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Chris T Derk, MD, MS

Professor of Clinical Medicine (Rheumatology)
Department: Medicine

Contact information
Division of Rheumatology
3400 Spruce Street
5th Floor White Bldg
Philadelphia, PA 19104
Office: 215-662-2792
Fax: 215-662-4500
Education:
AA
Harrisburg Area Community College, 1988.
BS (Pre-Medicine)
Pennsylvania State University, 1990.
MD
Thomas Jefferson University, 1994.
MS (Pharmacology)
Thomas Jefferson University, 2006.
Post-Graduate Training
Intern, Medicine, Abington Memorial Hospital, Abington, PA, 1994-1995.
Resident, Medicine, Abington Memorial Hospital, Abington, PA, 1995-1997.
NIH Research Postdoctoral Fellow in Molecular Rheumatology and Orthopedic Research, Thomas Jefferson University, Philadelphia, PA, 2001-2003.
Fellow, Rheumatology, , Thomas Jefferson University, Philadelphia, PA, 2001-2003.
K30 Clinical Research Pharmacology MS degree, Thomas Jefferson College of Graduate Studies, Philadelphia, PA, 2002-2006.
Certifications
Rheumatology, 2003.
Rheumatology, 2013.
Rheumatology, 2023.
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Selected Publications

Mehmetoglu E, Mummadisetty A, Chatzitofis A, Parperis K, Sandorfi N, Derk CT: A systematic review of prevalence and predictors of depression in systemic sclerosis based on the CES-D, BDI and PHQ-9 self-assessment questionnaires. Clin Rheumatol April 2025.

Hajnoczky N, Levin LS, Sandorfi N, Derk CT: Long-term outcomes of vascular grafting of medium-sized vessels of wrist and hand in systemic sclerosis patients with medication refractory Raynaud's. J Scleroderma Relat Disord April 2025.

Parperis K, Papachristodoulou M, Derk C, Psarelis S, Voskarides K, Chatzittofis A. : Post-traumatic stress disorder and systemic lupus erythematosus: insights from a systematic review. Rheumatology April 2025.

Aguila T, Madan R, Palmer MB, Derk CT: Zebra bodies in kidney biopsy: Drug-induced phospholipidosis in patient with Systemic Lupus Erythematosus. J Rheumatol March 2025.

Papchristodoulou E; Kakkoulis L; Chopra R; Derk CT, Parperis K: Clinical Features and Treatment Outcomes in Aseptic Abscess Syndrome: A Systematic Review of 104 Cases. ACR Convergence 2025.

GRASP study group: Functional NOTCH4 Variants Drive Vasculopathy and Fibrosis in Systemic Sclerosis. ACR Convergence 2025.

Parperi K, Costi E, Philippou S, Hadi M, Derk CT: Efficacy of disease modifying antirheumatic drugs in the treatment of granulomatous mastitis: a systematic review. Rheumatol Int 44(11): 2371-79, Nov 2024.

GRASP study group: Rare variants in the IL1RAP gene implicate the IL-1 signaling pathway in the pathogenesis of systemic sclerosis in African and European ancestries. ACR annual scientific meeting, Washington DC 2024.

GRASP study group: Admixture mapping and gene-based analysis identifies rare variants in genes in the IL-13 and TGF beta signaling pathways in African Americans with systemic sclerosis. ACR annual scientific meeting, Washington DC 2024.

GRASP study Group: TCR motifs identify unique clones in African Americans with systemic sclerosis ACR annual Scientific meeting, Washington DC 2024.

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Last updated: 08/04/2025
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