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Keith William Hamilton, MD

Professor of Clinical Medicine (Infectious Diseases)
Attending Physician, Hospital of the University of Pennsylvania, Infectious Diseases Division
Director Internal Medicine Clerkship, Perelman School of Medicine, University of Pennsylvania
Associate Hospital Epidemiologist, Hospital of the University of Pennsylvania
Director of Undergraduate Medical Education, Department of Medicine, Perelman School of Medicine
Director of Curriculum Design for Vin University Medical School in Hanoi, Vietnam, Center for Global Health at the University of Pennsylvania
Director of Innovation and Technology for Antimicrobial Stewardship, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
Department of Medicine, 100 Centrex Building
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-6932
Education:
BA (Major in Chemistry, Minor in American Government)
Franklin and Marshall College, 2002.
MD (Medicine)
University of Pennsylvania School of Medicine, 2006.
Post-Graduate Training
Internal Medicine, Hospital of the University of Pennsylvania, 2006-2007.
Internal Medicine, Hospital of the University of Pennsylvania, 2007-2009.
Infectious Diseases, Hospital of the University of Pennsylvania, 2009-2011.
Basic Training Course in Healthcare Epidemiology, The Society for Healthcare Epidemiology of America/Centers for Disease Control, 2011-2011.
Principles of Medical Education: Maximizing Your Teaching Skills, Harvard Medical School, 2011-2011.
Course for New Clerkship Directors, Clerkship Directors in Internal Medicine, 2011-2011.
Advanced Training Course in Healthcare Epidemiology, The Society for Healthcare Epidemiology of America/Centers for Disease Control , 2012-2012.
Penn Medicine Physician Leadership Academy, University of Pennsylvania Health System, 2013-2014.
Penn Medicine Leadership Enhancement 2.0, Penn Medicine, 2020-2020.
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Description of Clinical Expertise

Treatment of Non-tuberculous Mycobacterial Infections
Healthcare Epidemiology
Antimicrobial Stewardship
General Infectious Diseases

Description of Other Expertise

Undergraduate Medical Education

Description of Research Expertise

Healthcare Epidemiology
Antimicrobial Stewardship
Non-tuberculous Mycobacterial Infections
Undergraduate Medical Education

Selected Publications

Patel, VM, Chu B, Hamilton KW, Bellamy C, Harker C, Bryer JS, Shields B, Hirsh RL, Fadugba OO, Micheletti RG.: Penicillin allergy evaluation in hospitalized patients with hematologic malignancy. Antimicrob Steward Healthc Epidemiol. 2023 Notes: In press.

Serletti L, Dutcher L, Degnan KO, Szymczak JE, Cluzet V, David MZ, Cressman L, Glassman LW, Hamilton KW.: Analysis of seasonal variation of antibiotic prescribing for respiratory tract diagnoses in primary care practices. Antimicrob Steward Healthc Epidemiol. 2023 Notes: In press.

Millstein JH, Asch DA, Hamilton K, Adusumali S, Kaskebar N, Ahya V, Al-Ramahi N: Decision support and centralized pharmacy consultation for nirmatrelvir-ritonavir prescribing in an academic health system—a model to promote drug access and reduce provider burden. J Gen Intern Med November 2022.

Zhang HL, Anesi JA, Hamilton KW, Cressman L, Bilker WB, Lautenbach E: The impact of reported beta-lactam allergy on clinical outcomes and antibiotic use among solid organ transplant recipients. Open Forum Infect Dis 9(8): ofac384, July 2022.

Lautenbach E, Hamilton KW, Grudmeier R, Neuhauser MM, Hicks LA, Jaskowiak-Barr A, Cressman L, James T, Omorogbe J, Frager N, Menon M, Kratz E, Dutcher L, Chiotos K, Gerber JS: Development of an electronic algorithm to target outpatient antimicrobial stewardship efforts for acute bronchitis and pharyngitis. Open Forum Infect Dis 9(7): ofac273, June 2022.

Dutcher L, Li Y, Lee G, Grundmeier R, Hamilton KW, Gerber JS: The impact of the COVID-19 pandemic on antibiotic prescribing in pediatric primary care. Pediatrics 149(2): e2021053079, February 2022.

Yarrington ME, Moehring RW, David MZ, Hamilton KW, Klompas M, Rhee C, Hsueh K, Dodds Ashly E, Sinkowitz-Cochran RL, Ryan M, Anderson DJ: A modified Delphi approach to develop a trial protocol for antibiotic de-escalation in patients with suspected sepsis. Antimicrob Steward Healthc Epidemiol 1(1): e44, November 2021.

Dutcher L, Degnan K, Adu-Gyamfi AB, Lautenbach E, Cressman L, David MZ, Cluzet V, Szymczak JE, Pegues DA, Bilker W, Tolomeo P, Hamilton KW.: Improving Outpatient Antibiotic Prescribing for Respiratory Tract Infections in Primary Care; a Stepped-Wedge Cluster Randomized Trial. Clin Infect Dis. 1(1): ciab602, July 2021 Notes: https://doi.org/10.1093/cid/ciab602.

Degnan KO, Cluzet V, David MZ, Dutcher L, Cressman L, Lautenbach E, Hamilton KW.: Development and validation of antibiotic stewardship metrics for outpatient respiratory tract diagnoses and association of provider characteristics with inappropriate prescribing. Infect Control Hosp Epidemiol. 2(1): 1-8, June 2021.

Wang R, Degnan KO, Luther VP, Szymczak JE, Goren EN, Logan A, Shnekendorf R, Hamilton KW.: Development of multifaceted antimicrobial stewardship curriculum for undergraduate medical education: the ASSURE elective. Open Forum Infect Dis. 8(6), May 2021 Notes: https://doi.org/10.1093/ofid/ofab231.

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Last updated: 10/09/2023
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