Untitled Document

Charles A. Stanley

Emeritus Professor CE of Pediatrics

Department: Pediatrics

Contact information

Children's Hospital of Philadelphia
34th Street & Civic Center Blvd
Philadelphia, PA 19104

Office: 2155903420
Fax: 2155901605

Education:
B.A. (Biochemical Sciences)
Harvard University, 1964.
M.D. (Medicine)
University of Virginia School of Medicine, 1970.

Links
Hyperinsulinism Center at CHOP

Post-Graduate Training
Resident in Pediatrics, Children's Hospital of Philadelphia, 1970-1972.
Fellowship in Metabolic Diseases, Children's Hospital of Philadelphia, 1972-1975.

Permanent link

Description of Research Expertise

genetic disorders of carbohydrate and fatty acid metabolism, insulin secretion

Description of Clinical Expertise

hypoglycemia, glycogenoses, fatty acid oxidation disorders, diabetes mellitus

Selected Publications

States LJ, Becker S, Zhuang H, Adzick NS, Stanley CA: Detection of a Focal Lesion of Congenital Hyperinsulinism using 18[F]-DOPA PET/CT: Lessons learned from 100 consecutive studies with histologic confirmation performed at the Children’s Hospital of Philadelphia. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Pinney SE, Ganapathy K, Bradfield J, Givler S, Becker S, Hughes N, Stokes D, Stanley CA: Novel form of Autosomal Dominant Hyperinsulinism Maps to Chromosome 10q21. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Lord K, Snider K, MacMullen C, Becker S, Ganguly A, Stanley CA: "Missing" Mutations: Post-zygotic Mosaicism in Congenital Hyperinsulinism. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Li C, Patel P, Zhang T, Chen P, Givler S, Liu C, Nissim I, Naji A, Matschinsky FM, De Leon DD, Stanley CA: [U-13C]-glucose metabolism in islets from infants with KATP hyperinsulinism. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Stanescu DE, Hughes N, Kaplan B, Stanley CA, De Leon DD: Novel Presentations of Congenital Hyperinsulinism due to Mutations in the MODY genes: HNF1A and HNF4A. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Hughes N, Snider K, Carrie Coleman-Campbell C, Sayed S, Shen G, Boyajian L, Ganguly A, Stokes D, Stanley CA: Mitochondrial Uncoupling Protein 2 (UCP2) Mutations in CHOP Hyperinsulinism (HI) Patients. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Patel P, Li C, Givler S, Matschinsky F, Stanley CA, De Leon DD: Functional Evaluation of Islets from Infants with KATP Hyperinsulinism. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Conlin LK, Thiel BD, Mulchandani S, Kalish JM, Snider KE, Bhatti TR, Ernst LM, Biegel JA, Spinner NB, Stanley CA, Deardorff MA: Detection and quantification of mosaic isodisomy in Beckwith-Wiedemann patients using SNP arrays. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Kalish JM, Snider K, Conlin KL, Bhatti T, Ganguly A, Stanley CA, Deardorff MA: The Spectrum of Hyperinsulinism in Mosaic Beckwith-Wiedemann Syndrome: Dissection of 11p15 Paternal Uniparental Isodisomy. “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.

Snider KE, Ganguly A, Becker S, Boyajian L, Shyng SL, MacMullen C, Hughes N, Ganapathy K, Bhatti T, Lee A, Stanley CA: Genotype-phenotype correlation in 440 children with congenital hyperinsulinism (HI). “Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes” Symposium, The Children’s Hospital of Philadelphia March 2012.