Selected Publications

Sokratis Apostolidis, Kyra Sacksith, Bria Fulmer, Zoe Quandt, Mark Anderson, Terri Laufer and E. John Wherry: Unique Cellular and Autoantibody Signatures in Patients with irAEs Revealed by Longitudinal Immune Tracking. ACR Convergence 2023, San Diego November 2023 Notes: Poster presentation.

Mark M Painter, Timothy S Johnston, Kendall A Lundgreen, Jefferson J S Santos, Juliana S Qin, Rishi R Goel, Sokratis A Apostolidis, Divij Mathew, Bria Fulmer, Justine C Williams, Michelle L McKeague, Ajinkya Pattekar, Ahmad Goode, Sean Nasta, Amy E Baxter, Josephine R Giles, Ashwin N Skelly, Laura E Felley, Maura McLaughlin, Joellen Weaver; Penn Medicine BioBank; Oliva Kuthuru, Jeanette Dougherty, Sharon Adamski, Sherea Long, Macy Kee, Cynthia Clendenin, Ricardo da Silva Antunes, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Alexander C Huang, Daniel J Rader, Scott E Hensley, Paul Bates, Allison R Greenplate, E John Wherry: Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection. Nat Immunol 24(10): 1711-1724, October 2023 Notes: doi: 10.1038/s41590-023-01613-y.

Sokratis Apostolidis, Kyra Sacksith, Bria Fulmer, Zoe Quandt, Mark Anderson, E. John Wherry, Terri Laufer: Unique Cellular and Autoantibody Signatures in Patients with irAEs Revealed by Longitudinal Immune Tracking. FOCIS 2023, Boston June 2023 Notes: Oral presentation.

Sokratis Apostolidis, Paulina Coutifaris, Mark Painter, Ajinkya Pattekar, Rishi Goel, Divij mathew, Wenzhao Meng, Kevin Wang, Bria Fulmer, Angela Corrigan, Kendall Lundgreen, Elizabeth Drapeau, Derek Oldridge, Josephine Giles, Amy Baxter, Sasikanth Manne, Michelle Mckeague, Ahron Flowers, Oliva Kuthuru, Sherea Long, Jeanette Dougherty, Sigrid Gouma, Justine Williams, Maura McLaughlin, Sharon Adamski, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Scott Hensley, Paul Bates, Eline Luning Prak, Laura Vella, Giorgos Karakousis, Ravi Amaravadi, Suzanne McGettigan, Kristin Kreider, Tara Mitchell, Allison Greenplate, Lynn Schuchter, Alexander Huang and E. John Wherry: Cellular and Humoral Responses Following SARS-CoV-2 mRNA Vaccination in Patients on PD-1 Immunotherapy with irAEs. ACR Convergence 2022, Philadelphia November 2022 Notes: Oral presentation.

Anderson EM, Li SH, Awofolaju M, Eilola T, Goodwin E, Bolton MJ, Gouma S, Manzoni TB, Hicks P, Goel RR, Painter MM, Apostolidis SA, Mathew D, Dunbar D, Fiore D, Brock A, Weaver J, Millar JS, DerOhannessian S, Greenplate AR, Frank I, Rader DJ, Wherry EJ, Bates P, Hensley SE: SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations. Cell Rep 41(3): 111496, October 2022 Notes: doi: 10.1016/j.celrep.2022.111496.

Herati RS, Knorr DA, Vella LA, Silva LV, Chilukuri L, Apostolidis SA, Huang AC, Muselman A, Manne S, Kuthuru O, Staupe RP, Adamski SA, Kannan S, Kurupati RK, Ertl HCJ, Wong JL, Bournazos S, McGettigan S, Schuchter LM, Kotecha RR, Funt SA, Voss MH, Motzer RJ, Lee CH, Bajorin DF, Mitchell TC, Ravetch JV, Wherry EJ: PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine. Nat Immunol 23(8): 1183-1192, August 2022 Notes: doi: 10.1038/s41590-022-01274-3.

Rishi R Goel, Mark M Painter, Kendall A Lundgreen, Sokratis A Apostolidis, Amy E Baxter, Josephine R Giles, Divij Mathew, Ajinkya Pattekar, Arnold Reynaldi, David S Khoury, Sigrid Gouma, Philip Hicks, Sarah Dysinger, Amanda Hicks, Harsh Sharma, Sarah Herring, Scott Korte, Wumesh Kc, Derek A Oldridge, Rachel I Erickson, Madison E Weirick, Christopher M McAllister, Moses Awofolaju, Nicole Tanenbaum, Jeanette Dougherty, Sherea Long, Kurt D'Andrea, Jacob T Hamilton, Maura McLaughlin, Justine C Williams, Sharon Adamski, Oliva Kuthuru, Elizabeth M Drapeau, Miles P Davenport, Scott E Hensley, Paul Bates, Allison R Greenplate, E John Wherry: Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine. Cell 185(11): 1875-1887, May 2022 Notes: doi: 10.1016/j.cell.2022.04.009.

Apostolidis SA, Sarkar A, Giannini HM, Goel RR, Mathew D, Suzuki A, Baxter AE, Greenplate AR, Alanio C, Abdel-Hakeem M, Sokratis A Apostolidis, Amrita Sarkar, Heather M Giannini, Rishi R Goel, Divij Mathew, Aae Suzuki, Amy E Baxter, Allison R Greenplate, Cécile Alanio, Mohamed Abdel-Hakeem, Oldridge DA, Giles JR, Wu JE, Chen Z, Huang YJ, Belman J, Pattekar A, Manne S, Kuthuru O, Dougherty J, Weiderhold B, Weisman AR, Ittner CAG, Gouma S, Dunbar D, Frank I, Huang AC, Vella LA; UPenn COVID Processing Unit, Reilly JP, Hensley SE, Rauova L, Zhao L, Meyer NJ, Poncz M, Abrams CS, Wherry EJ. : Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19. Front Immunol 13(834988), March 2022 Notes: doi: 10.3389/fimmu.2022.834988.

Goel RR, Painter MM, Apostolidis SA (co-first author), Mathew D, Meng W, Rosenfeld AM, Lundgreen KA, Reynaldi A, Khoury DS, Pattekar A, Gouma S, Kuri-Cervantes L, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Baxter AE, Oldridge DA, Giles JR, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Drapeau EM, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O; UPenn COVID Processing Unit‡, Frank I, Betts MR, Vella LA, Grifoni A, Weiskopf D, Sette A, Hensley SE, Davenport MP, Bates P, Luning Prak ET, Greenplate AR, Wherry EJ: mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern. Science 3(374): 6572, December 2021 Notes: doi: 10.1126/science.abm0829.

Apostolidis, SA, Kakara M, Painter MM, Goel RR, Mathew D, Lenzi K, Rezk A, Patterson KR, Espinoza DA, Kadri JC, Markowitz DM, E Markowitz C, Mexhitaj I, Jacobs D, Babb A, Betts MR, Prak ETL, Weiskopf D, Grifoni A, Lundgreen KA, Gouma S, Sette A, Bates P, Hensley SE, Greenplate AR, Wherry EJ, Li R, Bar-Or A.: Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy. Nat Med 27(11): 1990-2001, November 2021 Notes: doi: 10.1038/s41591-021-01507-2.