Mark L. Kahn, M.D., B.A.
Professor of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
BRB II/III Room 952
421 Curie Boulevard
University of Pennsylvania
Philadelphia, PA 19104
421 Curie Boulevard
University of Pennsylvania
Philadelphia, PA 19104
Office: (215) 898-9007
Fax: (215) 573-2094
Fax: (215) 573-2094
Email:
markkahn@mail.med.upenn.edu
markkahn@mail.med.upenn.edu
Publications
Links
Search PubMed for articles
Kahn Lab (CVI)
Cardiovascular Institute
Cardiovascular Division Faculty
Cell and Molecular Biology Graduate Group
Pharmacological Sciences Graduate Group
Search PubMed for articles
Kahn Lab (CVI)
Cardiovascular Institute
Cardiovascular Division Faculty
Cell and Molecular Biology Graduate Group
Pharmacological Sciences Graduate Group
Education:
B.A. (Science)
Brown University, 1984.
M.D. (Internal Medicine)
Brown University School of Medicine, 1987.
Permanent linkB.A. (Science)
Brown University, 1984.
M.D. (Internal Medicine)
Brown University School of Medicine, 1987.
Description of CVI Expertise
CVI Program Unit(s):Cardiovascular Development / Congenital Heart Disease
Thrombosis / Hemostasis
CVI Research Description:
The Kahn Lab investigates signaling pathways in platelets that mediate thrombosis and signaling pathways in vascular endothelial cells of the blood and lymphatic system utilized during cardiovascular development.
Selected Publications
Yuan LJ, Wang T, Kahn ML, Ferrari VA: High-resolution echocardiographic assessment of infarct size and cardiac function in mice with myocardial infarction. Journal of the American Society of Echocardiography Page: 219-26, Feb 2011.Rubio-Garcia J, Coppel Y, Lecante P, Mingotaud C, Chaudret B, Gauffre F, Kahn ML. : One-step synthesis of metallic and metal oxide nanoparticles using amino-PEG oligomers as multi-purpose ligands: size and shape control, and quasi-universal solvent dispersibility. Chemistry Communications (Cambridge England) Page: 988-90, Jan 2011.
Winkelmann R, Sandrock L, Porstner M, Roth E, Mathews M, Hobeika E, Reth M, Kahn ML, Schuh W, Jäck HM.: B cell homeostasis and plasma cell homing controlled by Kruppel-like factor 2. Proceedings of the National Academy of Sciences of the United States of America 108(2): 710-5, Jan 2011 Notes: [Epub 2010, Dec. 27.
Bertozzi CC, Hess PR, Kahn ML.: Platelets: covert regulators of lymphatic development. Arteriosclerosis Thrombosis and Vascular Biology 12: 2368-71, Dec 2010.
Zheng Xiangjian, Xu Chong, Di Lorenzo Annarita, Kleaveland Benjamin, Zou Zhiying, Seiler Christoph, Chen Mei, Cheng Lan, Xiao Jiping, He Jie, Pack Michael A, Sessa William C, Kahn Mark L: CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations. The Journal of Clinical Investigation 120(8): 2795-804, Aug 2010.
Bertozzi Cara C, Schmaier Alec A, Mericko Patricia, Hess Paul R, Zou Zhiying, Chen Mei, Chen Chiu-Yu, Xu Bin, Lu Min-min, Zhou Diane, Sebzda Eric, Santore Matthew T, Merianos Demetri J, Stadtfeld Matthias, Flake Alan W, Graf Thomas, Skoda Radek, Maltzman Jonathan S, Koretzky Gary A, Kahn Mark L: Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood 116(4): 661-70, Jul 2010.
Kahn Mark L: Jazzing up vessel growth. Blood 115(8): 1479, Feb 2010.
Schmaier Alec A, Zou Zhiying, Kazlauskas Arunas, Emert-Sedlak Lori, Fong Karen P, Neeves Keith B, Maloney Sean F, Diamond Scott L, Kunapuli Satya P, Ware Jerry, Brass Lawrence F, Smithgall Thomas E, Saksela Kalle, Kahn Mark L: Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proceedings of the National Academy of Sciences of the United States of America 106(50): 21167-72, Dec 2009.
Schmaier Alec A, Kahn Mark L: Platelet integrin signaling: wherefore art thou? Blood 114(13): 2571-2, Sep 2009.
Zhiying Zou, Alec A. Schmaier, Lan Cheng, Patricia Mericko, S. Kent Dickeson, Thomas P. Stricker, Samuel A. Santoro and Mark L. Kahn: Negative regulation of activated α2 integrins during thrombopoiesis. Blood Jun 2009.