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David A Pegues, MD

Professor of Medicine at the Hospital of the University of Pennsylvania
Medical Co-Director, Antimicrobial Management Program, Hospital of the University of Pennsylvania
Medical Director, Healthcare Epidemiology and Infection Control, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
University of Pennsylvania Medical Center
Penn Tower Lobby, Suite 101
399 South 34th St.
Philadelphia, PA 19104-4283
Office: 215-614-1614
Fax: 215-662-7971
BA (Biology)
University of Chicago, 1982.
University of Chicago Pritzker School of Medicine, 1986.
Post-Graduate Training
Resident in Internal Medicine, Temple University Hospital, Philadelphia, PA, 1986-1989.
Epidemic Intelligence Service Officer, Epidemiology Branch, Hospital Infections Program, Centers for Disease Control and Prevention, Atlanta, GA, 1989-1991.
Resident in Preventive Medicine, CDC Atlanta, GA, 1990-1992.
Resident, Division of Epidemiology, Alabama Department of Public Health, Montgomery, AL, 1991-1992.
Clinical Fellow in Medicine, Massachusetts General Hospital (MGH), Infectious Disease Unit, Boston, MA, 1992-1993.
Clinical and Research Fellow in Medicine, Massachusetts General Hospital (MGH), Infectious Disease Unit, Boston, MA, 1993-1996.
Infectious Disease Fellow, MGH, Laboratory of Samuel I. Miller, MD, 1993-1995.
Infectious Disease Fellow, MGH, Laboratory of David C. Hooper, MD, 1995-1996.
Diplomat, ABIM, Internal Medicine, 1989.
Diplomat, ABIM, Infectious Disease, 1996.
Recertification, ABIM, Infectious Disease, 2006.
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Description of Clinical Expertise

Transplant infectious diseases, healthcare-associated infections including catheter-associated urinary tract infections, Salmonellosis

Description of Research Expertise

Dr. Pegues research interests include the epidemiology of vancomycin resistant and daptomycin non-susceptible enterococci; prevention and treatment of opportunistic infections in organ transplant recipients; device-associated infections; novel infection control technologies to reduce environmental microbial contamination and infection risk; and the epidemiology of Burkholderia cepacia complex in persons with cystic fibrosis.

Selected Publications

McMullen SE, Pegues DA, Shofer FA, Sheller AC,Wiener EB. : Performance of QuantiFERON-TB Gold in-tube and tuberculin skin test in a U.S. college student population relative to risk of exposure to tuberculosis. Clin Infect Dis 58: 1206-6, 2014.

Mortensen E, Hellinger W, Ahmedov S, Salfinger M, Keller C, Cowan, LS, Ashkin D, Calvet H, Shaw T, Hwang S, Pegues, D, Bower WA : Donor-derived pulmonary tuberculosis in lung transplant recipients: opportunities for early diagnosis and prevention of infection. Transplant Infect Dis 16: 27-75, 2014.

McMullen SE, Pegues DA, ShoferFS, Sheller AC: Responses to Islam, Grinsdale, Bristow and Higashi, and to Mendy, Albatineh, Vieira, and Gasana Clin Infect Dis 59: e published ahead of print, 2014.

Caroff DA, Edelstein PH, Hamilton K, Pegues DA for the CDC Prevention Epicenter Program: The Bristol stool form scale and its relationship to Clostridium difficile infection J Clin Microbiol 52: 3437-9, 2014.

Low E, Nicolle L, Coffin SE, Gould C, Maragakis, L, Meddings J, Pegues DA, Pettis AM, Saint S, Yokoe DS. : Strategies to prevent catheter-associated urinary tract infections in acute care hospitals. Infect Control Hosp Epidemiol 35: 464-79, 2014.

Pegues DA: Translating and scaling the HHS Action Plan to prevent healthcare-associated infections to the local level: experience of a Los Angeles Health System. Medical Care 52(2 Suppl 1): S60-5, 2013.

Tehran DS, Russell D, Brown J, Boynton-Delahanty K, Quan K, Gibbs L, Braddock G, Zaroda T, Koopman M, Thompson D, Nichols A, Cui E, Liu C, Cohen, Rubin Z, Pegues D, Torriani F, Datta R, Huang SS. : Discord among performance measures for central line associated bloodstream infections. Infect Control Hosp Epidemiol 34: 176-83, 2013.

Kelisides T, Humphries R, Uslan DZ, Pegues DA : De novo daptomycin-nonsusceptible enterococcal infections. Emerg Infect Dis 18(4): 674-6. 2012.

T Kelesidis, Chow ALP, Humphries R, Uslan DZ, Pegues DA: Case-control study comparing de novo and daptomycin-exposed daptomycin-nonsusceptible Enterococcus infections. Antimicrob Agents Chemother 56(4): 2150-2, 2012.

Kelesidis T, Humphries R, Terashita D, Eshaghian S, Territo MC, Said J, Lewinski M, Currier JS, Pegues D: Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Los Angeles County. J Med Virology 84(5): 777-85, 2012.

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Last updated: 03/23/2015
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