Adda Grimberg
Professor of Pediatrics (Endocrinology and Diabetes) at the Children's Hospital of Philadelphia
Attending Physician, Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia
Member, Abramson Cancer Center , Perelman School of Medicine, University of Pennsylvania, Philadelphia PA
Member, Children's Hospital of Philadelphia (Joseph Stokes Jr.) Research Institute, The Children's Hospital of Philadelphia, Philadelphia, PA
Member, Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Member, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Scientific Director, Diagnostic and Research Growth Center , The Children's Hospital of Philadelphia
Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA
Member, Anna T. Meadows Society , Perelman School of Medicine Clinician Educators, University of Pennsylvania
Member, Penn Association of Senior and Emeritus Faculty, University of
Pennsylvania, Philadelphia, PA
Department: Pediatrics
Contact information
The Children's Hospital of Philadelphia
The Hub for Clinical Collaboration
Division of Endocrinology, 7th floor.
3500 Civic Center Boulevard
Philadelphia, PA 19104
The Hub for Clinical Collaboration
Division of Endocrinology, 7th floor.
3500 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-3618
Fax: 215-590-3053
Fax: 215-590-3053
Email:
grimberg@chop.edu
grimberg@chop.edu
Links
my CHOP Research Institute webpage
April/May 2017 issue of CHOP Bench to Bedside highlighting the new Pediatric Endocrine Society guidelines for growth hormone and insulin-like growth factor-I treatment that I chaired/authored
my CHOP Research Institute webpage
April/May 2017 issue of CHOP Bench to Bedside highlighting the new Pediatric Endocrine Society guidelines for growth hormone and insulin-like growth factor-I treatment that I chaired/authored
Education:
B.S. (Biology [Genetics and Development])
Cornell University College of Agriculture and Life Sciences, 1989.
M.D. (Medicine)
Cornell University Medical College, 1993.
B.S. (Biology [Genetics and Development])
Cornell University College of Agriculture and Life Sciences, 1989.
M.D. (Medicine)
Cornell University Medical College, 1993.
Post-Graduate Training
Residency in General Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 1993-1996.
Fellowship in Pediatric Endocrinology, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 1996-1999.
Patient Oriented Research Certificate, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2001-2002.
Introduction to Health Policy and Health Services Research (HPR600), Perelman School of Medicine, University of Pennsylvania, 2014-2014.
Physician Leadership Program, Children’s Hospital of Philadelphia , 2019-2020.
Permanent linkResidency in General Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 1993-1996.
Fellowship in Pediatric Endocrinology, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 1996-1999.
Patient Oriented Research Certificate, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2001-2002.
Introduction to Health Policy and Health Services Research (HPR600), Perelman School of Medicine, University of Pennsylvania, 2014-2014.
Physician Leadership Program, Children’s Hospital of Philadelphia , 2019-2020.
Description of Itmat Expertise
Dr. Grimberg is a translational physician scientist focusing on growth regulation at both the systemic and cellular levels. Through a combination of in vitro research and clinical investigations, her goal is to advance understanding of growth biology and apply the molecular biology of the growth hormone/insulin-like growth factor(IGF)axis to improving care of children with growth problems.Selected Publications
Sue Groveman, Joerg Klepper, Klaus-Peter Liesenkötter, Cagla Fenton, Sarah Brooks, Adda Grimberg, and A. G. Christina Bergqvist : “Diagnosis and Treatment of Growth Hormone Deficiency in Children on the Ketogenic Diet: A Case Series,” Epilepsia 2024.Patricia R. Roby, Adda Grimberg, Christina L. Master, and Kristy B. Arbogast: Menstrual cycle patterns following concussion in adolescent patients. Journal of Pediatrics February 2023 Notes: Online ahead of print.
Ettya R. Fremont, Elizabeth A. Friedrich, Adda Grimberg, and Victoria A. Miller: Youth and parent perceptions of youth decision-making roles regarding evaluation for short stature. Children’s Health Care January 2023.
Camilia Kamoun, Victoria A. Miller, Chris Feudtner, Elizabeth A. Friedrich, and Adda Grimberg: Views on Short Stature of Female Versus Male Endocrine Pediatric Patients Undergoing Provocative Growth Hormone Testing and Their Parents. Endocrine Practice 2023 Notes: Online ahead of print.
Mohamad Maghnie, Michael B Ranke, Mitchell E Geffner, Elpis Vlachopapadopoulou, Lourdes Ibáñez, Martin Carlsson, Wayne Cutfield, Raoul Rooman, Roy Gomez, Michael P Wajnrajch, Agnès Linglart, Renata Stawerska, Peter E Clayton, Feyza Darendeliler, Anita C S Hokken- Koelega, Reiko Horikawa, Toshiaki Tanaka, Helmuth-Günther Dörr, Kerstin Albertsson- Wikland, Michel Polak, and Adda Grimberg: Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort. Journal of Clinical Endocrinology and Metabolism 107(12): 3287–3301, December 2022 Notes: -Selected for accompanying commentary: Abucham J and Boguszewski MCS. From the full KIGS cohort: On safety and efficacy of growth hormone treatment. J Clin Endocrinol Metab. 2023; 108: e1-e2. - Top 10 papers of JCEM published that year.
Ettya R. Fremont, Elizabeth A. Friedrich, Chris Feudtner, Adda Grimberg, and Victoria A. Miller: Perceptions of Youth and Parent Decision-Making Roles Regarding Recombinant Human Growth Hormone Treatment Endocrines 3(4): 590-600, October 2022 Notes: https://doi.org/10.3390/endocrines3040050.
Gerarda Cappuccio, Nicola Brunetti-Pierri, Paul Clift, Christopher Learn, John C. Dykes, Catherine L. Mercer, Bert Callewaert, Ilse Meerschaut, Alessandro Mauro Spinelli, Irene Bruno, Matthew J Gillespie, Aaron T Dorfman, Adda Grimberg, Mark E. Lindsay, and Angela E. Lin: Expanded Cardiovascular Phenotype of Myhre Syndrome Includes Tetralogy of Fallot Suggesting a Role for SMAD4 in Human Neural Crest Defects. American Journal of Medical Genetics Part A 188(5): 1384-1395, 2022.
Colin P. Hawkes, Hareesh Gunturi, Andrew N. Dauber, Joel N. Hirschhorn, and Adda Grimberg: Racial/Ethnic Disparities in the Investigation and Treatment of Pediatric Growth Hormone Deficiency. Journal of Pediatrics 236: 238-245, 2021 Notes: highlighted in Eric Seaborg, “Sex, Race, and Measuring Tape: Health Disparities and Growth Hormone Deficiency,” Endocrine News, February 2022, pp. 30-32.
Camilia Kamoun, Colin P. Hawkes, Hareesh Gunturi, Andrew N. Dauber, Joel N. Hirschhorn, and Adda Grimberg: Growth Hormone Stimulation Testing Patterns Contribute to Sex Differences in Pediatric Growth Hormone Treatment. Hormone Research in Paediatrics 94(9-10): 353-363, 2021 Notes: (highlighted in Eric Seaborg, “Sex, Race, and Measuring Tape: Health Disparities and Growth Hormone Deficiency,” Endocrine News, February 2022, pp. 30-32.).
Joseph M. Kindler, Ellen L. Mitchell, David A. Piccoli, Adda Grimberg, Mary B. Leonard, Kathleen M. Loomes, and Babette S. Zemel: Bone Geometry and Microarchitecture Deficits in Children with Alagille Syndrome. Bone 141: 115576, December 2020.