Faculty | Infectious Diseases Division

Jay R. Kostman, M.D.

Clinical Professor of Medicine

Health System Clinician, University of Pennsylvania School of Medicine

Associate Director, Viral Hepatitis Center Perelman School of Medicine

Department: Medicine

Contact information

3910 Powelton Avenue
PPMC
Philadelphia, PA 19104

Office: 215-662-8693
Fax: 215-243-4658

Email:
kostman@mail.med.upenn.edu

Education:
B.A. (Chemistry)
Cornell University, 1980.
MD
Yale University, 1984.

Post-Graduate Training
Resident in Medicine, Temple University Hospital, Philadelphia, PA, 1984-1987.
Chief Resident in Medicine, Temple University Hospital, Philadelphia, PA , 1987-1988.
Fellow in Infectious Diseases, Temple University Hospital, Philadelphia, PA , 1988-1991.

Certifications
American Board of Internal Medicine, 1987.
Subspecialty of Infectious Diseases, 2008.

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Papasavvas, Emmanouil. Chehimi, Jihed. Azzoni, Livio. Pistilli, Maxwell. Thiel, Brian. Mackiewicz, Agnieszka. Creer, Shenoa. Mounzer, Karam. Kostman, Jay R. Montaner, Luis J.: Retention of functional DC-NK cross-talk following up to 18 weeks therapy interruptions in chronically suppressed HIV type 1+ subjects. AIDS Research & Human Retroviruses 26(10): 1047-9, Oct 2010.

Raymond, Andrea D. Gekonge, Bethsebah. Giri, Malavika S. Hancock, Aidan. Papasavvas, Emmanouil. Chehimi, Jihed. Kossenkov, Andrew V. Nicols, Calen. Yousef, Malik. Mounzer, Karam. Shull, Jane. Kostman, Jay. Showe, Louise. Montaner, Luis J.: Increased metallothionein gene expression, zinc, and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia.[Erratum appears in J Leukoc Biol. 2010 Nov;88(5):1061 Note: Kossevkov, Andrew V [corrected to Kossenkov, Andrew V]] Journal of Leukocyte Biology 88(3): 589-96, Sep 2010.

Goetz, Matthew Bidwell. Leduc, Robert. Wyman, Nicole. Kostman, Jay R. Labriola, Ann M. Lie, Yolanda. Weidler, Jodi. Coakley, Eoin. Bates, Michael. Luskin-Hawk, Roberta. Long Term Monitoring Study (CPCRA060) Terry Beirn Community Programs for Clinical Research on AIDS.: HIV replication capacity is an independent predictor of disease progression in persons with untreated chronic HIV infection. Journal of Acquired Immune Deficiency Syndromes: JAIDS 53(4): 472-9, Apr 1 2010.

Chehimi, Jihed. Papasavvas, Emmanouil. Tomescu, Costin. Gekonge, Bethsebah. Abdulhaqq, Shaheed. Raymond, Andrea. Hancock, Aidan. Vinekar, Kavita. Carty, Craig. Reynolds, Griffin. Pistilli, Maxwell. Mounzer, Karam. Kostman, Jay. Montaner, Luis J.: Inability of plasmacytoid dendritic cells to directly lyse HIV-infected autologous CD4+ T cells despite induction of tumor necrosis factor-related apoptosis-inducing ligand. Journal of Virology 84(6): 2762-73, Mar 2010.

DallaPiazza, Michelle. Amorosa, Valerianna K. Localio, Russell. Kostman, Jay R. Lo Re, Vincent 3rd.: Prevalence and risk factors for significant liver fibrosis among HIV-monoinfected patients. BMC Infectious Diseases 10: 116, 2010.

Amorosa, Valerianna K. Slim, Jihad. Mounzer, Karam. Bruno, Christopher. Hoffman-Terry, Margaret. Dorey-Stein, Zachariah. Ferrara, Thomas. Kostman, Jay R. Lo Re, Vincent 3rd.: The influence of abacavir and other antiretroviral agents on virological response to HCV therapy among antiretroviral-treated HIV-infected patients. Antiviral Therapy 15(1): 91-9, 2010.

Lo Re, Vincent 3rd. Guaraldi, Giovanni. Leonard, Mary B. Localio, Anthony R. Lin, Jennifer. Orlando, Gabriella. Zirilli, Lucia. Rochira, Vincenzo. Kostman, Jay R. Tebas, Pablo.: Viral hepatitis is associated with reduced bone mineral density in HIV-infected women but not men. AIDS 23(16): 2191-8, Oct 23 2009.

Giri, Malavika S. Nebozyhn, Michael. Raymond, Andrea. Gekonge, Bethsebah. Hancock, Aidan. Creer, Shenoa. Nicols, Calen. Yousef, Malik. Foulkes, Andrea S. Mounzer, Karam. Shull, Jane. Silvestri, Guido. Kostman, Jay. Collman, Ronald G. Showe, Louise. Montaner, Luis J.: Circulating monocytes in HIV-1-infected viremic subjects exhibit an antiapoptosis gene signature and virus- and host-mediated apoptosis resistance. Journal of Immunology 182(7): 4459-70, Apr 1 2009.

Papasavvas, Emmanouil. Foulkes, Andrea. Li, Xiaohong. Kostman, Jay R. Mounzer, Karam C. Montaner, Luis J.: Evidence of a decrease in CD4 recovery once back on antiretroviral therapy after sequential > or =6 weeks antiretroviral therapy interruptions. Journal of Acquired Immune Deficiency Syndromes: JAIDS 50(3): 334-5, Mar 1 2009.

Goetz, Matthew Bidwell. Leduc, Robert. Kostman, Jay R. Labriola, Ann M. Lie, Yolanda. Weidler, Jodi. Coakley, Eoin. Bates, Michael. Luskin-Hawk, Roberta. Long-Term Monitoring Study (CPCRA 060) and Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA).: Relationship between HIV coreceptor tropism and disease progression in persons with untreated chronic HIV infection. Journal of Acquired Immune Deficiency Syndromes: JAIDS 50(3): 259-66, Mar 1 2009.