Louis J. Soslowsky

faculty photo
Fairhill Professor of Orthopaedic Surgery
Director of McKay Orthopaedic Research Laboratory, University of Pennsylvania
Director of Orthopaedic Research, University of Pennsylvania
Member, Institute for Medicine and Engineering, University of Pennsylvania
Director of Basic Science Research, Shoulder and Elbow Service, University of Pennsylvania
Vice Chair for Research, Department of Orthopaedic Surgery, University of Pennsylvania (reappointed 2009)
Professor, Department of Bioengineering, University of Pennsylvania
Fellow, Institute of Aging, University of Pennsylvania
Founding Director, Penn Center for Musculoskeletal Disorders, University of Pennsylvania (Type 1 center designation in 2008)
Member, Institute for Translational Medicine and Therapeutics
Executive Committee, University of Pennsylvania, Department of Bioengineering
Search Committee, University of Pennsylvania, Institute for Regenerative Medicine
Department: Orthopaedic Surgery

Contact information
McKay Orthopaedic Research Laboratory
424 Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-898-8653
Fax: 215-573-2133
Education:
Diploma
East Brunswick High School , 1982.
B.S. (Engineering Mechanics)
Columbia University, 1986.
M.S. (Engineering Mechanics)
Columbia University, 1987.
M.Phil
Columbia University, 1989.
Ph.D. (Engineering Mech./Biomechanics, Mentor: Van C. Mow)
Columbia University, 1991.
Cert. (Academic Medicine Leadership Program)
Wharton School of the University of Pennsylvania , 2008.
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Description of Research Expertise

orthopaedic research, orthopaedic biomechanics and tissue engineering, tendons and ligaments, shoulder and elbow

Description of Itmat Expertise

Dr. Soslowsky's research program involves orthopaedic biomechanics and functional tissue engineering with an emphasis on tendon and ligament injury, repair, and regeneration.

Selected Publications

Dunkman, A., Buckley, M.R., Mienaltowski, M.J., Adams, S.M., Thomas, S.J., Satchell, L., Kumar, A., Pathmanathan, L., Beason, D.P., Iozzo, R.V., Birk, D.E., Soslowsky, L.J.: The Tendon Injury Response Is Influenced by Decorin and Biglycan. Ann Biomed Eng 42(3): 619-30, 2014.

Riggin CN, Sarver JJ, Freedman BR, Thomas SJ, Soslowsky LJ.: Analysis of Collagen Organization in Mouse Achilles Tendon Using High-Frequency Ultrasound Imaging. J Biomech Eng 136(2): 02102, 2014.

Thomas SJ, Reuther KE, Tucker JJ, Sarver JJ, Yannascoli SM, Caro AC, Voleti PB, Rooney SI, Glaser DL, Soslowsky LJ: Biceps Detachment Decreases Joint Damage in a Rotator Cuff Tear Rat Model. Clin Orthop Relat Res 472(8): 2404-12, 2014.

Freedman BR, Gordon JA, Soslowsky LJ. : The Achilles Tendon: Fundamental Properties and Mechanisms Governing Healing Muscles, Ligaments and Tendons Journal 4(2): 245-55, 2014.

Connizzo BK, Bhatt PR, Liechty KW, Soslowsky, LJ: Diabetes Alters Mechanical Properties and Collagen Fiber Re-Alignment in Multiple Mouse Tendons. Ann Biomed Eng 42(9): 1880-8, 2014.

Dunkman AA, Buckley MR, Mienaltowski MJ, Adams SM, Thomas SJ, Kumar A, Beason DP, Iozzo RV, Birk DE, Soslowsky LJ: The Injury Response of Aged Tendons in the Absence of Biglycan and Decorin. Matrix Biol(35), 232-8, 2014.

Caro, A: Efficacy of Various Analgesics on Shoulder Function and Rotator Cuff Tendon to Bone Healing in a Rat (Rattus norvegicus) Model. JAALAS 53(2): 185-92, 2014.

Connizzo BK, Yannascoli SM, Tucker JJ, Caro AC, Riggin CN, Mauck RL, Soslowsky LJ, Steinberg DR, Bernstein J: The Detrimental Effects of Systemic Ibuprofen Delivery on Tendon Healing Are Time-Dependent Clin Orthop Relat Res. 472(8): 2433-9, 2014.

Reuther KE, Thomas SJ, Tucker JJ, Sarver JJ, Gray CF, Rooney SI, Glaser DL, Soslowsky LJ.: Disruption of the anterior-posterior rotator cuff force balance alters joint function and leads to joint damage in a rat model. J Orthop Res 32(5): 638-44, 2014.

Beason, D.P.; Tucker, J.J.; Edelstein, L.; Lee, C.S.; Abboud, J.A.; Soslowsky, L.J.: Rat Rotator Cuff Tendon-to-Bone Healing Properties are Adversely Affected by Hypercholesterolemia. J Shoulder Elbow Surg 23(6): 867-72, 2014.

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Last updated: 09/17/2014
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