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Frederick F. Samaha

Associate Professor of Medicine at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center
Department: Medicine

Contact information
Cardiology Section 111C
Philadelphia VA Medical Center
University and Woodland Avenues
Philadelphia, PA 19104
Office: (215) 823-6324
Education
B.A. (Chemistry)
Kenyon College, 1983.
M.D. (Medicine)
University of Cincinnati College of Medicine, 1987.
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Description of CVI Expertise

Chief, Cardiovascular Section,
Philadelphia Veterans Administration Medical Center


CVI Program Unit Administrator (Co-Director):
Lipid / Atherosclerosis / CAD / ACS / Prevention

Selected Publications

Wusheng Yan, Laurence Suaud, Frederick F. Samaha, Thomas R. Kleyman and Ronald C. Rubenstein: Regulation of the T663A Functional Polymorphism of Human [alpha] ENaC by Phosphorylation. Cystic Fibrosis Meetings 2005.

Samaha FF*, Rubenstein R*, Yan W, Levy D, Ahn Y, Townsend R, Ferrel R and Kleyman TR (*These authors contributed equally to this study).: Functional Polymorphism in the Carboxyl Terminus of the Alpha Subunit of the Epithelial Sodium Channel. J Biol Chem 279: 23900-23907, 2004.

Wusheng Yan, Frederick F. Samaha, Mohan Ramkumar, Thomas R. Kleyman and Ronald Rubenstein: CFTR Differentially Regulates Human and Murine Epithelial Sodium Channels in Xenopus oocytes Due to Differences in the C-terminus of the ENaC cx Subunit. J Biol Chem 279: 23183-23192, 2004.

Stern L, Iqbal N, Seshadri P, Chicano KL, Daily DA, McGrory J, Williams M, Gracely EJ, Samaha FF: Outcomes at one year after randomization to a low carbohydrate as compared to low fat diet in severe obesity. Ann Int Med 140: 778-785, 2004.

Seshadri P, Nayyar I, Stern L, Williams M, Samaha FF: Effects of a Low Carbohydrate Diet as Compared with a Conventional Diet on Lipoprotein Subfractions and C-Reactive Protein. Am J Med In press, 2004.



Hiatt WR, Hirsch A, Cooke J, Olin JW, Brate DC, and Creager MA: Treatment of Claudication with AT 1015, A Novel 5-Hydroxytryptamine Antagonist: The U.S. Experience. Vascular Medicine 9(1): 18-25, February 2004.



Samaha FF: Commentary: Trial finds low carb diets reduce weight more than low fat diets in the short term, but have more adverse effects. Journal of Evidence-Based Cardiovascular Medicine In press, 2004.

Rubenstein, RC, Yan W, Suaud L, Samaha FF, and Kleyman TR.: The T663a Functional Polymorphism of Human [alpha]-ENaC: Differential Regulation by Protein Kinase C. Am J Resp. Crit Care Med (Oral) 169(A669 ), 2004.

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Last updated: 03/04/2008
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