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David A Pegues, MD

Professor of Medicine at the Hospital of the University of Pennsylvania
Medical Director, Antimicrobial Management Program, Hospital of the University of Pennsylvania
Medical Director, Healthcare Epidemiology and Infection Control, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
University of Pennsylvania Medical Center
Penn Tower Lobby, Suite 101
399 South 34th St.
Philadelphia, PA 19104-4283
Office: 215-614-1614
Fax: 215-662-7971
BA (Biology)
University of Chicago, 1982.
University of Chicago Pritzker School of Medicine, 1986.
Post-Graduate Training
Resident in Internal Medicine, Temple University Hospital, Philadelphia, PA, 1986-1989.
Epidemic Intelligence Service Officer, Epidemiology Branch, Hospital Infections Program, Centers for Disease Control and Prevention, Atlanta, GA, 1989-1991.
Resident in Preventive Medicine, CDC Atlanta, GA, 1990-1992.
Resident, Division of Epidemiology, Alabama Department of Public Health, Montgomery, AL, 1991-1992.
Clinical Fellow in Medicine, Massachusetts General Hospital (MGH), Infectious Disease Unit, Boston, MA, 1992-1993.
Clinical and Research Fellow in Medicine, Massachusetts General Hospital (MGH), Infectious Disease Unit, Boston, MA, 1993-1996.
Infectious Disease Fellow, MGH, Laboratory of Samuel I. Miller, MD, 1993-1995.
Infectious Disease Fellow, MGH, Laboratory of David C. Hooper, MD, 1995-1996.
Diplomat, ABIM, Internal Medicine, 1989.
Diplomat, ABIM, Infectious Disease, 1996.
Recertification, ABIM, Infectious Disease, 2006.
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Description of Clinical Expertise

Transplant infectious diseases, healthcare-associated infections including catheter-associated urinary tract infections, Salmonellosis

Description of Research Expertise

Dr. Pegues research interests include the epidemiology of vancomycin resistant and daptomycin non-susceptible enterococci; prevention and treatment of opportunistic infections in organ transplant recipients; device-associated infections; novel infection control technologies to reduce environmental microbial contamination and infection risk; and the epidemiology of Burkholderia cepacia complex in persons with cystic fibrosis.

Selected Publications

Tehran DS, Russell D, Brown J, Boynton-Delahanty K, Quan K, Gibbs L, Braddock G, Zaroda T, Koopman M, Thompson D, Nichols A, Cui E, Liu C, Cohen, Rubin Z, Pegues D, Torriani F, Datta R, Huang SS. : Discord among performance measures for central line associated bloodstream infections. Infect Control Hosp Epidemiol 34: 176-83, 2013.

Kelisides T, Humphries R, Uslan DZ, Pegues DA : De novo daptomycin-nonsusceptible enterococcal infections. Emerg Infect Dis 18(4): 674-6. 2012.

Riley M, Suda M, Tabsh K, Flood A, Pegues DA : Reduction of surgical site infections in low transverse cesarean section at a university hospital. Am J Infect Control 40: 820-5, 2012.

T Kelesidis, Chow ALP, Humphries R, Uslan DZ, Pegues DA: Case-control study comparing de novo and daptomycin-exposed daptomycin-nonsusceptible Enterococcus infections. Antimicrob Agents Chemother 56(4): 2150-2, 2012.

Kelesidis T, Humphries R, Terashita D, Eshaghian S, Territo MC, Said J, Lewinski M, Currier JS, Pegues D: Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Los Angeles County. J Med Virology 84(5): 777-85, 2012.

Kelisides T, Humphries R, Uslan DZ, Pegues DA: Daptomycin nonsusceptible enterococci: an emerging challenge for clinicians. Clin Infect Dis 52(2): 228-34, 2011.

Gould DV, Umscheid CA, Agarwal RK, Kuntz G, Pegues DA and the Healthcare and Infection Control Practices Advisory Committee: Guideline for prevention of catheter-associated urinary tract infections 2009. Infect Control Hosp Epidemiol 31: 319-326, 2010.

Brahn E, Pegues DA, Yao Q, Craft N: Mucocutaneous leishmaniasis presenting as Wegener's granulomatosis. J Clin Rheumatol 16: 125-8, 2010.

Kubak BM, Gregson AL, Pegues DA, Leibowitz MR, Carlson M, Marelli D, Patel J, Laks H, Kobashigawa JA: Use of hearts transplanted from donors with severe sepsis and infectious deaths. J Heart Lung Transpl 28(3): 260-5, Mar 2009.

Gorgulho A, Juillard C, Uslan D, Tajik K, Aurasteh P, Behnke E, Pegues DA, De Salles AAF.: Risk factors for infection in deep brain stimulator surgery performed in the conventional and MRI operating room. J Neurosurg 110: 239-46, 2009.

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Last updated: 03/25/2014
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