Nalaka S. Gooneratne

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Nalaka S. Gooneratne, M.D., M.Sc.

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia and the Veteran's Administration Medical Center
Department: Medicine
Graduate Group Affiliations

Contact information
Ralston Penn Center, Room 220
3615 Chestnut Street
Philadelphia, PA 19104
Office: (215) 349-5938
Fax: (215) 573-8684
Education:
Cert. (French)
Ecole de Français Moderne, Université de Lausanne, Switzerland, 1989.
B.S. (Medical Education)
Northwestern University (Honors Program) (Graduated with Distinction), 1991.
M.D. (Medicine)
Northwestern University School of Medicine (Graduated with Distinction), 1993.
M.Sc. (Clinical Epidemiology)
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 2002.
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Description of Research Expertise

Research Interests:

Aging, sleep, complementary/alternative medicine, melatonin, cancer epidemiology, patient-oriented research, translational research, categorical data, clinical trials, multivariate analysis, time series.

Description of Research:

Dr. Gooneratne’s research interests are centered around studying the nature of sleep disorders in the elderly. While many older adults complain of difficulties with sleep, it is an area about which modern medicine has only a limited understanding. Funded initially by a National Institute on Aging Mentored Research Career Development Award (K23) and a National Center for Complementary and Alternative Medicine Research Award (R01), he is pursuing research examining the role of melatonin, a hormone secreted by the pineal gland, in sleep in the elderly. Dr. Gooneratne also has a strong interest in the attitudes of senior citizens towards their sleep problems and how their background/ethnicity informs their decisions. This project has been funded by a Hartford foundation/Penn Center for Excellence pilot grant. Dr.Gooneratne also runs a Sleep Disorders Clinic for Seniors in an effort to address the medical needs of older patients with sleep disorders. In addition, Dr. Gooneratne is the Associate Program Director of the Clinical and Translational Research Center of the University of Pennsylvania's Clinical and Translational Science Award, which assists in the conduct of over 190 clinical research studies. He also helps to coordinate the research activities of the Geriatric fellows in the Division of Geriatric Medicine and mentors research fellows in the Division of Sleep Medicine.

Description of Clinical Expertise

Dr. Gooneratne's clinical focus is in the area of sleep disorders in older adults. He has been invited to lecture on this topic at national conferences, such as those hosted by the American Association of Sleep Medicine, the American Thoracic Society as well as the National Institutes of Health State-of-the-Science conference on Chronic Insomnia. Dr. Gooneratne runs a Sleep Disorders Clinic for Seniors which is tailored to the unique needs of older adults as they seek to address their sleep disturbances.

Selected Publications

Gooneratne, N.S.: Respiratory Diseases: Questions and Critique. Geriatrics Review Syllabus, 8th ed. Sullivan, G.M., Gazewood, J.D., Kennedy, G.J., Soriano, R.P. (eds.). American Geriatrics Society, New City, NY, in press 2012.

Grandner, M. A., Jackson, N. J., Pigeon, W. R., Gooneratne, N. S. and Patel, N. P.: State and Regional Prevalence of Sleep Disturbance and Daytime Fatigue. J Clin Sleep Med in press 2012.

Grandner, M. A., Martin, J. L., Patel, N. P., Jackson, N. J., Gehrman, P. R., Pien, G. W., Perlis, M. L., Xie, D., Sha, D., Weaver, T., and Gooneratne, N. S. : Age and sleep disturbances among american men and women: Data from the U.S. Behavioral Risk Factor Surveillance System. Sleep in press 2012.

Gooneratne, N.S., Edwards, Y.Z., Zhou, C., Cuellar, N., Grandner, M.A, Barrett, J.S. : Melatonin pharmacokinetics following two different oral surge-sustained release doses in older adults. J Pineal Res in press 2012.

Grandner, M.A., Patel, N.P., Gehrman, P.R., Xie, D., Sha, D., Michael L. Perlis, M.L., Weaver, T., Teff, K., Gooneratne, N.S. : Obesity, diabetes and exercise predict sleep-related complaints in the American population. Journal of Public Health electronic publication: 1-12, Sep 2011 Notes: http://www.springerlink.com/content/840xv644533r5213/

Hanisch, L.J., Gooneratne, N.S., Soin, K., Gehrman, P.R., Vaughn, D.J., Coyne, J.C.: Sleep and daily functioning during androgen deprivation therapy for prostate cancer. European Journal Cancer Care (Engl) 20(4): 549-54, Jul 2011 Notes: Epub: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2354.2010.01226.x/pdf.

Rose, K.M., Beck, C., Tsai, P-F., Liem, P.H., Davila, D.D., Kleban, M., Gooneratne, N.S., Kalra, G., Richards, K.C.: Sleep disturbances and nocturnal agitation behaviors in older adults with dementia. Sleep 34(6): 779-786, Jun 2011.

Gooneratne, N.S., Patel, N.P., Perlis, M.L., Gehrman, P.R., Xie, D., Sha, D., Pigeon, W.R., Teff, K., Weaver, T., Grandner, M.A.: Overweight, obesity, diabetes and exercise associated with sleep disturbance and daytime fatigue in the American population. Associated Professional Sleep Societies Annual Conference, Minneapolis, MN Jun 2011 Notes: (poster presentation).

Spindler, M., Gooneratne, N.S., Siderowf, A., Duda, J.E., Cantor, C.R., Dahodwala, N.: Daytime sleepiness is a risk factor for falls in Parkinson's disease. International Congress of Parkinson's Disease and Movement Disorders (Movement Disorder Society), Toronto, Canada Jun 2011 Notes: (poster presentation).

Grandner, M.A., Hale, L., Nicholas, J., Jackson, N.J., Patel, N.P., Gooneratne, N.S., Troxel, W.M.: Sleep disturbance and daytime fatigue associated with perceived racial discrimination. Associated Professional Sleep Societies Annual Conference, Minneapolis, MN Jun 2011 Notes: (poster presentation).

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Last updated: 12/29/2011
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