Samantha F Butts
Center for Reproductive Medicine and Surgery
University of Pennsylvania Medical Center
3701 Market Street, 8th Floor
Philadelphia, PA 19104
BA (History and Science-cum laude)
Harvard University, Cambridge MA, 1994.
Harvard University School of Medicine, Boston, MA, 1998.
University of Pennsylvania School of Medicine, Philadelphia, PA, 2006.
Description of Research ExpertiseEnvironmental Reproductive Toxicology; Reproductive Health Disparities; Reproductive Senescence; In Utero Programming of Ovarian Function and Somatic Growth
Description of Clinical ExpertiseReproductive Surgery, In Vitro Fertilization, Early Menopause, Diminished Ovarian Reserve, Ovulation Induction
Selected PublicationsHansen K, He ALW, Styer AK, Wild RA, Butts S, Engmann L, Diamond MP, Legro RS, Coutifaris C, Alvero R, Robinson RD, Casson P, Christman GM, Huang H, Santoro N, Eisenberg E, Zhang H.: Predictors of Pregnancy and Live-Birth in Couples with Unexplained Infertility following Ovarian Stimulation-Intrauterine Insemination Fertility and Sterility 105(6): 1575-1583. 2016.
McLaren JF, Barnhart KT, Sammel MD, Appleby DH, Butts SF: Success of the two-dose methotrexate protocol for treatment of ectopic pregnancy in women with a history of prior ectopic pregnancy. J Reprod Med 59(4): 379-384, August 2014.
Butts S, Sammel MD, Greer C, Rebbeck TR, Boorman DW, Freeman EW: Cigarettes, genetic background and early menopause: The presence of single nucleotide polymorphisms in Cytochrome P450 genes hastens the onset of natural menopause in European American Smokers. Menopause 21(7): 694-701, July 2014.
Roe A, Hillman J, Butts S, Smith M, Playford M, Rader D, Mehta NN, Dokras A: Decreased cholesterol efflux capacity and atherogenic lipid profile in young women with PCOS. J Clin Endocrinol Metab 99(5): E841-E847 May 2014.
Sathyanarayana S, Barrett E, Butts S, Wang C, Swan S: Phthalate Exposure and Reproductive Hormone Concentrations in Pregnancy. Reproduction 147: 401-409, April 2014.
Wishall KM, Price J, Pereira N, Butts S, Della Badia C.: Postablation Risk Factors for Pain and Subsequent Hysterectomy. Obstet Gynecol 124(5): 904-910, 2014 Notes: Editors pick for November 2014 issue of Obstetrics and Gynecology
Butts SF, Owen C, Mainigi M, Senapati S, Seifer DB, Dokras A.: Assisted hatching and intracytoplasmic sperm injection are not associated with improved outcomes in assisted reproduction cycles for diminished ovarian reserve: An analysis of cycles in the United States from 2004 to 2011. Fertil Steril 102(4): 1041-1047, 2014.
Butts SF, Shaunik A, Guo Wensheng, Cary MS, Chung K, Takacs P, Sammel MD, Barnhart KT: Predicting the decline in serum human chorionic gonadotropin in miscarriage: Redefining the normal curve in a diverse population Obstet Gynecol 122(2): 337-343, August 2013.
Butts SF, Ratcliffe S, Dokras A, Seifer DB: Diagnosis and treatment of diminished ovarian reserve in ART cycles of women up to age 40: The role of insurance mandates. Fertil Steril 99:382-88, February 2013.
Butts SF, Freeman EW, Sammel MD, Queen K, Lin H, Rebbeck T: The joint effect of smoking and gene variants involved in sex steroid metabolism on hot flashes in late reproductive age women. J Clin Endocrinol Metabol 97 (6): E1032–E1042, June 2012.