faculty photo

Kurt David Hankenson

Assistant Professor of Orthopaedic Surgery
Department: Orthopaedic Surgery

Contact information
University of Pennsylvania
School of Veterinary Medicine
Dept of Clinical Studies
New Bolton Center
382 West Street Road
Kennett Square, PA 19348
Office: 610-925-6115
Fax: 610-925-6821
Education:
(Liberal Arts and Sciences)
University of Illinois, 1988.
B.S. (Veterinary Science)
University of Illinois, 1990.
D.V.M. (Veterinary Medicine)
University of Illinois, 1992.
M.S. (Veterinary Anatomy)
Purdue University, 1997.
Ph.D. (Biochemistry)
University of Washington, 2001.
Post-Graduate Training
Senior Research Fellow, University of Washington, School of Medicine, Department of Biochemistry, Seattle, WA. , 1997-2002.
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Description of Research Expertise

bone biology
mesenchymal stem cell
orthopaedic tissue engineering
Bone regeneration and repair
Osteoporosis
Extracellular Matrix
Stem Cells
Bone regeneration/repair
Mesenchymal Stem Cell
Osteoporosis
Orthopaedic tissue engineering

Selected Publications

Singh Lakshman, Brennan Tracy A, Kim Jung-Hoon, Egan Kevin P, McMillan Emily A, Chen Qijun, Hankenson Kurt D, Zhang Yi, Emerson Stephen G, Johnson F Brad, Pignolo Robert J: Long-term functional engraftment of mesenchymal progenitor cells in a mouse model of accelerated aging. Stem cells (Dayton, Ohio) 31(3): 607-11, Mar 2013.

Zhu Fengchang, Sweetwyne Mariya T, Hankenson Kurt D: Pkcδ Is Required for Jagged-1 Induction of hMSC Osteogenic Differentiation. Stem cells (Dayton, Ohio) Feb 2013.

Zhu Fengchang, Friedman Michael S, Luo Weijun, Woolf Peter, Hankenson Kurt D: The transcription factor osterix (SP7) regulates BMP6-induced human osteoblast differentiation. Journal of cellular physiology 227(6): 2677-85, Jun 2012.

Miedel Emily, Dishowitz Michael I, Myers Marc H, Dopkin Derek, Yu Yan-Yiu, Miclau Ted S, Marcucio Ralph, Ahn Jaimo, Hankenson Kurt D: Disruption of thrombospondin-2 accelerates ischemic fracture healing. Journal of orthopaedic research : official publication of the Orthopaedic Research Society Dec 2012.

Volk Susan W, Wang Yanjian, Hankenson Kurt D: Effects of donor characteristics and ex vivo expansion on canine mesenchymal stem cell properties: implications for MSC-based therapies. Cell transplantation 21(10): 2189-200, 2012.

Dishowitz Michael I, Terkhorn Shawn P, Bostic Sandra A, Hankenson Kurt D: Notch signaling components are upregulated during both endochondral and intramembranous bone regeneration. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 30(2): 296-303, Feb 2012.

Hankenson Kurt D, Dishowitz Michael, Gray Chancellor, Schenker Mara: Angiogenesis in bone regeneration. Injury 42(6): 556-61, Jun 2011.

Laurita Jason, Koyama Eiki, Chin Bianca, Taylor Jesse A, Lakin Gregory E, Hankenson Kurt D, Bartlett Scott P, Nah Hyun-Duck: The Muenke syndrome mutation (FgfR3P244R) causes cranial base shortening associated with growth plate dysfunction and premature perichondrial ossification in murine basicranial synchondroses. Developmental dynamics : an official publication of the American Association of Anatomists 240(11): 2584-96, Nov 2011.

Scheller Erica L, Leinninger Gina M, Hankenson Kurt D, Myers Martin G, Krebsbach Paul H: Ectopic expression of Col2.3 and Col3.6 promoters in the brain and association with leptin signaling. Cells, tissues, organs 194(2-4): 268-73, 2011.

Lin Grace L, Hankenson Kurt D: Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation. Journal of cellular biochemistry 112(12): 3491-501, Dec 2011.

Scheller Erica L, Hankenson Kurt D, Reuben Jayne S, Krebsbach Paul H: Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. Journal of cellular biochemistry 112(11): 3364-72, Nov 2011.

Luo Weijun, Friedman Michael S, Hankenson Kurt D, Woolf Peter J: Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization. BMC systems biology 5: 82, 2011.

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Last updated: 11/05/2013
The Trustees of the University of Pennsylvania