ba Malcolm Hedgcock, pedro.cahn, Mounzer, Karam, Peter Sklar, Mauricio Montezuma , Nicolas Margot , Xu Zhang , Chloe Orkin : Demographic and clinical characteristics of Phase 3 participants in ARTISTRY-1, an open-label study comparing a bictegravir/lenacapavir (BIC/LEN) single tablet regimen (STR) with complex antiretroviral therapy (ART) regimens. EACS 1(1): 120, 2025.

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26 Last updated: 10/28/2025
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