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David A Pegues, MD

Professor of Medicine at the Hospital of the University of Pennsylvania
Medical Co-Director, Antimicrobial Management Program, Hospital of the University of Pennsylvania
Medical Director, Healthcare Epidemiology and Infection Control, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Ground Founders, Hospital of the University of Pennsylvania
Philadelphia, PA 19104-4283
Office: 215-614-1614
Fax: 215-662-7971
BA (Biology)
University of Chicago, 1982.
University of Chicago Pritzker School of Medicine, 1986.
Post-Graduate Training
Resident in Internal Medicine, Temple University Hospital, Philadelphia, PA, 1986-1989.
Epidemic Intelligence Service Officer, Epidemiology Branch, Hospital Infections Program, Centers for Disease Control and Prevention, Atlanta, GA, 1989-1991.
Resident in Preventive Medicine, CDC Atlanta, GA, 1990-1992.
Resident in Preventive Medicine, Division of Epidemiology, Alabama Department of Public Health, Montgomery, AL, 1991-1992.
Clinical Fellow in Medicine, Massachusetts General Hospital (MGH), Infectious Disease Unit, Boston, MA, 1992-1993.
Infectious Disease Fellow, MGH, Laboratory of Samuel I. Miller, MD, 1993-1995.
Clinical and Research Fellow in Medicine, Massachusetts General Hospital (MGH), Infectious Disease Unit, Boston, MA, 1993-1996.
Infectious Disease Fellow, MGH, Laboratory of David C. Hooper, MD, 1995-1996.
Diplomat, ABIM, Internal Medicine, 1989.
Diplomat, ABIM, Infectious Disease, 1996.
Recertification, ABIM, Infectious Disease, 2006.
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Description of Clinical Expertise

Transplant infectious diseases, healthcare-associated infections including catheter-associated urinary tract infections, Salmonellosis

Description of Research Expertise

Dr. Pegues research interests include the epidemiology of vancomycin resistant and daptomycin non-susceptible enterococci; prevention and treatment of opportunistic infections in organ transplant recipients; device-associated infections; novel infection control technologies and strategies to reduce environmental microbial contamination and infection risk; and the epidemiology of Burkholderia cepacia complex in persons with cystic fibrosis.

Selected Publications

Dy S, Major-Joynes B, Pegues D, Bradway C: Development, implementation and evaluation of a nurse driven protocol for removiing indwelling urinary catheters across a multi-hospital academic healthcare system. Urol Nurs 2016.

Lukaszewicz Bushen J, Mehta JM, Lautenbach E, Hamilton K, Binkley S, Timko D, Morgan SC, Pegues DA: Impact of two different antimicrobial stewardship methods on frequency of streamlining antimicrobial agents in patients with bacteremia. Infect Control Hosp Epidemiol 2016.

See I, Chang J, Gualandi N, Buser G, Rohrbach P, Smeltz DA, Bellush MJ, Coffine SE, Gould JM, Hess D, Hennessey P, Hubbard S, Kiernan A, O’Donnell J, Pegues DA, Miller FR, Magill SS: Clinical correlates of surveillance events detected by National Healthcaqre Safety Network pneumonia and lower respiratory infection definitions. Infect Control Hosp Epidemiol 37: 1-7, 2016.

Pegues DA, Han J, Gilmar C. McDonnell B, Gaynes S: Impact of ultraviolet germicidal irradiation for terminal room disinfection on C. difficile infection incidence among liquid oncology patients. Infect Control Hosp Epidemiol 2016.

Suryaprasad A, Basavaraju S V, Hocevar S N, Theodoropoulos N, Zuckerman R A, Hayden T, Forbi J C, Pegues D, Levine M, Martin S I, Kuehnert M J, Blumberg E A: Transmission of Hepatitis C Virus From Organ Donors Despite Nucleic Acid Test Screening. Am J Transplant 15(7): 1827-35, Jul 2015.

Han JH, Sullivan N, Leas BF, Pegues DA, Kaczmarek JL, Umscheid CA. : Environmental cleaning for the prevention of healthcare-associated infections. AHRQ Comparative Effectiveness Technical Briefs AHRQ Publication No. 15-EHC020_E Aug.(15-EHC020-EF), 2015.

McMullen SE, Pegues DA, Shofer FA, Sheller AC,Wiener EB. : Performance of QuantiFERON-TB Gold in-tube and tuberculin skin test in a U.S. college student population relative to risk of exposure to tuberculosis. Clin Infect Dis 58: 1206-6, 2014.

McMullen SE, Pegues DA, ShoferFS, Sheller AC: Responses to Islam, Grinsdale, Bristow and Higashi, and to Mendy, Albatineh, Vieira, and Gasana Clin Infect Dis 59: e published ahead of print, 2014.

Caroff DA, Edelstein PH, Hamilton K, Pegues DA for the CDC Prevention Epicenter Program: The Bristol stool form scale and its relationship to Clostridium difficile infection J Clin Microbiol 52: 3437-9, 2014.

Low E, Nicolle L, Coffin SE, Gould C, Maragakis, L, Meddings J, Pegues DA, Pettis AM, Saint S, Yokoe DS: Strategies to prevent catheter-associated urinary tract infections in acute care hospitals. Infect Control Hosp Epidemiol 35: 464-79, 2014.

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Last updated: 09/08/2016
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