Faculty | Infectious Diseases Division

David A Pegues, MD

Professor of Medicine at the Hospital of the University of Pennsylvania

Medical Director, Antimicrobial Management Program, Hospital of the University of Pennsylvania

Medical Director, Healthcare Epidemiology and Infection Control, Hospital of the University of Pennsylvania

Department: Medicine

Contact information

University of Pennsylvania Medical Center
Penn Tower Lobby, Suite 101
399 South 34th St.
Philadelphia, PA 19104-4283

Office: 215-614-1614
Fax: 215-662-7971

Education:
BA (Biology)
University of Chicago, 1982.
MD
University of Chicago Pritzker School of Medicine, 1986.

Post-Graduate Training
Resident in Internal Medicine, Temple University Hospital, Philadelphia, PA, 1986-1989.
Epidemic Intelligence Service Officer, Epidemiology Branch, Hospital Infections Program, Centers for Disease Control and Prevention, Atlanta, GA, 1989-1991.
Resident in Preventive Medicine, CDC Atlanta, GA, 1990-1992.
Resident, Division of Epidemiology, Alabama Department of Public Health, Montgomery, AL, 1991-1992.
Clinical Fellow in Medicine, Massachusetts General Hospital (MGH), Infectious Disease Unit, Boston, MA, 1992-1993.
Infectious Disease Fellow, MGH, Laboratory of Samuel I. Miller, MD, 1993-1995.
Clinical and Research Fellow in Medicine, Massachusetts General Hospital (MGH), Infectious Disease Unit, Boston, MA, 1993-1996.
Infectious Disease Fellow, MGH, Laboratory of David C. Hooper, MD, 1995-1996.

Certifications
Diplomat, ABIM, Internal Medicine, 1989.
Diplomat, ABIM, Infectious Disease, 1996.
Recertification, ABIM, Infectious Disease, 2006.

Permanent link

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Description of Research Expertise

Dr. Pegues research interests include the epidemiology of vancomycin resistant and daptomycin non-susceptible enterococci; prevention and treatment of opportunistic infections in organ transplant recipients; device-associated infections; novel infection control technologies to reduce environmental microbial contamination and infection risk; and the epidemiology of Burkholderia cepacia complex in persons with cystic fibrosis.

Selected Publications

Kelisides T, Humphries R, Uslan DZ, Pegues DA : De novo daptomycin-nonsusceptible enterococcal infections. Emerg Infect Dis 18(4): 674-6. 2012.

T Kelesidis, Chow ALP, Humphries R, Uslan DZ, Pegues DA: Case-control study comparing de novo and daptomycin-exposed daptomycin-nonsusceptible Enterococcus infections. Antimicrob Agents Chemother 56(4): 2150-2, 2012.

Pegues DA: Commentary on Drekonja, DM et al (2011) Comparative effectiveness of Clostridium difficile treatments: a systematic review. ACP Journal Club (156:), JC4-9, 2012.

Kelesidis T, Humphries R, Terashita D, Eshaghian S, Territo MC, Said J, Lewinski M, Currier JS, Pegues D: Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Los Angeles County. J Med Virology 84(5): 777-85, 2012.

Kelesidis T, Humphries R, Pegues D : Case series of daptomycin nonsusceptible Enterococcus infections with no prior daptomycin exposure in a tertiary center. IDSA 49th Annual Meeting. Boston, MA October 20-23 2011 Notes: Poster Presentation.

Kelesidis T, Humphries R, Pegues D: Daptomycin nonsusceptible Enterococcus infections can develop in the absence of prior antimicrobial exposure. IDSA 49th Annual Meeting. Boston, MA October 20-23 2011 Notes: Poster Presentation.

Humphries RM, Saeki S, Kwan N, Kato E, Lewinski M, Pegues DA: Prevalence of vancomycin resistant enterococcus in patients with suspect C. difficile infection: a 10-year experience. 51st ICAAC, Chicago, IL, September 17-20 2011 Notes: Poster presentation.

Kelesidis T, Uslan D, Pegues D: Case Series of daptomycin non-susceptible enterococcus infections in a tertiary center. SHEA 20th Annual Meeting, Dallas, TX, April 1-4 2011 Notes: Poster Presentation.

O'Grady NP, Alexander M, Burns LA, Dellinger P, Garland J. Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML, Raad II, Randolph A, Rupp ME, Saint S and the Healthcare Infection Control Practices Advisory Committee : 2011 Guidelines for the Prevention of Intravascular Catheter-Related Infections. Am J Infect Control 39(Suppl 1): S1-34, 2011.

MacCannell T, Umscheid CA, Agarwal RK, Lee I, Kuntz G, Stevenson KB and the Healthcare Infection Control Practices Advisory Committee : Guideline for the Prevention and Control of Norovirus Gastroenteritis Outbreaks in Healthcare Settings. Infect Control Hosp Epidemiol 32: 939-69, 2011.